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United States Department of Agriculture

Agricultural Research Service

Related Topics

Research Project: Obesity Research in the Lower Mississippi Delta

Location: Mid South Area (MSA)

Project Number: 6401-51000-002-02
Project Type: Specific Cooperative Agreement

Start Date: Sep 01, 2012
End Date: Aug 31, 2015

Objective:
This SCA involves three separate research projects with specific objectives as detailed below: “Obesity Prevention in the Mississipi Delta Region of Mississippi” (1) Evaluate a church-based intervention program “Delta Body and Soul” to increase adherence to Dietary Guidelines for Americans (DGA) diet and physical activity recommendations; and (2) serve as a nutritional consultant in the development, implementation, and evaluation of a project designed to improve maternal and neonatal/infant metabolic health and weight outcomes via education of the mothers. “Dietary Intake Patterns Associated with Excess Adiposity in U.S. Children” Using three dietary pattern identification methods, Healthy Eating Index (HEI) 2005, principal component analysis, and reduced rank regression, determine associations among the dietary pattern scores, excess adiposity, physical activity, and sedentary behavior in 2-18 year old U.S. children using the most recent National Health and Nutrition Examination Survey (NHANES) data. “Maternal Overweight, Delta Health Alliance (DHA) Supplementation, and Iron Status: An Ancillary Study” (1) Evaluate pre-pregnancy Body Mass Index (BMI), pre-pregnancy iron status, perinatal weight gain (current weight - pre-pregnancy weight), inflammation, iron status, serum hepcidin concentrations, and dietary intake in overweight pregnant women at baseline (weeks 17-20 gestation); and assess relationships among these parameters; (2) evaluate perinatal weight gain, inflammation, iron status, and serum hepcidin concentrations in overweight pregnant women at 30 and 36 weeks gestation and at delivery; and assess for differences in parameter changes (from baseline) by supplementation group and relationships among these parameters; (3) evaluate neonatal inflammation, iron status, and serum hepcidin concentration (via cord blood), infant birth weight, and infant Appearance, Pulse, Grimace, Activity, and Respiration (APGAR) score at delivery; and assess for differences in these parameters by supplementation group and for relationships among the parameters; and (4) assess for relationships between maternal and neonatal inflammation, iron status, and serum hepcidin concentrations, and maternal perinatal weight gain at delivery.

Approach:
“Obesity Prevention in the Mississipi Delta Region of Mississippi” Statistical methods will be used to compare changes in diet and physical activity outcomes between the Delta Body and Soul control and intervention participants while accounting for group (church) randomization as well as sociodemographic covariates. An existing education program, Parents as Teachers, will be enhanced to specifically address nutritional prenatal and postnatal topics (e.g. breast-feeding) for mothers and their infants. Statistical methods will also be used to compare health outcomes between mothers and their infants in the standard vs. the enhanced education programs. “Dietary Intake Patterns Associated with Excess Adiposity in U.S. Children” Individual foods consumed by children in the National Health and Nutrition Examination Survey (NHANES) datasets will be assigned to defined food groups based on previous research and investigators’ interest in specific foods. Statistical methods will be used to identify dietary patterns in the NHANES datasets using three different approaches -- Healthy Eating Index (HEI)-2005, principal component analysis, and reduced rank regression. Statistical methods will be used to determine associations among the dietary pattern scores, excess adiposity, physical activity, and sedentary behavior. “Maternal Overweight, Delta Health Alliance (DHA) Supplementation, and Iron Status: An Ancillary Study” Statistical methods will be used to summarize and assess relationships among the parameters listed previously in the Objectives section. Assessments will be performed for baseline (maternal), 30 weeks gestation (maternal), 36 weeks gestation (maternal), and delivery (maternal and infant) parameters. Assessments will also be performed for within supplement group and between supplement group changes.

Last Modified: 7/30/2014
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