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United States Department of Agriculture

Agricultural Research Service

Research Project: DEVELOPMENT AND PREVENTION OF CHILDHOOD OBESITY

Location: Children's Nutrition Research Center

Title: Rectal ulcer with an elusive diagnosis: all that ulcers is not Crohn disease

Authors
item Jain, Ajay Kumar -
item Motil, Kathleen -
item Abramson, Stuart -
item Han, Yong -
item Tatevian, Nina -

Submitted to: Journal of Pediatric Gastroenterology and Nutrition
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: October 26, 2009
Publication Date: September 1, 2010
Citation: Jain, A., Motil, K., Abramson, S., Han, Y., Tatevian, N. 2010. Rectal ulcer with an elusive diagnosis: all that ulcers is not Crohn disease. Journal of Pediatric Gastroenterology and Nutrition. 51(3):367-369.

Interpretive Summary: A single rectal ulcer is an uncommon finding in children with gastrointestinal disease. We described a patient with primary leukocyte adhesion deficiency (LAD) who presented with a fever, rash, and a rectal ulcer. Although inflammatory bowel disease (IBD) is foremost among the differential diagnoses, a primary immunological defect such as leukocyte adhesion deficiency should not be forgotten because of the different approach to intervention. As a result of our work, we are now aware that all ulcers should not be considered as correlated with inflammatory bowel disease.

Technical Abstract: A single rectal ulcer is an uncommon finding in children with gastrointestinal disease. Although inflammatory bowel disease (IBD) is foremost among the differential diagnoses, a primary immunological defect should not be forgotten. Because of the paucity of literature on the association of rectal ulcers and immunodeficiency disorders, we described a patient with primary leukocyte adhesion deficiency (LAD) who presented with a fever, rash, and a rectal ulcer.

Last Modified: 4/20/2014
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