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United States Department of Agriculture

Agricultural Research Service

Research Project: GENETIC AND BIOLOGICAL DETERMINANTS OF AVIAN TUMOR VIRUS PATHOGENICITY, TRANSMISSION, AND EVOLUTION

Location: Avian Disease and Oncology Laboratory

Title: Molecular-genetic analysis of field isolates of Avian Leucosis Viruses in the Russian Federation

Authors
item Plotnikov, V -
item Grebennikova, T -
item Yuzhakov, A -
item Dudnikova, E -
item Norkina, S -
item Zaberezhny, A -
item Aliper, T -
item Fadly, Aly

Submitted to: Problems of Virology
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: March 22, 2012
Publication Date: September 10, 2012
Citation: Plotnikov, V.A., Grebennikova, T.V., Yuzhakov, A.G., Dudnikova, E.K., Norkina, S.N., Zaberezhny, A.D., Aliper, T.I., Fadly, A.M. 2012. Molecular-genetic analysis of field isolates of Avian Leucosis Viruses in the Russian Federation. Problems of Virology. 57(5):39-43.

Interpretive Summary: Avian leukosis viruses (ALVs) are economically important poultry viruses that infect chickens causing cancer-like disease and other production problems in affected flocks in various countries around the world. Through collaborative research sponsored by USDA-ARS and U.S. Department of States, USDA-ARS scientists collaborated with colleagues from the Russian Federation and identified ALV infection and tumors in various flocks located in various regions in the Russian Federation. Because of international poultry trade among various countries in the world, identification and characterization of most globally prevalent subtype of ALV is an important factor in designing future diagnostics and control methods if such infection.

Technical Abstract: Commercial poultry farms in 14 regions of Russian Federation were monitored for avian leukosis virus (ALV) infection using virus isolation tests and serology. Results indicated the presence of two subgroups of ALV in farms located in 11 of 14 regions. Analysis of the genomes of 12 field isolates of ALV from these farms revealed that these Russian isolates belong to two subgroups. Differences in DNA sequences between Russian isolates and prototypes of ALV and varied from 5% to 10%.

Last Modified: 7/28/2014