Technical Abstract: “Crooked calf disease” is used to describe a number of skeletal malformations in newborn calves, including a twisted spine, neck, and one or both forelimbs. These malformations develop when the pregnant cow eats toxic lupines containing the alkaloids anagyrine, ammodendrine, and N-methyl ammodendrine between gestation days of 40-100. Cleft palate has also been identified as part of the syndrome. Cleft palate is induced during days 40-50 of gestation. The skeletal malformations and cleft palate often results in death of calves. Cows pregnant with severely deformed calves often experience difficult births and require caesarian section or veterinarian assistance for delivery. In this report, we document reported incidences of crooked calf disease and provide information to help ranchers with toxic lupine species make informed breeding and grazing management decisions.