Author
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Darwish, Ahmed |
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Submitted to: Annual Eastern Fish Health Workshop
Publication Type: Abstract Only Publication Acceptance Date: 3/27/2006 Publication Date: 3/27/2006 Citation: Darwish, A.M. 2006. Laboratory efficacy of florfenicol against Streptococcus iniae infection in sunshine bass. 31st Annual Eastern Fish Health Workshop. p.1. Interpretive Summary: Technical Abstract: An experimental feeding trial was performed to evaluate the efficacy of florfenicol (FF) in controlling Streptococcus iniae infection in sunshine bass (SB). Doses of FF tested were 0, 5, 10, 15 and 30 mg active ingredient per kilogram of fish body weight (BW) per day. Administration of medicated feed started within 22-24 h post challenge by waterborne exposure to virulent S. iniae. The FF medication was continued for 10 consecutive days, followed by a 25 d post treatment observation. Oral administration of FF medicated feed for 10 d at 5, 10, 15 and 30 mg FF/ BW/d significantly increased (P<0.05) the survival of S. iniae infected SB from 4.2 % in the challenged non-medicated positive control group to 69.2, 86.7, 94.2 and 94.2 %, respectively. The survival rate was significantly higher in the 15 and 30 mg treatments (94.2 and 94.2 %, respectively) than the 5 mg treatment (69.2) but there was no significant difference among the treatments 10 mg and higher. At the conclusion of the experiment no carriers were detected in any challenged group receiving FF medicated diet while the bacterium was recovered from the non-medicated challenged survivors of the infection. |
