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United States Department of Agriculture

Agricultural Research Service

Research Project: UMBRELLA PROJECT FOR FOOD SAFETY

Location: Warmwater Aquaculture Research Unit

Title: The contribution of transcriptomic and proteomic analysis in elucidating stress adaptation responses of Listeria monocytogenes

Authors
item Soni, Kamleshhumar -
item Nannapaneni, Ramakrishna -
item Tasara, Taurai -

Submitted to: Foodborne Pathogens and Disease
Publication Type: Review Article
Publication Acceptance Date: February 22, 2011
Publication Date: August 8, 2011
Citation: Soni, K., Nannapaneni, R., Tasara, T. 2011. The contribution of transcriptomic and proteomic analysis in elucidating stress adaptation responses of Listeria monocytogenes. Foodborne Pathogens and Disease. 8:842-852.

Interpretive Summary: Understanding of stress adaptation will allow scientists and industry to develop systems to minimize L monocytogenes survival in foods and in food processing environments. This work adds to the understanding of adaptation of this organism and its mechanisms.

Technical Abstract: The foodborne transmission of Listeria monocytogenes requires physiological adaptation to various conditions, including the cold, osmotic, heat, acid, alkaline, and oxidative stresses, associated with food hygiene, processing, and preservation measures. We review the current knowledge on the molecular stress adaptation responses in L. monocytogenes cells as revealed through transcriptome, proteome, genetic, and physiological analysis. The adaptation of L. monocytogenes to stress exposure is achieved through global expression changes in a large number of cellular components. In addition, the cross-protection of L. monocytogenes exposed to different stress environments might be conferred through various cellular machineries that seem to be commonly activated by the different stresses. To assist in designing L. monocytogenes mitigation strategies for ready-to-eat food products, further experiments are warranted to specifically evaluate the effects of food composition, additives, preservatives, and processing technologies on the modulation of L. monocytogenes cellular components in response to specific stresses.

Last Modified: 12/18/2014
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