Skip to main content
ARS Home » Plains Area » Clay Center, Nebraska » U.S. Meat Animal Research Center » Livestock Bio-Systems » Research » Publications at this Location » Publication #192380
Title: AN INTEGRATED BAC PHYSICAL MAP OF THE PIG GENOME AND SELECTION OF THE MINIMUM TILEPATH

Author
item HUMPHRAY, SEAN - SANGER INST, CAMBRIDGE UK
item SCOTT, CAROL - SANGER INST, CAMBRIDGE UK
item CLARK, RICHARD - SANGER INST, CAMBRIDGE UK
item MARRON, BRANDY - UNIV ILLINOIS, URBANA
item PLUMB, ROBERT - SANGER INST, CAMBRIDGE UK
item ROGATCHEVA, MARGARITA - UNIV ILLINOIS, URBANA
item MILAN, DENIS - INRA, TOLOSAN, FRANCE
item CHARDON, PATRICK - INRA, JOUY EN JOSAS, FRAN
item Rohrer, Gary
item Nonneman, Danny - Dan
item DE JONG, PIETER - BACPAC RESOURCES, OAKLAND
item MEYERS, STACY - UNIV ILLINOIS, URBANA
item BENDER, CLARE - SANGER INST, CAMBRIDGE UK
item ARCHIBALD, ALAN - ROSLIN INST, ROSLIN, UK
item BEEVER, JONATHON - UNIV ILLINOIS, URBANA
item SCHOOK, LAWRENCE - UNIV ILLINOIS, URBANA
item ROGERS, JANE - SANGER INST, CAMBRIDGE UK

Submitted to: Plant and Animal Genome Conference Proceedings
Publication Type: Abstract Only
Publication Acceptance Date: 12/1/2005
Publication Date: 1/14/2006
Citation: Humphray, S., Scott, C., Clark, R., Marron, B., Plumb, R., Rogatcheva, M., Milan, D., Chardon, P., Rohrer, G.A., Nonneman, D.J. 2006. An integrated BAC physical map of the pig genome and selection of the minimum tilepath. Plant and Animal Genome Conference Proceedings. Poster #W237. p. 60.

Interpretive Summary: No interpretive summary required.

Technical Abstract: We have constructed a physical map of the pig genome by integrating restriction fingerprints and BAC end sequences generated from 4 BAC libraries with radiation hybrid markers, and contig alignments to the human genome. The map provides coverage across the 18 pig autosomes and the X chromosome in 176 contigs as well as localised representation of the gene rich regions on Y. The map is accessible through WebFPC (http://www.sanger.ac.uk/Projects/S_scrofa/WebFPC/porcine/large.shtml) and represents an entry point for rapid electronic positional cloning of genes and fine mapping of QTLs. The map provides a platform for the selection of an efficient minimum tilepath through the genome to support clone-based sequencing and targeted functional genomics studies.