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United States Department of Agriculture

Agricultural Research Service

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Research Project: A Novel Approach for Predicting Translational Efficiency for Recombinant Gene Expression

Location: Food Science Research

Project Number: 6070-41000-008-08
Project Type: Nonfunded Cooperative Agreement

Start Date: Feb 01, 2011
End Date: Jan 31, 2016

To develop and test models for predicting and controlling translational efficiency of gene expression, and to design and carry out experiments to validate model predictions.

Computer models will be developed using free energy of ribosome binding as a factor in translational efficiency. Models will be tested with collaborators using recombinant plasmids in Escherichia coli.

Last Modified: 12/1/2015
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