Start Date: Feb 01, 2012
End Date: Jan 31, 2013
Angus beef calves raised under production conditions will be vaccinated with a commercial bovine viral diarrhea virus (BVDV) vaccine. Calves with low, mid range, or high levels of serum neutralizing antibodies following vaccination will be selected. Selected calves will be transferred to the National Animal Disease Center and challenged with a high virulence BVDV. This will be done to determine the level of neutralizing antibodies required for protection.