Author
NEWMAN, ANNE - UNIV PITTSBURGH SCH MED | |
Fielding, Roger | |
KRITCHEVSKY, STEPHEN - WAKE FOREST UNIVERSITY | |
PRUITT, LESLIE - STANFORD UNIVERSITY | |
DUNN, ANDREA - COOPER INSTITUTE |
Submitted to: Gerontological Society of America
Publication Type: Abstract Only Publication Acceptance Date: 11/18/2005 Publication Date: 12/1/2005 Citation: Newman, A., Fielding, R.A., Kritchevsky, S., Pruitt, L., Dunn, A. 2005. Major mobility disability-assessment and baseline performance in life. Gerontological Society of America.45:42. Interpretive Summary: Technical Abstract: Major mobility disability has previously been defined by self-reported inability to walk ¼ mile. Observed inability to walk 400 meters provides a valid and objective disability endpoint for clinical trials that is relevant to community walking, future advanced disability and mortality. LIFE participants with a Short Physical Performance Battery (SPPB) score <10/12 were asked to walk 400 meters at baseline. Of 1253, 129 (10.3%) were unable to complete the task and were excluded from randomization to intervention. Walking ability was related to SPPB score. In those with SPPB <7, 24.5% were unable, for SPPB 7-8, 9.7% were unable and for SPPB of 9, 2.0% were unable to walk 400 meters (p=<0.0001). Walking ability will be reassessed every 6 months. Incidence will be defined as first onset of inability to walk 400 meters. Major mobility disability rates will be used to define the sample size for a larger trial. |