Location: Bovine Functional Genomics
2013 Annual Report
1)continued genomic re-sequencing of animals for the purposes of single nucleotide polymorphism (SNP) discovery, diversity characterization, and fine mapping of causative mutations,.
2)analysis of beadchip genotypic data for the continued refinement of genetic prediction equations within breed,.
3)collaborative development of the beadchips as enhanced-value genotyping platforms optimized for value and imputation, and.
4)identification of haplotypes affecting fertility in Holstein, Jersey, and Brown Swiss breeds of cattle. Through industry partnerships, over 500,000 animals to date were genotyped using a variety of platforms. These data are being used for the estimation of genomic breeding values in the dairy and beef industries. The rate of growth of data collection for genotypes continues to accelerate in both industries. The BovineLD assay and products derived from this platform were rapidly adopted in dairy cattle genetic evaluations. The vast majority of animals recently genotyped were done using a BovineLD or derived assay. This research supports two objectives of its related in-house project:.
1)to use genotypic data and the resulting bovine haplotype map to enhance genetic improvement in dairy cattle through development and implementation of whole genome selection and enhanced parentage verification approaches (Objective 2), and.
2)to characterize conserved genome elements and identify functional genetic variation (Objective 3).