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ARS Home » Northeast Area » Boston, Massachusetts » Jean Mayer Human Nutrition Research Center On Aging » Research » Publications at this Location » Publication #193074

Title: MAJOR MOBILITY DISABILITY-ASSESSMENT AND BASELINE PERFORMANCE IN LIFE

Author
item NEWMAN, ANNE - UNIV PITTSBURGH SCH MED
item Fielding, Roger
item KRITCHEVSKY, STEPHEN - WAKE FOREST UNIVERSITY
item PRUITT, LESLIE - STANFORD UNIVERSITY
item DUNN, ANDREA - COOPER INSTITUTE

Submitted to: Gerontological Society of America
Publication Type: Abstract Only
Publication Acceptance Date: 11/18/2005
Publication Date: 12/1/2005
Citation: Newman, A., Fielding, R.A., Kritchevsky, S., Pruitt, L., Dunn, A. 2005. Major mobility disability-assessment and baseline performance in life. Gerontological Society of America.45:42.

Interpretive Summary:

Technical Abstract: Major mobility disability has previously been defined by self-reported inability to walk ¼ mile. Observed inability to walk 400 meters provides a valid and objective disability endpoint for clinical trials that is relevant to community walking, future advanced disability and mortality. LIFE participants with a Short Physical Performance Battery (SPPB) score <10/12 were asked to walk 400 meters at baseline. Of 1253, 129 (10.3%) were unable to complete the task and were excluded from randomization to intervention. Walking ability was related to SPPB score. In those with SPPB <7, 24.5% were unable, for SPPB 7-8, 9.7% were unable and for SPPB of 9, 2.0% were unable to walk 400 meters (p=<0.0001). Walking ability will be reassessed every 6 months. Incidence will be defined as first onset of inability to walk 400 meters. Major mobility disability rates will be used to define the sample size for a larger trial.