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United States Department of Agriculture

Agricultural Research Service

Research Project: Effects of Defense Peptides on Fusarium Head Blight Project Number: 0500-00053-003-51
Project Type: Grant

Start Date: Jun 25, 2012
End Date: Jun 24, 2015

Objective:
Apply newly developed plant defense technologies to the protection of wheat from scab caused by Fusarium species. Technologies include, methods for selection of peptides that bind to and disrupt the development of infective structures of invasive pathogens, and means of delivering disruptive peptides in transgenic plants via fusion to a scaffold protein.

Approach:
Select peptides that bind to pathogen structure from combinational libraries of one billion or more random peptide sequences. Evaluate the ability of recovered binding peptides to inhibit germination and growth of F. graminearum macroconidia and germlings representative of diverse isolates.

Last Modified: 7/28/2014
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