Project Number: 5430-32000-006-05
Project Type: Specific Cooperative Agreement

Start Date: Sep 01, 2010
End Date: Aug 31, 2015

Objective:
To develop knowledge, diagnostic tools, and control practices and technology to address the threat posed to the U.S. Pork Industry by Classical Swine Fever (CSF), African Swine Fever (ASF) and of other diseases of high consequence.

Approach:
Classical Swine Fever (CSF) and African Swine Fever (ASF) are highly infectious diseases of swine. As foreign animal diseases (FADs), an outbreak of CSF, ASF or an unknown threat would significantly affect the U.S. pork industry and export markets. Improved CSF marker live-attenuated vaccines are needed to further reduce the risk posed by this FAD. There are no commercial ASF vaccines, which is a significant gap in the available interventions to stop the spread of ASF. Furthermore, there is a gap in our understanding on the mechanism of ASF pathogenesis. Other needs include improved diagnostic approaches for conducting surveillance. Underlying this research is improved diagnostics and surveillance.