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United States Department of Agriculture

Agricultural Research Service

Related Topics

Research Project: Global Health and Environmentally-Induced Birth Defects: Biomarkers and Mechanisms of Gestational Fumonisin Exposure and Neural Tube Defects

Location: Toxicology and Mycotoxin Research

Project Number: 6040-42000-012-01
Project Type: Reimbursable

Start Date: Sep 27, 2010
End Date: Aug 31, 2014

Objective:
Determine the role of fumonisin exposure in the high incidence of neural tube defects (NTDs) in consumers of maize products.

Approach:
Utilize information developed from Creighton University studies in mouse models to assess and validate the use of sphingolipid and genetic mechanism-based and fumonisin exposure-based biomarkers in women from populations known to consume large amounts of maize potentially contaminated with fumonisin.

Last Modified: 12/22/2014
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