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ARS Home » Northeast Area » Boston, Massachusetts » Jean Mayer Human Nutrition Research Center On Aging » Research » Publications at this Location » Publication #145161
Title: IS IL12B A POTENTIAL GENETIC TARGET FOR THE PREVENTION OF TYPE 1 DIABETES THROUGH DIETARY INTERVENTION?

Author
item ORDOVAS, JOSE - HNRCA
item QI, LU - HNRCA
item SHEN, HAIQING - HNRCA

Submitted to: Nutrition Reviews
Publication Type: Review Article
Publication Acceptance Date: 4/17/2002
Publication Date: 6/1/2002
Citation: Ordovas, J.M., Qi, L., Shen, H. 2002. Is IL12b a potential genetic target for the prevention of type 1 diabetes through dietary intervention? Nutrition Reviews. 60(6):182-186. Review

Interpretive Summary:

Technical Abstract: Type 1 diabetes mellitus (T1D) results from decreased insulin production. Its clinical expression is the result of an array of genetic and environmental factors. The IL12B gene could be one of the loci implicated in the genetic susceptibility of T1D. Thus, this genetic predisposition could be modulated by dietary factors. However, there is no consistency among populations in relation to relevance of this locus as a candidate gene for T1D.