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United States Department of Agriculture

Agricultural Research Service

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Research Project: Duration of Salmonella Infection Within Lymph Nodes

Location: Food and Feed Safety Research

Project Number: 6202-32000-030-63
Project Type: Reimbursable

Start Date: Dec 01, 2012
End Date: May 31, 2013

Objective:
To characterize the duration of infection of various serovars and variants of Salmonella within peripheral lymph nodes of cattle following intradermal inoculation.

Approach:
Following successful models developed within the Salmonella Working Group, we will enroll 36 animals and transdermally inoculate various serovars and variants (i.e., clade A versus clade B). At nine time points, calves will be harvested and Salmonella presence evaluated both qualitatively and quantitatively. Prior to strain selection, consultation will occur within the Salmonella Working Group. Various models (such as survival analysis and stochastic simulation) will be used to estimate duration of infection.

Last Modified: 9/21/2014
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