Project Number: 1940-32000-057-17
Project Type: Trust

Start Date: Oct 01, 2010
End Date: Sep 30, 2012

Objective:
This cooperative research project focuses on the study of the pathogenicity of Foot-and-Mouth Disease Virus (FMDV) Korean isolates, A/ROK/2010 and O/ROK/2010 in pigs and cattle. Specific objectives are: 1. Conduct a time-course study of FMD infection in pigs and cattle; including direct transmission, 2. Obtain and catalog quality pictures of lesions and reference stocks of research material; serum and tissues.

Approach:
NVRQS will provide FMDV A/ROK/2010 and O/ROK/2010 from pigs and cattle, as well as conduct epidemiological analysis and conduct genomic sequencing of viral isolates. ARS, PIADC will conduct FMDV pathogenicity studies on swine and cattle; inclusive of time-course study and histopathological evaluation and sample collection. NVRQS scientists will be trained to conduct research on FMDV pathogenesis using methology developed by ARS, PIADC scientists. Data generated will help to develop and upgrade current diagnostic assays for the detection of FMD circulating in south east Asia.