Technical Abstract: Breeders and processors are always looking for rapid and accurate methods to evaluate wheat quality. A rapid small-scale hybrid sedimentation method was developed for predicting breadmaking quality of breeders samples by combining the sodium dodecyl-sulfate (SDS) sedimentation method (AACC 56-70) and solvent retention capacity (SRC) test method (AACC 56-11). A preliminary test of the hybrid SDS-SRC method was performed on eight hard winter wheat (HWW) varieties and compared to AACC (56-70) and in-house Hard Winter Wheat Quality Laboratory (HWWQL) methods to show proof of concept. Further validation of the hybrid method was conducted on a diverse set of 53 HWW varieties. The hybrid method was performed in 66% less time than AACC Method 56-70 and HWWQL methods. Furthermore, sample size was reduced from 6 g for the AACC method to 1 g for the hybrid method. The hybrid method exhibited a higher correlation to bread loaf volume (r = 0.84) compared to the AACC method (r > 0.42) and HWWQL method (r = 0.64) for wheat flour. Due to enhanced speed, accuracy, and simplicity, the hybrid SDS-SRC sedimentation method may prove useful in breeding programs and other scenarios where rapid assessment of end-use quality determination is required.