Page Banner

United States Department of Agriculture

Agricultural Research Service

Research Project: CONTROL OF FUMONISIN MYCOTOXIN CONTAMINATION IN MAIZE THROUGH ELUCIDATION OF GENETIC AND ENVIRONMENTAL FACTORS ... METABOLISM IN FUSARIUM

Location: Bacterial Foodborne Pathogens & Mycology Research Unit

Title: Influence of water activity on fumonisin and bikaverin gene expression and toxin production in fusarium verticillioides

Authors
item Lazzaro, Irene -
item Busman, Mark
item Battilani, Paola -
item Butchko, Robert

Submitted to: International Society for Plant Pathology
Publication Type: Abstract Only
Publication Acceptance Date: September 14, 2011
Publication Date: September 14, 2012
Citation: Lazzaro, I., Busman, M., Battilani, P., Butchko, R.A. 2012. Influence of water activity on fumonisin and bikaverin gene expression and toxin production in fusarium verticillioides. Italian Society for Plant Pathology.

Technical Abstract: Fusarium verticillioides is known as the main cause of ear rot disease in maize. It can produce a variety of secondary metabolites including fumonisins (FUM) and bikaverin (BIK). The former are toxins known to cause diseases and cancers in both animals and humans; the latter is a red-pigment with defence activity for the fungus itself. Water activity (aw) is one of the main environmental factors known to influence secondary metabolite production in filamentous fungi. The biosynthetic pathways of these metabolites are under study; however the conditions at which genes regulating the pathways are activated are not clearly understood. In this work, we studied the production of both FUM and BIK and the expression of 4 FUM genes and BIK1 in 2 F. verticillioides strains in relation to changing of aw. We further confirmed the relationship between the expression of both FUM and BIK genes under FUM-inducing conditions.

Last Modified: 9/22/2014