Location: Plant Polymer Research
2012 Annual Report
Regular meetings between the staff at ARS and ISU will be held to discuss experiments and results. After both parties design an experiment, ISU scientists will perform the experiments and report the results to the ARS staff. Analysis of the results and their implications to the system under study will be discussed. Results and analysis will be presented at meetings, and/or published in peer-reviewed journals.
1)Dynamic light scattering was used to measure the size of small spheres made with starch or biodegradable polymers based on lactide and glycoside. These are currently being used to embed photosensitizers to be delivered to blood parasites that cause the disease leishmaniasis. Using nanoprecipitation fluidics, homogeneous particles with a size average of ~200 nm were produced..
2)Reverse microemulsion polymerization methodology is being developed to produce starch particles loaded with photosensitizers. Starch is crosslinked using phosphorous oxichloride. The size of the particles depends on the emulsification conditions, but we have been able to obtain particles with average size of about 200 nm, although the samples exhibit large polydispersion. Drawbacks have been mostly related to the solvent partitioning of the compound into the emulsion..
3)The instrument has been used successfully to assure the size reproducibility of the preparations as well as the size distribution of the particles..
4)Finally, the instrument provided by National Center for Agricultural Utilization Research (NCAUR), Plant Polymer Research (PPL) has been used to obtain the molecular weight of a dextrin sample using conventional light scattering techniques.