Author
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Gimeno, Isabel |
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Submitted to: International Seminar of Avian Pathology
Publication Type: Proceedings Publication Acceptance Date: 5/26/2002 Publication Date: N/A Citation: N/A Interpretive Summary: Technical Abstract: Marek's disease virus has evolved toward greater forms of virulence within the last 50 years. The two consequences of such evolution to the poultry industry are the more complicated diagnosis and the lower protection conferred by the currently available vaccines. Diagnosis of Marek's disease has become difficult because the emerging more virulent viruses are able to induce the disease in a broader spectrum of host and age and also are able to induce a variety of non-neoplastic syndromes such as acute transient paralysis, lymphodegenerative disease in the lymphoid organs and persistent neurological disease. How these more virulent strains of Marek's disease virus are able to break the immunity conferred by the current available vaccines is poorly understood. However, it is a fact that the most recently isolates are able to induce the disease in chickens that have been vaccinated with bivalent vaccines (serotypes 2 and 3) or even with Rispens. The developing of new more efficient vaccines is thus a need in a short term. Control of Marek's disease cannot be based only on vaccination and both biosecurity and genetic need to consider as well. An update of the characteristics of the disease to consider in the diagnosis of Marek's disease and an overview of the present and future in the control of Marek's disease is presented in this paper. |
