Project Number: 6205-32000-031-39
Project Type: Nonfunded Cooperative Agreement

Start Date: Jul 01, 2012
End Date: Aug 31, 2014

Objective:
Generate research data through collaborative effort: obtain limited use permit for experimental Bm86-based veterinary biological product from APHIS Center for Veterinary Biologics, and perform Cattle Fever Tick Eradication Program.

Approach:
Studies will be planned and executed according to APHIS Center for Veterinary Biologics General Licensing Considerations for Efficacy Studies. Cooperator will prepare and provide the ARS two experimental vaccine formulations containing the antigen Bm86 for efficacy testing. Each of the two experimental Bm86-based vaccines will be tested for efficacy against Rhipicephalus annulatus and R. microplus by the Cattle Fever Tick Research Laboratory. Studies will be reported according to APHIS Center for Veterinary Biologics General Licensing Considerations for Efficacy Studies.