Technical Abstract: The recent trend of increasing concentrations of greenhouse gases (GHGs) in the atmosphere has led to an elevated concern and urgency to adopt effective measures for carbon (C) sequestration to mitigate the climate change. Among all GHGs, carbon dioxide (CO2) is most important one with the greatest concentration and strongest radiative forcing among all. Reducing the release of CO2 to the atmosphere through “green energy” technologies or fossil fuel energy alternatives, such as wind, solar and hydraulic energies, is a major challenge. However, removal of atmospheric CO2 by terrestrial ecosystems via C sequestration and converting the sequestered C into the soil organic C has provided a great opportunity with a promising potential for mitigation of GHG emission and climate change. Soil is an ideal reservoir for storage of organic C since soil organic C has been depleted from land misuse and inappropriate management of soil through the long history. To optimize the efficiency and effectiveness in C sequestration in agriculture, cropping systems such as crop rotation, intercropping, cover cropping, etc., play critical role by influencing optimal yield, total organic C sequestered with biomass accumulation and that remained in the soil. Indeed, there are multiple benefits of soil C sequestration. It can restore the degraded soil, enhance the land productivity, improve the diversity, protect the environment and reduce atmospheric CO2, thus, enhances migration of climate change.