Project Number: 1245-31000-104-11
Start Date: Aug 19, 2010
End Date: Aug 31, 2013
Software will be developed or adapted for use in annotating whole genome sequence data being generated as part of international collaborations that include ARS, including gene prediction, use of comparative mapping information, and identifying novel genetic markers (polymorphisms) and positional candidate genes. Emphasis should be given to problems specific to post-analysis of the bovine genome sequencing project, as BFGL is leading those efforts and development of tools with wide utility for the community is a priority. Tools will be developed or adopted to quickly identify positional candidate genes from QTL map position integration with signatures of selection, gene expression and breed specific polymorphism information. Methods for comparison of genetic variation in coding genes between sub-species of cattle need to be investigated.