Mode of Action of Antidiabetic Activity, Identification of Bioactive Compound and Micropropagation of Serviceberry (Amelanchier Alnifolia)
Natural Products Utilization Research
2010 Annual Report
1a.Objectives (from AD-416)
1. Identify mechanisms that mediate anti-diabetic effects of serviceberry extracts.
2. Isolate and identify the anti-diabetic constituent(s) from serviceberry.
3. Develop a robust micropropagation system for rapid germplasm multiplication, maintenance and storage.
4. Develop efficient organic production systems for serviceberry cultivation.
1b.Approach (from AD-416)
ARS contact scientist will identify anti-diabetic constituents from serviceberry through activity-guided fractionation using an assay that will be conducted at Auburn University, another collaborator in this project. ARS scientist will use various spectroscopic methods to identify the anti-diabetic constituent(s).
The objective of the project is to isolate and identify the anti-diabetic constituent(s) from serviceberry. This is a multi-institutional collaboration which also includes Alabama A&M University and Auburn University. Work on this project has not started. There have been delays in completing transfer of funds to Auburn University where antidiabetic testing is to be done. Bioassay-guided isolation will be started as soon as collaborator at Auburn University is ready. Methods used for monitoring or discussing research progress were by telephone call and email.