Location: Animal Parasitic Diseases
Project Number: 8042-32000-098-03
Start Date: Nov 01, 2010
End Date: Nov 01, 2012
This is a multi-year project that is funded by a consortium representing NPB, USDA, universities and private companies. The consortium represents the first-of-its-kind approach to food animal infectious disease research. The objective of this cooperative research project is to assess the genetic basis of pig responses to porcine reproductive and respiratory syndrome virus (PRRSV) infection, an infection which causes pneumonia and growth retardation in pigs, affecting the respiratory mucosa. The project uses a Nursery Pig Model to assess pig resistance/susceptibility to primary PRRSV infection. Results from the first year have affirmed that there are genetic components involved in controlling the effectiveness of pig responses to PRRSV infection. By continuing these studies, the plan is to test a larger number (1,500 total over 4 years) of PRRSV infected pigs. Data collected, using a series of defined assays, stored samples for later work and collated data in the PHGC database will enable researchers to verify important genotypes and phenotypes that predict resistance, tolerance or susceptibility to PRRSV infection.