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ARS Home » Midwest Area » Madison, Wisconsin » Vegetable Crops Research » Research » Publications at this Location » Publication #132578

Title: DNA SEQUENCE OF THE YEDK GENE WITHIN THE TABTOXIN BIOSYNTHETIC GENE CLUSTER OF PSEUDOMONAS SYRINGAE

Author
item KINSCHERF, THOMAS - UNIVERSITY OF WISCONSIN

Submitted to: Genbank
Publication Type: Other
Publication Acceptance Date: 3/7/2002
Publication Date: 3/7/2002
Citation: N/A

Interpretive Summary:

Technical Abstract: The predicted gene product of the P. syringae gene is similar to the yedK gene of Escherichia coli (accession:NP 288392) and the 'Gyfsy-2' prophage in Salmonella typhimiurium (accession: NP 460027). The gene also contains significant identity to similar gene in Pseudomonas syringae pv. pisi (accession:CAB96973). Members of this gene family are found widely distributed across taxa of all three Domains. The presence of the a phage associated gene next to the tabtoxin biosynthetic cluster, strongly suggest a mechanism for the horizontal transfer and integration of the tabtoxin pathogenicity island. This mechanism entails the transfer of the region via wide-host range plasmids or bacterial conjugation followed by the integration of the entire tabtoxin biosynthetic cluster as a unit using a phage-like integrase.