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United States Department of Agriculture

Agricultural Research Service

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Research Project: A Novel Approach for Predicting Translational Efficiency for Recombinant Gene Expression

Location: Food Science Research

Project Number: 6645-41000-007-08
Project Type: Nonfunded Cooperative Agreement

Start Date: Feb 01, 2011
End Date: Jan 31, 2015

Objective:
To develop and test models for predicting and controlling translational efficiency of gene expression, and to design and carry out experiments to validate model predictions.

Approach:
Computer models will be developed using free energy of ribosome binding as a factor in translational efficiency. Models will be tested with collaborators using recombinant plasmids in Escherichia coli.

Last Modified: 7/28/2014
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