Project Number: 6645-41000-007-08
Project Type: Nonfunded Cooperative Agreement

Start Date: Feb 01, 2011
End Date: Jan 31, 2014

Objective:
To develop and test models for predicting and controlling translational efficiency of gene expression, and to design and carry out experiments to validate model predictions.

Approach:
Computer models will be developed using free energy of ribosome binding as a factor in translational efficiency. Models will be tested with collaborators using recombinant plasmids in Escherichia coli.