2012 Annual Report 1a.Objectives (from AD-416): The objective of this work is to assess disease resistance in wheat accessions from the National Small Grains Collection to diseases of increasing importance in U.S. wheat production. 1b.Approach (from AD-416): Key accessions from the NSGC are being genotyped using DArT marker technology and SSR markers. These materials will be tested at North Dakota State University for resistance to important wheat diseases including bacterial leaf streak, Stagonospora nodorum blotch, tan spot, and Septoria tritici blotch. An association genetics approach will be taken to search for relationships between markers and disease resistance. Disease resistance data will be reported to the Germplasm Resources Information Network for dissemination to the plant breeding community. 3.Progress Report: The National Small Grains Collection is a source of building blocks used by plant breeders to create new small grains varieties for farmers. Knowing which accessions in the collection are resistant to key diseases is valuable information for breeders. Over the two years of the project we identified new sources of resistance to important wheat diseases, including tan spot, Stagonospora nodorum blotch, spot blotch, and Septoria tritici blotch. These materials will be useful for developing new, disease resistant, wheat varieties. The results relate to Objective 2 of the parent project, “Strategically evaluate small grains genetic resources for priority biotic and abiotic stress resistance.”