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Title: Bioavailability of veterinary antibiotics in surface water

Author
item HENDERSON, KERI - IA STATE UNIVERSITY
item Moorman, Thomas
item COATS, JOEL - IA STATE UNIVERSITY

Submitted to: American Chemical Society Abstracts
Publication Type: Abstract Only
Publication Acceptance Date: 3/29/2007
Publication Date: 3/29/2007
Citation: Henderson, K., Moorman, T.B., Coats, J. 2007. Bioavailability of veterinary antibiotics in surface water [abstract]. American Chemical Society Abstracts, AGRO. p. 85.

Interpretive Summary:

Technical Abstract: Veterinary antibiotics are commonly used as feed additives in livestock production for growth promotion and disease prevention. These pharmaceuticals are often excreted by the livestock in urine and feces, and enter the environment via manure application. Little is known about the fate of veterinary antibiotics in terrestrial and aquatic ecosystems. Understanding the bioavailability of pharmaceuticals in environmental matrices is particularly important considering they are often in an active form. In this study, the bioavailabilities of radiolabeled erythromycin and sulfamethazine in water microcosms were evaluated using C8-Empore extraction disks as passive sampling devices, and Lumbriculus variegatus in a bioassay. The disks and worms were incubated in treated water at several time points. At the end of the study, the disks and worms were extracted, and amount of radioactivity was determined, and compared to levels in the water to determine bioaccumulation.