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ARS Home » Northeast Area » Boston, Massachusetts » Jean Mayer Human Nutrition Research Center On Aging » Research » Publications at this Location » Publication #200441

Title: Assessment of usual dietary intake in population studies of gene-diet interaction

Author
item Tucker, Katherine

Submitted to: Nutrition Metabolism and Cardiovascular Disease
Publication Type: Review Article
Publication Acceptance Date: 7/31/2006
Publication Date: 2/15/2007
Citation: Tucker, K. 2007. Assessment of usual dietary intake in population studies of gene-diet interaction. Nutrition Metabolism and Cardiovascular Disease. 17(2): 74-81.

Interpretive Summary:

Technical Abstract: Dietary intake is a critical exposure when examining genetic factors on disease risk. Weighed diet records can provide the most accurate assessment of intake, but are usually not realistic in large population studies. Multiple 24 hour dietary recalls provide detail, allowing for diverse dietary practices, but are costly. Food frequency questionnaires are the most cost effective tool for assessing usual intake, particularly for micronutrients with high day to day variability, but recent studies question their ability to measure macronutrient intakes for assessing diet and disease relationships. Care must be taken to ensure that the questionnaire is appropriate for all major subsets of the target population. Multiple recalls should be considered when macronutrient intake is of primary interest. Continued efforts to improve dietary assessment methodology must be investigated.