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Title: NIH workshop summary: shaping the development of an iodine research initiative for the U.S.

Author
item SWANSON, CHRISTINE - National Institutes Of Health (NIH)
item ZIMMERMAN, MICHAEL - Eth Zurich
item SKEAFF, SHEILA - University Of Otago
item PEARCE, ELIZABETH - Boston University Medical School
item DWYER, JOHANNA - National Institutes Of Health (NIH)
item TRUMBO, PAULA - Food And Drug Administration(FDA)
item ZEHALUK, CHRISTINA - Health Canada
item ANDREWS, KAREN - Johns Hopkins School Of Public Health
item CARRIQUIRY, ALICIA - Iowa State University
item CALDWELL, KATHLEEN - Centers For Disease Control And Prevention (CDC) - United States
item EGAN, S - Food And Drug Administration(FDA)
item LONG, STEPHEN - National Institute Of Standards & Technology (NIST)
item BAILEY, REGAN - National Institutes Of Health (NIH)
item SULLIVAN, KEVIN - Centers For Disease Control And Prevention (CDC) - United States
item Holden, Joanne
item BETZ, JOSEPH - National Institutes Of Health (NIH)
item PHINNEY, KAREN - National Institute Of Standards & Technology (NIST)
item BROOKS, STEPHEN - Health Canada
item JOHNSON, CLIFFORD - National Center For Health Statistics
item HAGGANS, CAROL - National Institutes Of Health (NIH)

Submitted to: Journal of Nutrition
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 3/26/2012
Publication Date: 5/2/2012
Citation: Swanson, C.A., Zimmerman, M.B., Skeaff, S., Pearce, E., Dwyer, J.T., Trumbo, P.R., Zehaluk, C., Andrews, K.W., Carriquiry, A., Caldwell, K.L., Egan, S.K., Long, S.E., Bailey, R.L., Sullivan, K.M., Holden, J.M., Betz, J.M., Phinney, K.W., Brooks, S.P., Johnson, C.L., Haggans, C.J. 2012. NIH workshop summary: shaping the development of an iodine research initiative for the U.S. Journal of Nutrition. DOI: 10.3945/jn.111.156448.

Interpretive Summary: The Office of Dietary Supplements (ODS) at NIH sponsored a workshop May 12–13, 2011, to bring together representatives from various NIH Institutes and Centers as a first step in developing an NIH iodine initiative. Iodine is required throughout the life-cycle, but pregnant women and infants are the populations most at risk of deficiency because iodine is required for normal brain development and growth. CDC monitors the iodine status of the population on a regular basis, but the status of the most vulnerable populations remains uncertain. NIH funds very little investigator-initiated research relevant to iodine and human nutrition, but ODS has worked for several years with a number of other U.S. government agencies to develop many of the resources needed to conduct iodine research of high quality (e.g. validated analytical methods and reference materials for multiple types of samples). The Nutrient Data Laboratory (NDL) has assessed the iodine content of selected foods and dietary supplements. Iodine experts, scientists from several U.S. government agencies, and NIH representatives met for 2 days to identify iodine research needs appropriate to the NIH mission. At the iodine workshop, NDL presented analytical results for iodine in 55 over-the-counter prenatal multivitamins analyzed as part of the Dietary Supplement Ingredient Database project. NDL also has initiated a pilot study to evaluate new analytical methods for the analysis of iodine in foods expected to be major contributors of iodine to the U.S. diet.

Technical Abstract: The Office of Dietary Supplements (ODS) at NIH sponsored a workshop May 12–13, 2011, to bring together representatives from various NIH Institutes and Centers as a first step in developing an NIH iodine initiative. The workshop also provided an opportunity to identify research needs that would inform the DRI, last revised in 2001. Iodine is required throughout the life-cycle, but pregnant women and infants are the populations most at risk of deficiency because iodine is required for normal brain development and growth. CDC monitors the iodine status of the population on a regular basis, but the status of the most vulnerable populations remains uncertain. NIH funds very little investigator-initiated research relevant to iodine and human nutrition, but ODS has worked for several years with a number of other U.S. government agencies to develop many of the resources needed to conduct iodine research of high quality (e.g. validated analytical methods and reference materials for multiple types of samples). The Nutrient Data Laboratory (NDL) has assessed the iodine content of selected foods and dietary supplements. Iodine experts, scientists from several U.S. government agencies, and NIH representatives met for 2 days to identify iodine research needs appropriate to the NIH mission. At the iodine workshop, NDL presented analytical results for iodine in 55 over-the-counter prenatal multivitamins analyzed as part of the Dietary Supplement Ingredient Database project. To evaluate the variability of iodine in selected foods that are important sources of iodine and to evaluate new analytical methods, NDL also has initiated a pilot study of the iodine content of these foods, including milk, bread, and breakfast cereals. At present, no decision has been made to develop a full food composition table for iodine to assess intake using NHANES data.