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ARS Home » Northeast Area » Boston, Massachusetts » Jean Mayer Human Nutrition Research Center On Aging » Research » Publications at this Location » Publication #230670
Title: Vitamin E and Cancer

Author
item NEGIS, YESIM - JM USDA HNRCA @ TUFTS
item ZINGG, JEAN-MARC - JM USDA HNRCA @ TUFTS
item LIBINAKI, ROKSAN - MONASH UNIVERSITY
item Meydani, Mohsen
item AZZI, ANGELO - JM USDA HNRCA @ TUFTS

Submitted to: Nutrition and Cancer
Publication Type: Proceedings
Publication Acceptance Date: 7/1/2009
Publication Date: 11/10/2009
Citation: Negis Y, Zingg J-M, Libinaki R, *Meydani M*, Azzi A. Vitamin E and Cancer. Nutr & Cancer. 2009; 61: 875-878.

Interpretive Summary:

Technical Abstract: Protection by vitamin E against free radical-induced DNA mutations appears not to be an effective occurrence. On the other hand, in vitro evidence that different tocopherols slow down cell proliferation is an accepted observation. However, such an event may not be sufficient to result in beneficial clinical outcomes. Tocopheryl-phosphate, a more active, natural derivative of tocopherol, endowed with prevention and therapeutic potential, represents a possible key to the understanding of the present conflict between laboratory and clinical results.