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United States Department of Agriculture

Agricultural Research Service

Research Project: USING NUTRITION AND PROTEOLYSIS TO DELAY AGE RELATED MACULAR DEGENERATION AND CATARACTS

Location: Human Nutrition Research Center on Aging

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)

The relationship of major American dietary patterns to age-related macular degeneration - (Peer Reviewed Journal)
Chiu, C., Chang, M., Zhang, F., Li, T., Gensler, G., Schleicher, M., Taylor, A. 2014. The relationship of major American dietary patterns to age-related macular degeneration. American Journal of Optthalmology. 158(1):118-128.
High glucose activates ChREBP-mediated HIF-1a and VEGF expression in human RPE cells under normoxia - (Book / Chapter)
Chang, M., Chiu, C., Shang, F., Taylor, A. 2014. High glucose activates ChREBP-mediated HIF-1a and VEGF expression in human RPE cells under normoxia. IN: Lambris, J.D., Cohen, I.R., Lajtha, A., Paoletti, R. Advances in Experimental Medicine and Biology. Springer, New York. 801:609-621.
Nutritional modulation of cataract - (Review Article)
Weikel, K.A., Garber, C., Baburins, A., Taylor, A. 2014. Nutritional modulation of cataract. Nutrition Reviews. 72(1):30-47.
Cfh genotype interacts with dietary glycemic index to modulate age-related macular degeneration-like features in mice - (Peer Reviewed Journal)
Rowan, S., Weikel, K., Chang, M., Nagel, B.A., Thinschmidt, J.S., Carey, A., Grant, M.B., Fliesler, S.J., Smith, D., Taylor, A. 2014. Cfh genotype interacts with dietary glycemic index to modulate age-related macular degeneration-like features in mice. Investigative Ophthalmology and Visual Science. 55(1):492-501.
Newborn mouse lens proteome and its alteration by lysine 6 mutant ubiquitin - (Peer Reviewed Journal)
Shang, F., Wilmarth, P.A., Chang, M., Liu, K., David, L., Caceres, M., Wawrousek, E., Taylor, A. 2014. Newborn mouse lens proteome and its alteration by lysine 6 mutant ubiquitin. Journal of Proteome Research. 13(3):1177-1789.
Common cell biologic and biochemical changes in aging and age-related diseases of the eye: Toward new therapeutic approaches to age-related ocular diseases - (Literature Review)
Whitcomb, E., Shang, F., Taylor, A. 2013. Common cell biologic and biochemical changes in aging and age-related diseases of the eye: Toward new therapeutic approaches to age-related ocular diseases. Investigative Ophthalmology and Visual Science. 54(14):ORSF31-ORSF36.
Diminishing risk for age related macular degeneration with nutrition: A current view - (Literature Review)
Schleicher, M., Weikel, K., Garber, C., Taylor, A. 2013. Diminishing risk for age related macular degeneration with nutrition: A current view. Nutrients. 5(7):2405-2456.
The ubiquitin conjugating enzyme UbcH7, controls cell migration - (Abstract Only)
Whitcomb, E.A., Lefeuvre, A., Taylor, A. 2013. The Ubiquitin Conjugating Enzyme UbcH7, controls cell migration. Journal of Federation of American Societies for Experimental Biology. 27:785.4.
The ubiquitin conjugating enzyme UbcH10 competes with UbcH3 for binding to the SCF complex, a ubiquitin ligase involved in cell cycle progression - (Abstract Only)
Lefeuvre, A., Afful, D., Shang, F., Taylor, A. 2013. The ubiquitin conjugating enzyme UbcH10 competes with UbcH3 for binding to the SCF complex, a ubiquitin ligase involved in cell cycle progression. Journal of Federation of American Societies for Experimental Biology. 27:1027.7.
A risk score for the prediction of advanced age-related macular degeneration: Development and validation in 2 prospective cohorts - (Peer Reviewed Journal)
Chiu, C., Mitchell, P., Klein, R., Klein, B.E., Chang, M., Gensler, G., Taylor, A. 2014. A risk score for the prediction of advanced age-related macular degeneration: Development and validation in 2 prospective cohorts. Ophthalmology: Journal of The American Academy of Ophthalmology. DOI:10.1016/j.ophtha.2014.01.016.
Mechanistically linking age-related diseases and dietary carbohydrate via autophagy and the ubiquitin proteolytic systems - (Other)
Taylor, A. 2012. Mechanistically linking age-related diseases and dietary carbohydrate via autophagy and the ubiquitin proteolytic systems. Autophagy. 8(9):1404-1406.
Introduction to the issue regarding research regarding age related macular degeneration - (Other)
Taylor, A. 2012. Introduction to the issue regarding research regarding age related macular degeneration. Molecular Aspects of Medicine . 33(4):291-294.
Roles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: implications in the pathogenesis of age-related macular degeneration - (Review Article)
Shang, F., Taylor, A. 2012. Roles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: implications in the pathogenesis of age-related macular degeneration. Molecular Aspects of Medicine. 33(4):446-466. DOI: 10.1016/j.mam.2012.04.001.
Nutritional modulation of age-related macular degeneration - (Review Article)
Weikel, K.A., Taylor, A., Chiu, C. 2012. Nutritional modulation of age-related macular degeneration. Molecular Aspects of Medicine. 33:318-375.
Role of ubiquitin-proteasome in protein quality control and signaling: implication in the pathogenesis of eye diseases - (Book / Chapter)
Shang, F., Taylor, A. 2012. Role of ubiquitin-proteasome in protein quality control and signaling: implication in the pathogenesis of eye diseases. In: Grune, T., editor. Progress in Molecular Biology and Translational Science. Burlington, MA: Academic Press. 109:347-396.
Lutein and zeaxanthin supplementation reduces H202-induced oxidative damage in human lens epithelial cells - (Peer Reviewed Journal)
Gao, S., Qin, T., Liu, Z., Caceres, M., Ronchi, C., Chen, C., Yeum, K., Taylor, A., Blumberg, J., Liu, Y., Shang, F. 2011. Lutein and zeaxanthin supplementation reduces H202-induced oxidative damage in human lens epithelial cells. Molecular Vision. 17:3180-3190.
Associations between genetic polymorphisms of insulin-like growth factor axis genes and risk for age-related macular degeneration - (Peer Reviewed Journal)
Chiu, C., Conley, Y., Gorin, M., Gensler, G., Lai, C., Shang, F., Taylor, A. 2011. Associations between genetic polymorphisms of insulin-like growth factor axis genes and risk for age-related macular degeneration. Investigative Ophthalmology and Visual Science. 52(12):9099-9107.
Glycation-altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age-related disease in non diabetics - (Peer Reviewed Journal)
Uchiki, T., Weikel, K.A., Jiao, W., Shang, F., Caceres, A., Pawlak, D., Handa, J.T., Brownlee, M., Nagaraj, R., Taylor, A. 2012. Glycation-altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age-related disease in non diabetics. Aging Cell. 11(1):1-13.
Lutein and zeaxanthin supplementation reduces photo-oxidative damage and modulates the expression of inflammation related genes in retinal pigment epithelial cells - (Peer Reviewed Journal)
Bian, Q., Gao, S., Zhou, J., Qin, J., Taylor, A., Johnson, E.J., Tang, G., Sparrow, J.R., Gierhart, D., Shang, F. 2011. Lutein and zeaxanthin supplementation reduces photo-oxidative damage and modulates the expression of inflammation related genes in retinal pigment epithelial cells. Free Radicals in Biology and Medicine. 53(6):1298-1307.
Ubiquitin-proteasome pathway and cellular responses to oxidative stress - (Review Article)
Shang, F., Taylor, A. 2011. Ubiquitin-proteasome pathway and cellular responses to oxidative stress. Free Radical Biology and Medicine. 51(1):5-16.
Informing food choices and health outcomes by use of the dietary glycemic index - (Review Article)
Chiu, C., Liu, S., Willett, W., Wolever, T., Brand-Miller, J., Barclay, A., Taylor, A. 2011. Informing food choices and health outcomes by use of the dietary glycemic index. Nutrition Reviews. 69(4):231-242.
Dietary hyperglycemia, glycemic index and age-related metabolic retinal diseases - (Peer Reviewed Journal)
Chiu, C., Taylor, A. 2011. Dietary hyperglycemia, glycemic index and age-related metabolic retinal diseases. Progress in Retinal and Eye Research. 30(1):18-53.
A mirccroarray analysis of sexual dimorphism of adipose tissues in high-fat-diet-induced obese mice - (Peer Reviewed Journal)
Grove, K.L., Fried, S.K., Greenberg, A.S., Ziao, X.Q., Clegg, D.J. 2010. mirccroarray analysis of sexual dimorphism of adipose tissues in high-fat-diet-induced obese mice. International Journal of Obesity. 34(6):989-1000.
Ubiquitin proteasome pathway-mediated degradation of proteins: effects due to site-specific substrate deamidation - (Peer Reviewed Journal)
Dudek, E.J., Lampi, K.J., Lampi, J., Shang, F., King, J., Wang, Y., Taylor, A. 2010. Ubiquitin proteasome pathway-mediated degradation of proteins: effects due to site-specific substrate deamidation. Investigative Ophthalmology and Visual Science. 51(8):4164-4173.
Dietary carbohydrate in relation to cortical and nuclear lens opacities in the Melbourne Visual Impairment Project - (Peer Reviewed Journal)
Chiu, C.J., Robman, L., Mccarty, C.A., Mukesh, B.N., Taylor, H., Taylor, A. 2010. Dietary carbohydrate in relation to cortical and nuclear lens opacities in the Melbourne Visual Impairment Project. Investigative Ophthalmology and Visual Science. 51(6):2897-2905.
Last Modified: 9/22/2014
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