Location: Foreign Animal Disease Research
Project Number: 8064-32000-057-58
Start Date: Aug 15, 2013
End Date: Dec 31, 2016
ARS, PIADC will conduct vaccine matching and sequence and phylogenetic analysis of samples provided by collaborators from NARC. In addition, serological cross-reaction analysis will be carried out and compared to the deduced amino-acid sequence of the P1 region of selected FMDVs. This information will be useful in selecting variants to be used for vaccine formulation. ARS, PIADC staff will travel to Pakistan to implement the vaccine matching protocol at NARC and to aid in performing necropsies of potentially persistent infected Asian buffalo and cattle to study the anatomical pathology of persistence. ARS, PIADC will provide epidemiological information received from Pakistani collaborators to collaborators from UC Davis to populate the Global Bio Portal to provide near-real-time updates to the OIE, USDA APHIS and Pakistani authorities.