2012 Annual Report 1a.Objectives (from AD-416): The purpose of this agreement is to study and monitor the effects of analytical characteristics of dietary components on health. The study will investigate the role of food and dietary supplements intake patterns, food preparation methods, and/or food and dietary supplements components in human health, primarily related to chronic disease outcomes such as hypertension, diabetes, and obesity. The Cooperator has expertise in human research and dietary patterns associated with chronic disease. 1b.Approach (from AD-416): Data for nutrients and other components in foods and/or dietary supplements that are needed to support application of U.S. Dietary Guidelines for Americans by consumers and others will be periodically updated. Food and dietary supplement composition will be monitored through sampling and analysis as well as literature review. Development of databases may also be involved. The Cooperator will provide expertise in skills needed in food composition, methods, and database development. 3.Progress Report: This agreement was created to support the development of the Expanded USDA Flavonoid Databases for the Assessment of Dietary Intakes and a database for the estimation of the intake of 30 flavonoid components. The project is a collaborative effort between the Nutrient Data Laboratory (NDL) and the Food Surveys Research Group (FSRG). USDA’s databases on the flavonoid content of selected foods were expanded to include full profiles for six subclasses (flavanols, flavonols, flavones, flavanones and anthocyanidins plus isoflavones) for ~2,900 food items included in Food and Nutrient Database for Dietary Studies (FNDDS) 4.1 and used in National Health and Nutrition Examination Survey (NHANES) 2007-08. Analytical values were taken from Release 3.1 of the flavonoid database and Release 2.0 of the isoflavones database. Release 3.0 of the flavonoid database was updated during FY2012 to correct a few values and add some additional food items to create Release 3.1. Other values needed for the expanded database were calculated from the analytical values or assigned an assumed “0”. The data will be used in the investigation of the relationship between dietary intakes of flavonoids and health benefits through epidemiological studies. The expanded flavonoid database was delivered to FSRG in early July 2012.