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United States Department of Agriculture

Agricultural Research Service

Research Project: NUTRITION, OBESITY, CARDIOVASCULAR HEALTH AND GENOMICS

Location: Human Nutrition Research Center on Aging

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)

Clock 3111 T/c Snp Interacts with Emotional Eating Behavior for Weight-Loss in a Mediterranean Population - (Peer Reviewed Journal)
CLOCK 3111 T/C SNP interacts with emotional eating behavior for weight-loss in a Mediterranean population. PLoS One. 9(6):e99152.
Genome-wide association studies identified novel loci for non-high-density lipoprotein cholesterol and its postprandial lipemic response - (Peer Reviewed Journal)
An, P., Straka, R.J., Pollin, T.I., Feitosa, M.F., Wojczynski, M.K., Daw, E., O'Connell, J.R., Gibson, Q., Ryan, K.A., Hopkins, P.N., Tsai, M.Y., Lai, C., Province, M.A., Ordovas, J.M., Shuldiner, A.R., Arnett, D.K., Borecki, I.B. 2014. Genome-wide association studies identified novel loci for non-high-density lipoprotein cholesterol and its postprandial lipemic response. Human Genetics. DOI: 10.1007/s00439-014-1435-3.
Docosahexaenoic acid modulates the enterocyte Caco-2 cell expression of MicroRNAs involved in lipid metabolism - (Peer Reviewed Journal)
Gil-Zamorano, J., Martin, R., Daimiel, L., Richardson, K., Giordano, E., Nicod, N., García-Carrasco, B., Soares, S.A., Iglesias-Gutiérrez, E., Lasunción, M.A., Sala-Vila, A., Rose, E., Ordovas, J.M., Visioli, F., Davalos, A. 2014. Docosahexaenoic acid modulates the enterocyte Caco-2 cell expression of MicroRNAs involved in lipid metabolism. Journal of Nutrition. 144(5):575-585. DOI: 10.3945/JN.113.189050.
Lipoprotein(a) levels in familial hipercholesterolaemia: an important predictor for cardiovascular disease independent of the type of LDL-receptor mutation - (Peer Reviewed Journal)
Alonso, R., Andres, E., Mata, N., Fuentes-Jimenez, F., Badimon, L., Lopez-Miranda, J., Padro, T., Muniz, O., Diaz-Diaz, J., Mauri, M., Ordovas, J.M., Mata, P. 2014. Lipoprotein(a) levels in familial hipercholesterolaemia: an important predictor for cardiovascular disease independent of the type of LDL-receptor mutation. American Journal of Opthalmology. 63(19):1982-1989.
Cry1 Circadian Gene Variant Interacts with Carbohydrate Intake for Insulin Resistance in Two Independent Populations: Mediterranean and North American - (Peer Reviewed Journal)
Dashti, H.S., Smith, C.E., Lee, Y., Parnell, L.D., Lai, C., Arnett, D.K., Ordovas, J.M., Garaulet, M. 2014. CRY1 circadian gene variant interacts with carbohydrate intake for insulin resistance in two independent populations: Mediterranean and North American. Chronobiology International. 31(5):660-668. DOI: 10.3109/07420528.2014.886587.
Association of low-frequency and rare coding-sequence variants with blood lipids and Coronary Heart Disease in 56,000 whites and blacks - (Peer Reviewed Journal)
Peloso, G.M., Auer, P.L., Bis, J.C., Voorman, A., Morrison, A.C., Stitziel, N.O., Brody, J.A., Khetarpal, S.A., Crosby, J.R., Fornage, M., Isaacs, A., Jakobsdottir, J., Feitosa, M.F., Davies, G., Huffman, J.E., Manichaikul, A., Davis, B., Lohman, K., Joon, A.Y., Smith, A.V., Grove, M.L., Zanoni, P., Redon, V., Demissie, S., Lawson, K., Peters, U., Carlson, C., Jackson, R.D., Ryckman, K.K., Mackey, R.H., Robinson, J.G., Siscovick, D.S., Schreiner, P.J., Mychaleckyj, J.C., Pankow, J.S., Hofman, A., Uitterlinden, A.G., Harris, T.B., Taylor, K.D., Stafford, J.M., Reynolds, L.M., Marioni, R.E., Dehghan, A., Franco, O.H., Patel, A.P., Lu, Y., Hindy, G., Gottesman, O., Bottinger, E.P., Melander, O., Orho-Melander, M., Loos, R., Duga, S., Merlini, P., Farrall, M., Goel, A., Asselta, R., Girelli, D., Martinelli, N., Shah, S.H., Kraus, W.E., Li, M., Rader, D.J., Reilly, M.P., Mcpherson, R., Watkins, H., Ardissino, D., Zhang, Q., Wang, J., Tsai, M.Y., Taylor, H.A., Correa, A., Griswold, M.E., Lange, L.A., Starr, J.M., Rudan, I., Eiriksdottir, G., Launer, L.J., Ordovas, J.M., Levy, D., Chen, Y., Reiner, A.P., Hayward, C., Polasek, O., Deary, I.J., Borecki, I.B., Liu, Y., Gudnason, V., Wilson, J., Van Duijn, C.M., Kooperberg, C., Rich, S.S. 2014. Association of low-frequency and rare coding-sequence variants with blood lipids and Coronary Heart Disease in 56,000 whites and blacks. The American Journal of Human Genetics. 94:223-232.
Amino Acid Change in the Carbohydrate Response Element Binding Protein is associated with lower triglycerides and myocardial infarction incidence depending on level of adherence to the Mediterranean diet in the PREDIMED trial - (Peer Reviewed Journal)
Ortega-Azorín, C., Sorlí, J.V., Estruch, R., Asensio, E.M., Coltell, O., Gonzalez, J.I., Martinez-Gonzalez, M., Ros, E., Salas-Salvado, J., Fito, M., Aros, F., Lapetra, J., Serra-Majem, L., Ruiz-Gutierrez, V., Gomez-Garcia, E., Fiol, M., Flores, G., Pinto, X., Saiz, C., Ordovas, J.M., Corella, D. 2014. Amino Acid Change in the Carbohydrate Response Element Binding Protein is associated with lower triglycerides and myocardial infarction incidence depending on level of adherence to the Mediterranean diet in the PREDIMED trial. Circulation: Cardiovascular Genetics. 7(1):49-58. DOI:10.1161/CIRCGENETICS.113.000301.
Novel association of the obesity risk-allele near Fas Apoptotic Inhibitory molecule 2 (FAIM2) gene with heart rate and study of its effects on myocardial infarction in diabetic participants of the PREDIMED trial - (Peer Reviewed Journal)
Corella, D., Sorli, J.V., Gonzalez, J.I., Ortega, C., Fito, M., Bullo, M., Martinez-Gonzalez, M., Ros, E., Aros, F., Lapetra, J., Gomez-Gracia, E., Serra-Majem, L., Ruiz-Gutierrez, V., Fiol, M., Coltell, O., Vinyoles, E., Pinto, X., Marti, A., Saiz, C., Ordovas, J.M., Estruch, R. 2014. Novel association of the obesity risk-allele near Fas Apoptotic Inhibitory molecule 2 (FAIM2) gene with heart rate and study of its effects on myocardial infarction in diabetic participants of the PREDIMED trial. Cardiovascular Diabetology. 5:1-13.
Additive influence of genetic predisposition and conventional risk factors in the incidence of coronary heart disease: a population-based study in Greece - (Peer Reviewed Journal)
Yiannakouris, N., Katsoulis, M., Trichopoulou, A., Ordovas, J.M., Trichopoulos, D. 2014. Additive influence of genetic predisposition and conventional risk factors in the incidence of coronary heart disease: a population-based study in Greece. BMJ Open. DOI: 10.1136/bmjopen-2013-004387.
Beneficial effect of CLOCK gene polymorphism rs1801260 in combination with low-fat diet on insulin metabolism in the patients with metabolic syndrome - (Peer Reviewed Journal)
Garcia-Rios, A., Gomez-Delgado, F., Garaulet, M., Alcala-Diaz, J., Delgado-Lista, F., Marin, C., Ranguel-Zuniga, O., Rodriguez-Cantalejo, F., Gomez-Luna, P., Ordovas, J.M., Perez-Jimenez, F., Lopez-Miranda, J., Perez-Martinez, P. 2014. Beneficial effect of CLOCK gene polymorphism rs1801260 in combination with low-fat diet on insulin metabolism in the patients with metabolic syndrome. Chronobiology International. 31(3):401-408.
Circadian rhythmicity as a predictor of weight-loss effectiveness - (Peer Reviewed Journal)
Bandín, C., Martinez-Nicolas, A., Ordovas, J.M., Madrid, J.A., Garaulet, M. 2013. Circadian rhythmicity as a predictor of weight-loss effectiveness. International Journal of Obesity. DOI: 10.1038/ijo.2013.211.
Epigenome-wide association study of fasting measures of glucose, insulin, and HOMA-IR in the genetics of lipid lowering drugs and diet network study - (Peer Reviewed Journal)
Hidalgo, B., Irvin, I.M., Sha, J., Zhi, D., Aslibekyan, S., Absher, D., Tiwari, H.K., Kabagambe, E.K., Ordovas, J.M., Arnett, D.K. 2014. Epigenome-wide association study of fasting measures of glucose, insulin, and HOMA-IR in the genetics of lipid lowering drugs and diet Network Study. Diabetes. 63(2):801-807.
Sedentary lifestyle and its relation to cardiovascular risk factors, insulin resistance and inflammatory profile - (Peer Reviewed Journal)
Leon-Latre, M., Moreno-Franco, B., Andres-Esteban, E.M., Ledesma, M., Laclaustra, M., Alcalde, V., Penalvo, J.L., Ordovas, J.M., Casasnovas, J.A. 2014. Sedentary lifestyle and its relation to cardiovascular risk factors, insulin resistance and inflammatory profile. Revista Espanola De Cardiologia. 67(6):449-455.
Apolipoprotein A2 polymorphism interacts with intakes of dairy foods to influence body weight in 2 U.S. populations - (Peer Reviewed Journal)
Smith, C.E., Tucker, K.L., Arnett, D.K., Noel, S.E., Corella, D., Borecki, I.B., Feitosa, M.F., Aslibekyan, S., Parnell, L.D., Lai, C., Lee, Y., Ordovas, J.M. 2013. Apolipoprotein A2 polymorphism interacts with intakes of dairy foods to influence body weight in 2 U.S. populations. Journal of Nutrition. 143(12):1865-1871.
Common variants associated with plasma triglycerides and risk for coronary artery disease - (Peer Reviewed Journal)
Do, R., Willer, C.J., Schmidt, E.M., Sengupta, S., Gao, C., Peloso, G.M., Gustafsson, S., Kanoni, S., Ganna, A., Chen, J., Buchkovich, M.L., Mora, S., Beckmann, J.S., Bragg-Gresham, J.L., Chang, H., Demirkan, A., Den Hertog, H.M., Donnelly, L.A., Ehret, G.B., Esko, T., Feitosa, M.F., Ferreira, T., Fischer, K., Fontanillas, P., Fraser, R.M., Freitag, D.F., Gurdasani, D., Heikkilä, K., Hyppönen, E., Isaacs, A. 2013. Common variants associated with plasma triglycerides and risk for coronary artery disease. Nature Genetics. 45(11):1345-1352. DOI: 10.1038/NG.2795.
Rev-Erb-Alpha Circadian Gene Variant Associates with Obesity in Two Independent Populations: Mediterranean and North American - (Peer Reviewed Journal)
Garaulet, M., Smith, C.E., Gomez-Abellan, P., Ordova S-Montanes, M., Lee, Y., Parnell, L.D., Arnett, D.K., Ordovas, J.M. 2014. REV-ERB-ALPHA circadian gene variant associates with obesity in two independent populations: Mediterranean and North American. Molecular Nutrition and Food Research. 58(4):821-829.
Can genotype be used to tailor treatment of obesity? State of the art and guidelines for future studies and applications - (Review Article)
Corella, D., Ordovas, J.M. 2013. Can genotype be used to tailor treatment of obesity? State of the art and guidelines for future studies and applications. Minerva Endocrinologica. 38(3):219-235.
SNPs located at CpG sites modulate genome-epigenome interaction - (Peer Reviewed Journal)
Zhi, D., Aslibekyan, S., Irvin, M., Claas, S.A., Borecki, I.B., Ordovas, J.M., Absher, D.M., Arnett, D.K. 2013. SNPs located at CpG sites modulate genome-epigenome interaction. Epigenetics. 8(8):802-806.
Mediterranean diet reduces the adverse effect of the TCF7L2-rs7903146 polymorphism on cardiovascular risk factors and stroke incidence: a randomized controlled trial in a high-cardiovascular-risk population - (Peer Reviewed Journal)
Corella, D., Carrasco, P., Sorlí, J.V., Estruch, R., Rico-Sanz, J., Martinez-Gonzalez, M., Salas-Salvado, J., Covas, M., Coltell, O., Aros, F., Lapetra, J., Serra-Majem, L., Ruiz-Gutierrez, V., Warnberg, J., Fiol, M., Pinto, X., Ortega-Azorin, C., Munoz, A., Martinez, J., Gomez-Garcia, E., Gonzalez, J.I., Ros, E., Ordovas, J.M. 2013. Mediterranean diet reduces the adverse effect of the TCF7L2-rs7903146 polymorphism on cardiovascular risk factors and stroke incidence: a randomized controlled trial in a high-cardiovascular-risk population. Diabetes Care. 36:3803-3811.
Quantifying diet for nutrigenomic studies - (Review Article)
Tucker, K.L., Smith, C.E., Lai, C., Ordovas, J.M. 2013. Quantifying diet for nutrigenomic studies. Annual Review of Nutrition. 33:349-371.
Effects of polymorphisms in vitamin E-, vitamin C-, and glutathione peroxidase-related genes on serum biomarkers and associations with glaucoma - (Peer Reviewed Journal)
Zanon-Moreno, V., Asensio-Marquez, E.M., Ciancotti-Oliver, L., Garcia-Medina, J.J., Sanz, P., Ortega-Azorin, C., Pinazo-Duran, M.D., Ordovas, J.M., Corella, D. 2013. Effects of polymorphisms in vitamin E-, vitamin C-, and glutathione peroxidase-related genes on serum biomarkers and associations with glaucoma. Molecular Vision. 19:231-242.
The association between LRP-1 variants and chylomicron uptake after a high fat meal - (Peer Reviewed Journal)
Frazier-Wood, A.C., Kabagambe, E.K., Wojczynski, M.K., Borecki, I.B., Tiwari, H.K., Smith, C.E., Ordovas, J.M., Arnett, D.K. 2013. The association between LRP-1 variants and chylomicron uptake after a high fat meal. Nutrition, Metabolism and Cardiovascular Diseases. DOI: 10.1016/j.numecd.2012.12.007.
Timing of food intake predicts weight loss effectiveness - (Peer Reviewed Journal)
Garaulet, M., Gomez-Abellan, P., Alburquerque-Bejar, J.J., Lee, Y., Ordovas, J.M., Scheer, F.A. 2013. Timing of food intake predicts weight loss effectiveness. International Journal of Obesity. 37:604-611.
Curcumin and aging - (Review Article)
Shen, L., Parnell, L.D., Ordovas, J., Lai, C. 2013. Curcumin and aging. Biofactors. 39(1):133-140.
Genetic variants at PSMD3 interact with dietary fat and carbohydrate to modulate insulin resistance - (Peer Reviewed Journal)
Zheng, J., Arnett, D., Parnell, L.D., Lee, Y., Ma, Y., Smith, C., Richardson, K., Li, D., Ordovas, J., Tucker, K., Lai, C., Borecki, I. 2013. Genetic variants at PSMD3 interact with dietary fat and carbohydrate to modulate insulin resistance. Journal of Nutrition. 143(3):354-361.
Genetic variants associated with VLDL, LDL and HDL particle size differ with race/ethnicity - (Peer Reviewed Journal)
Frazier-Wood, A.C., Manichaikul, A., Aslibekyan, S., Borecki, I.B., Goff, D.C., Hopkins, P.N., Lai, C., Ordovas, J.M., Post, W.S., Rich, S.S., Sale, M.M., Siscovick, D., Straka, R.J., Tiwari, H.K., Tsai, M.Y., Rotter, J.I., Arnett, D.K. 2013. Genetic variants associated with VLDL, LDL and HDL particle size differ with race/ethnicity. Human Genetics. 132(4):405-413.
Lipoprotein receptor-related protein 1 variants and dietary fatty acids: meta-analysis of European origin and African American studies - (Peer Reviewed Journal)
Smith, C.E., Ngwa, J., Tanaka, T., Qi, Q., Wojczynski, M.K., Lemaitre, R.N., Anderson, J.S., Manichaikul, A., Mikkila, V., Van Rooij, F.J., Ye, Z., Bandinelli, S., Frazier-Wood, A.C., Houston, D.K., Hu, F., Langenberg, C., Mckeown, N.M., Mozaffarian, D., North, K.E., Viikari, J., Zillikens, M.C., Djousse, L., Hofman, A., Kahonen, M., Kabagambe, E.K., Loos, R.J., Saylor, G.B., Forouhi, N.G., Liu, Y., Mukamal, K.J., Chen, Y.I., Tsai, M.Y., Uitterlinden, A.G., Raitakari, O., Van Duijn, C.M., Arnett, D.K., Borecki, I.B., Cupples, L., Ferrucci, L., Kritchevsky, S.B., Lehtimaki, T., Qi, L., Rotter, J.I., Siscovick, D.S., Wareham, N.J., Witteman, J.C., Ordovas, J.M., Nettleton, J.A. 2013. Lipoprotein receptor-related protein 1 variants and dietary fatty acids: meta-analysis of European origin and African American studies. International Journal of Obesity. DOI: 10.1038/ijo.2012.215.
Association between BDNF-rs6265 and obesity in the Boston Puerto Rican Health Study - (Peer Reviewed Journal)
Ma, X., Qiu, W., Smith, C., Parnell, L.D., Jiang, Z., Ordovas, J., Tucker, K., Lai, C. 2012. Association between BDNF-rs6265 and obesity in the Boston Puerto Rican Health Study. Journal of Obesity. DOI: 10.1155/2012102942.
Carbohydrate nutrition differs by diabetes status and is associated with dyslipidemia in Boston Puerto Rican adults without diabetes - (Peer Reviewed Journal)
Van Rompay, M.I., Mckeown, N.M., Castaneda-Sceppa, C., Ordovas, J.M., Tucker, K.L. 2013. Carbohydrate nutrition differs by diabetes status and is associated with dyslipidemia in Boston Puerto Rican adults without diabetes. Journal of Nutrition. 143(2):182-199.
Statistical and biological gene-lifestyle interactions of MC4R and FTO with diet and physical activity on obesity: new effects on alcohol consumption - (Peer Reviewed Journal)
Corella, D., Ortega-Azorin, C., Sorli, J.V., Covas, M., Carrasco, P., Salas-Salvado, J., Martinez-Gonzalez, M., Aros, F., Lapetra, J., Serra-Majem, L., Lamuela-Raventos, R., Gomez-Gracia, E., Fiol, M., Pinto, X., Ros, E., Marti, A., Coltell, O., Ordovas, J.M., Estruch, R. 2012. Statistical and biological gene-lifestyle interactions of MC4R and FTO with diet and physical activity on obesity: new effects on alcohol consumption. PLoS One. 7(12):e52344.
Genetic analysis of 16 NMR-lipoprotein fractions in humans, the GOLDN study - (Peer Reviewed Journal)
Kraja, A.T., Borecki, I.B., Tsai, M.Y., Ordovas, J.M., Hopkins, P.N., Lai, C., Frazier-Wood, A.C., Straka, R.J., Hixson, J.E., Province, M.A. 2013. Genetic analysis of 16 NMR-lipoprotein fractions in humans, the GOLDN study. Lipids. 48(2):155-165.
Glucocorticoids affect 24 h clock genes expression in human adipose tissue explant cultures - (Peer Reviewed Journal)
Gomez-Abellan, P., Diez-Noguera, A., Madrid, J.A., Lujan, J.A., Ordovas, J.M., Garaulet, M. 2012. Glucocorticoids affect 24 h clock genes expression in human adipose tissue explant cultures. PLoS One. DOI: 10.1371/journal.pone.0050435.
Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations - (Peer Reviewed Journal)
Elbers, C.C., Guo, Y., Tragante, V., Van Iperen, E.P., Lanktree, M.B., Castillo, B., Chen, F., Yanek, L.R., Wojczynski, M.K., Li, Y.R., Ferwerda, B., Ballantyne, C.M., Buxbaum, S.G., Chen, Y.I., Chen, W., Cupples, L., Cushman, M., Duan, Y., Duggan, D., Evans, M.K., Fernandes, J., Fornage, M., Garcia, M., Garvey, W.T., Glazer, N., Gomez, F., Harris, T.B., Halder, I., However, V.J., Keller, M., Kamboh, M.I., Kooperberg, C., Kritchevsky, S.B., Lacroix, A., Liu, K., Liu, Y., Musunuru, K., Newman, A.B., Onland-Moret, C.N., Ordovas, J.M., Peter, I., Post, W., Redline, S., Reis, S.E., Saxena, R., Schreiner, P.J., Volcik, K.A., Wang, X., Yusuf, S., Zonderland, A.B., Anand, S.S., Becker, D.M., Psaty, B., Rader, D.J., Reiner, A.P., Rich, S.S., Rotter, J.I., Sale, M.M., Tsai, M.Y., Borecki, I.B., Hegele, R.A., Kathiresan, S., Nalls, M.A., Taylor, H.A., Hakonarson, H., Sivapalaratnam, S., Asselbergs, F.W., Drenos, F., Wilson, J.G., Keating, B.J. 2012. Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations. PLoS One. DOI: 10.1371/journal.pone.0050198.
Differences in circadian rhythmicity in CLOCK 3111T/C genetic variants in moderate obese women as assessed by thermometry, actimetry and body position     Reprint Icon - (Peer Reviewed Journal)
Bandin, C., Martinez-Nicolas1ano, A., Ordovas, J.M., Ros, L.J., Castell, P., Silvente, T., Madrid, J., Garaulet, M. 2013. Differences in circadian rhythmicity in CLOCK 3111T/C genetic variants in moderate obese women as assessed by thermometry, actimetry and body position. International Journal of Obesity. 37(8):1044-1050.
Variants identified in a GWAS meta-analysis for blood lipids are associated with the lipid response to fenofibrate - (Peer Reviewed Journal)
Aslibekyan, S., Goodarzi, M.O., Frazier-Wood, A.C., Yan, X., Irvin, M.R., Kim, E., Tiwari, H.K., Guo, X., Straka, R.J., Taylor, K.D., Tsai, M.Y., Hopkins, P.N., Korenman, S.G., Borecki, I.B., Chen, Y.I., Ordovas, J.M., Rotter, J.I., Arnett, D.K. 2012. Variants identified in a GWAS meta-analysis for blood lipids are associated with the lipid response to fenofibrate. PLoS One. 7(10):e48663.
Mechanism of action of recombinant Acc-royalisin from royal jelly of Chinese honeybee against gram-positive bacteria - (Peer Reviewed Journal)
Shen, L., Liu, D., Yang, X., Jin, F., Din, M., Parnell, L.D., Lai, C. 2012. Mechanism of action of recombinant Acc-royalisin from royal jelly of Chinese honeybee against gram-positive bacteria. PLoS One. 7(10):e47194 DOI: 10.1371/journal.pone.0047194.
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci - (Peer Reviewed Journal)
Asselbergs, F.W., Guo, Y., Van Iperen, E.P., Sivapalaratnam, S., Tragante, V., Lanktree, M.B., Lange, L.A., Almoguera, B., Appelman, Y.E., Barnard, J., Baumert, J., Beitelshees, A.L., Bhangale, T.R., Chen, Y., Gaunt, T.R., Gong, Y., Hopewell, J.C., Johnson, T., Kleber, M.E., Langaee, T.Y., Li, M., Li, Y.R., Liu, K., Mcdonough, C.W., Meijs, M.F., Middelberg, R.P., Musunuru, K., Nelson, C.P., O'Connell, J.R., Padmanabhan, S., Pankow, J.S., Pankratz, N., Rafelt, S., Rajagopalan, R., Romaine, S.P., Schork, N.J., Shaffer, J., Shen, H., Smin, E.N., Tischfield, S.E., Van Der Most, P.J., Vanvliet-Ostaptchouk, J.V., Verweij, N., Volcik, K.A., Zhang, L., Bailey, K.R., Bailey, K.M., Bauer, F., Boer, J.M., Braund, P.S., Burt, A., Burton, P.R., Buxbaum, S.G., Chen, W., Cooper-Dehoff, R.M., Cupples, L., Dejong, J.S., Delles, C., Duggan, D., Fornage, M., Furlong, C.E., Glazer, N., Gums, J.G., Hastie, C., Holmes, M.V., Illig, T., Kirkland, S.A., Kivimaki, M., Klein, R., Klein, B.E., Kooperberg, C., Kottke-Marchant, K., Kumari, M., Lacroix, A.Z., Mallela, L., Murugesan, G., Ordovas, J., Ouwehand, W.H., Post, W.S., Saxena, R., Scharnagl, H., Schreiner, P.J., Shah, T., Shields, D.C., ... Drenos, F. 2012. Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. American Society of Human Genetics. 91(5):823-838.
Genome-wide association study indicates variants associated with insulin signaling and inflammation mediate lipoprotein responses to fenofibrate - (Peer Reviewed Journal)
Frazier-Wood, A.C., Aslibekyan, S., Borecki, I.B., Hopkins, P.N., Lai, C., Ordovas, J.M., Straka, R.J., Tiwari, H.K., Arnett, D.K. 2012. Genome-wide association study indicates variants associated with insulin signaling and inflammation mediate lipoprotein responses to fenofibrate. Pharmacogenetics and Genomics. 22(10):750-757.
Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network - (Peer Reviewed Journal)
Aslibekyan, S., An, P., Frazier-Wood, A.C., Kabagambe, E.K., Irvin, M.R., Straka, R.J., Tiwari, H.K., Tsa, M.Y., Hopkins, P.N., Borecki, I.B., Ordovas, J.M., Arnett, D.K. 2012. Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network. Nutrition, Metabolism and Cardiovascular Diseases. DOI: 10.1016/j.numecd.2012.07.010.
Low density lipoprotein receptor related protein 1 variant interacts with saturated fatty acids in Puerto Ricans - (Peer Reviewed Journal)
Smith, C.E., Tucker, K.L., Lee, Y., Lai, C., Parnell, L.D., Ordovas, J.M. 2013. Low density lipoprotein receptor related protein 1 variant interacts with saturated fatty acids in Puerto Ricans. Obesity. 21:602-608.
Aragon workers' health study - design and cohort description - (Peer Reviewed Journal)
Casasnovas, J.A., Alcalde, V., Civeira, F., Guallar, E., Ibanez, B., Jimenez-Borreguero, J., Laclaustra, M., Leon, M., Ordovas, J.M., Pocovi, M., Sanz, G., Fuster, V. 2012. Aragon workers' health study - design and cohort description. BioMed Central - Cardiovascular Disorders. 12(1):45.
Curcumin-supplemented diets increase superoxide dismutase activity and mean lifespan in Drosophila - (Peer Reviewed Journal)
Shen, L., Xiao, F., Peng, Y., Chen, Y., Qi-Kang, G., Parnell, L.D., Meydani, M., Ordovas, J.M., Li, D., Lai, C. 2013. Curcumin-supplemented diets increase superoxide dismutase activity and mean lifespan in Drosophila. Journal of the American Aging Association (AGE). 35(4):1133-1142. DOI 10.1007/s11357-012-9438-2.
Assessment of the value of a genetic risk score in improving the estimation of coronary risk - (Peer Reviewed Journal)
Lluis-Ganella, C., Subirana, I., Lucas, G., Tomas, M., Munoz, D., Senti, M., Salas, E., Sala, J., Ramos, R., Ordovas, J.M., Marrugat, J., Elosua, R. 2012. Assessment of the value of a genetic risk score in improving the estimation of coronary risk. Atherosclerosis. 222(2):456-463.
Report of the National Heart, Lung, and Blood Institute Working Group on epigenetics and hypertension - (Review Article)
Cowley, A.W., Nadeau, J.H., Baccarelli, A., Berecek, K., Fornage, M., Gibbons, G.H., Harrison, D.G., Liang, M., Nathanielsz, P.W., O'Connor, D.T., Ordovas, J.M., Peng, W., Soares, M., Szyf, M., Tolunay, H.E., Wood, K.C., Zhao, K., Galis, Z.S. 2012. Report of the National Heart, Lung, and Blood Institute Working Group on epigenetics and hypertension. Hypertension. 59(5):899-905.
Genetic predisposition to coronary heart disease and stroke using an additive genetic risk score: a population-based study in Greece - (Peer Reviewed Journal)
Yiannakouris, N., Katsoulis, M., Dilis, V., Parnell, L.D., Trichopoulos, D., Ordovas, J., Trichopoulou, A. 2012. Genetic predisposition to coronary heart disease and stroke using an additive genetic risk score: a population-based study in Greece. Atherosclerosis. 222(1):175-179.
The PPAR alpha gene is associated with triglyceride, low-density cholesterol and inflammation marker response to fenofibrate intervention: the GOLDN study - (Peer Reviewed Journal)
Frazier-Wood, A.C., Ordovas, J.M., Straka, R.J., Hixson, J.E., Borecki, I.B., Tiwari, H.K., Arnett, D.K. 2012. The PPAR alpha gene is associated with triglyceride, low-density cholesterol and inflammation marker response to fenofibrate intervention: the GOLDN study. The Pharmacogenomics Journal. DOI: 10.1038/TPJ.2012.9.
Genetic variation in fatty acid elongases is not associated with intermediate cardiovascular phenotypes or myocardial infarction - (Peer Reviewed Journal)
Aslibekyan, S., Jensen, M.K., Campos, H., Linkletter, C.D., Loucks, E.B., Ordovas, J.M., Deka, R., Rimm, E.B., Baylin, A. 2012. Genetic variation in fatty acid elongases is not associated with intermediate cardiovascular phenotypes or myocardial infarction. European Journal of Clinical Nutrition. 66(3):353-359.
Interactions between dietary n-3 fatty acids and genetic variants and risk of disease - (Review Article)
Corella, D., Ordovas, J. 2012. Interactions between dietary n-3 fatty acids and genetic variants and risk of disease. British Journal of Nutrition. 107:S271-S283.
Preliminary evidence for an association between LRP-1 genotype and body mass index in humans - (Peer Reviewed Journal)
Frazier-Wood, A.C., Kabagambe, E.K., Borecki, I.B., Tiwari, H.K., Ordovas, J.M., Arnett, D.K. 2012. Preliminary evidence for an association between LRP-1 genotype and body mass index in humans. PLoS One. 7(2):e30732.
A clustering analysis of lipoprotein diameters in the metabolic syndrome - (Peer Reviewed Journal)
Frazier-Wood, A.C., Glasser, S., Garvey, W.T., Kabagambe, E.K., Borecki, I.B., Tiwari, H.K., Tsai, M.Y., Hopkins, P.N., Ordovas, J.M., Arnett, D.K. 2011. A clustering analysis of lipoprotein diameters in the metabolic syndrome. Lipids in Health and Disease. 10:237.
Adaptive genetic variation and population differences - (Book / Chapter)
Lai, C. 2012. Adaptive genetic variation and population differences. In: Bouchard, C., Ordovas, J. M., editors. Recent Advances in Nutrigenetics and Nutrigenomics. Oxford, UK: Elsevier. 108:461-489. PMID.22656388.
A polymorphism in a gene encoding Perilipin 4 is associated with height but not with bone measures in individuals from the Framingham Osteoporosis Study - (Peer Reviewed Journal)
Cusano, N., Kiel, D., Demissie, S., Karasik, D., Cupples, L., Corella, D., Gao, Q., Richardson, K., Yiannakouris, N., Ordovas, J. 2012. A polymorphism in a gene encoding Perilipin 4 is associated with height but not with bone measures in individuals from the Framingham Osteoporosis Study. Calcified Tissue International. 90(2):96-197.
A powerful test of parent-of-origin effects for quantitative traits using haplotypes - (Peer Reviewed Journal)
Feng, R., Wu, Y., Jang, G., Ordovas, J.M., Arnett, D.K. 2011. A powerful test of parent-of-origin effects for quantitative traits using haplotypes. PLoS One. 6(12):e28909.
Sirt1 and Clock 3111t Greater Than C Combined Genotype Is Associated with Evening Preference and Weight Loss Resistance in a Behavioral Therapy Treatment for Obesity - (Peer Reviewed Journal)
Garaulet, M., Esteban Tardido, A., Lee, Y., Smith, C., Parnell, L.D., Ordovas, J. 2012. SIRT1 and CLOCK 3111T greater than C combined genotype is associated with evening preference and weight loss resistance in a behavioral therapy treatment for obesity. International Journal of Obesity. DOI: 10.1038/ijo.2011.270.
Fatty acid desaturase gene variants, cardiovascular risk factors, and myocardial infarction in the costa rica study - (Peer Reviewed Journal)
Aslibekyan, S., Jensen, M.K., Campos, H., Linkletter, C.D., Loucks, E.B., Ordovas, J.M., Deka, R., Rimm, E.B., Baylin, A. 2012. Fatty acid desaturase gene variants, cardiovascular risk factors, and myocardial infarction in the costa rica study. Frontiers in Genetics. 3:72.
The effect of CYP7A1 polymorphisms on lipid responses to fenofibrate - (Peer Reviewed Journal)
Shen, J., Arnett, D., Parnell, L.D., Lai, C., Straka, R., Hopkins, P., An, P., Feitosa, M., Ordovas, J. 2012. The effect of CYP7A1 polymorphisms on lipid responses to fenofibrate. Journal of Cardiovascular Pharmacology. 59(3):254-259.
High-fat meal effect on LDL, HDL, and VLDL particle size and number in the Genetics of Lipid-Lowering Drugs and Diet Network (GOLDN): an interventional study - (Peer Reviewed Journal)
Wojczynski, M.K., Glasser, S.P., Oberman, A., Kabagambe, E.K., Hopkins, P.N., Tsai, M.Y., Straka, R.J., Ordovas, J.M., Arnett, D.K. 2011. High-fat meal effect on LDL, HDL, and VLDL particle size and number in the Genetics of Lipid-Lowering Drugs and Diet Network (GOLDN): an interventional study. Lipids in Health and Disease. 10:181.
A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS - (Peer Reviewed Journal)
Richardson, K., Lai, C., Parnell, L.D., Lee, Y., Ordovas, J. 2011. A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS. Biomed Central (BMC) Genomics. 2:504.
A high intake of saturated fatty acids strengthens the association between the fat mass and obesity-associated gene and BMI - (Peer Reviewed Journal)
Corella, D., Arnett, D.K., Tucker, K.L., Kabagambe, E.K., Tsai, M.Y., Parnell, L.D., Lai, C., Lee, Y., Warodomwichit, D., Hopkins, P.N., Ordovas, J.M. 2011. A high intake of saturated fatty acids strengthens the association between the fat mass and obesity-associated gene and BMI. Journal of Nutrition. 141(12):2219-2225.
Update on perilipin polymorphisms and obesity - (Review Article)
Smith, C.E., Ordovas, J.M. 2012. Update on perilipin polymorphisms and obesity. Nutrition Reviews. 70(10):611-621.
A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network - (Peer Reviewed Journal)
Aslibekyan, S., Kabagambe, E.K., Irvin, M.R., Straka, R.J., Borecki, I.B., Tiwari, H.K., Tsai, M.Y., Hopkins, P.N., Shen, J., Lai, C., Ordovas, J.M., Arnett, D.K. 2012. A genome-wide association study of inflammatory biomarker changes in response to fenofibrate treatment in the Genetics of Lipid Lowering Drug and Diet Network. Pharmacogenetics and Genomics. 22(3):191-197.
Acculturation and sociocultural influences on dietary intake and health status among Puerto Rican adults in Massachusetts - (Peer Reviewed Journal)
Van Rompay, M., Mckeown, N., Casteneda-Sceppa, C., Falcon, L., Ordovas, J., Tucker, K. 2012. Acculturation and sociocultural influences on dietary intake and health status among Puerto Rican adults in Massachusetts. Journal of the Academy of Nutrition and Dietetics. 112(1):64-74.
Influence of menopause on adipose tissue clock gene genotype and its relationship with metabolic syndrome in morbidly obese women - (Peer Reviewed Journal)
Hernandez-Morante, J.J., Gomez-Santos, C., Margareto, J., Formiguera, X., Martinez-Carlos, M., Gonzalez, R., Martinez-Augustin, O., Madrid, J.A., Ordovas, J.M., Garaulet, M. 2011. Influence of menopause on adipose tissue clock gene genotype and its relationship with metabolic syndrome in morbidly obese women. Age. DOI 10.1007/s11357-011-9309-2.
Lipoprotein lipase S447X variant associated with VLDL, LDL and HDL diameter clustering in the MetS - (Peer Reviewed Journal)
Frazier-Wood, A.C., Glasser, S.P., Garvey, W.T., Kabagambe, E.K., Borecki, I.B., Tiwari, H.K., Tsai, M.Y., Hopkins, P.N., Ordovas, J.M., Arnett, D.K. 2011. Lipoprotein lipase S447X variant associated with VLDL, LDL and HDL diameter clustering in the MetS. Lipids in Health and Disease. 10:143.
Apolipoprotein A1/C3/A5 haplotypes and serum lipid levels - (Peer Reviewed Journal)
Yin, R., Li, Y., Lai, C. 2011. Apolipoprotein A1/C3/A5 haplotypes and serum lipid levels. Lipids in Health and Disease. 10:140. DOI: 10.1186/1476-511X-10-140.
Chronobiological aspects of obesity and metabolic syndrome - (Review Article)
Gomez-Abellan, P., Madrid, J., Ordovas, J.M., Garaulet, M. 2012. Chronobiological aspects of obesity and metabolic syndrome. Endocrinology and Nutrition. 59(1):50-61.
Cholesterol, inflammasomes, and atherogenesis - (Review Article)
Ordovas-Montanes, J., Ordovas, J. 2012. Cholesterol, inflammasomes, and atherogenesis. Current Cardiovascular Risk Reports. 6(1):45-52.
Clinical characteristics and evaluation of LDL-cholesterol treatment of the Spanish Familial Hypercholesterolemia Longitudinal Cohort Study (SAFEHEART) - (Peer Reviewed Journal)
Mata, N., Alonso, R., Badimon, L., Padro, T., Fuentes, F., Muniz, O., Perez-Jimenez, F., Lopez-Miranda, J., Diaz, J.L., Vidal, J.I., Barba, A., Piedecausa, M., Sanchez, J.F., Irigoyen, L., Guallar, E., Ordovas, J.M., Mata, P. 2011. Clinical characteristics and evaluation of LDL-cholesterol treatment of the Spanish Familial Hypercholesterolemia Longitudinal Cohort Study (SAFEHEART). Lipids in Health and Disease. DOI: 10.1186/1476-511X-10-94.
Site-specific circadian expression of leptin and its receptor in human adipose tissue - (Peer Reviewed Journal)
Gomez-Abellan, P., Gomez-Santos, C., Madrid, J.A., Milagro, F.I., Campion, J., Martinez, J.A., Lujan, J.A., Ordovas, J.M., Garaulet, M. 2011. Site-specific circadian expression of leptin and its receptor in human adipose tissue. Nutricion Hospitalaria. 26(6):1394-1401.
Evaluation of new and established age-related macular degeneration susceptibility genes in the Women's Health Initiative Sight Exam (WHI-SE) Study - (Peer Reviewed Journal)
Peter, I., Huggins, G.S., Ordovas, J.M., Haan, M., Seddon, J.M. 2011. Evaluation of new and established age-related macular degeneration susceptibility genes in the Women's Health Initiative Sight Exam (WHI-SE) Study. Journal of Ophthalmology. 152(6):1005-1013.
Fundamentals of nutrigenetics and nutrigenomics - (Book / Chapter)
Bouchard, C., Ordovas, J.M. 2012. Fundamentals of nutrigenetics and nutrigenomics. Progress in Molecular Biology and Translational Science. 108:1-15.
Sexual dimorphism in clock genes expression in human adipose tissue - (Peer Reviewed Journal)
Gomez-Abellan, P., Madrid, J.A., Lujan, J.A., Frutos, M.D., Gonzalez, R., Martinez-Augustin, O., Sanchez De Medina, F., Ordovas, J.M., Gauralet, M. 2012. Sexual dimorphism in clock genes expression in human adipose tissue. Obesity Surgery. 22(1):105-112.
Epigenetics lights up the obesity field - (Review Article)
Marti, A., Ordovas, J. 2011. Epigenetics lights up the obesity field. Obesity Facts: The European Journal of Obesity. 4(3):187-190.
Development of a cardiovascular risk score for use in low- and middle-income countries - (Peer Reviewed Journal)
Aslibekyan, S., Campos, H., Loucks, E.B., Linkletter, C.D., Ordovas, J.M., Baylin, A. 2011. Development of a cardiovascular risk score for use in low- and middle-income countries. Journal of Nutrition. 141(7):1375-1380.
Effects of APOA5 S19W polymorphism on growth, insulin sensitivity and lipoproteins in normoweight neonates - (Peer Reviewed Journal)
Gesteiro, E., Bastida, S., Vazquez-Valasco, M., Corella, D., Guillen, M., Ordovas, J.M., Sanchez-Muniz, F.J. 2011. Effects of APOA5 S19W polymorphism on growth, insulin sensitivity and lipoproteins in normoweight neonates. European Journal of Pediatrics. 170(12):1551-1558.
Differences in daily rhythms of wrist temperature between obese and normal-weight women: associations with metabolic syndrome features - (Peer Reviewed Journal)
Corbalan-Tutau, M., Madrid, J., Ordovas, J., Smith, C., Nicolas, F., Garaulet, M. 2011. Differences in daily rhythms of wrist temperature between obese and normal-weight women: associations with metabolic syndrome features. Society for Chronobiology International Conference Proceedings. 28(5):425-433.
Gene-gene and gene-environment interactions defining lipid-related traits - (Review Article)
Ordovas, J., Robertson, R., Ni Cleirigh, E. 2011. Gene-gene and gene-environment interactions defining lipid-related traits. Current Opinion in Lipidology. 22(2):129-136.
The PLIN4 variant rs8887 modulates obesity related phenotypes in humans through creation of a novel miR-522 seed site - (Peer Reviewed Journal)
Richardson, K., Louie-Gao, Q., Arnett, D., Parnell, L.D., Lai, C., Davalos, A., Fox, C., Demissie, S., Cupples, L., Fernandez-Hernando, C., Ordovas, J. 2011. The PLIN4 variant rs8887 modulates obesity related phenotypes in humans through creation of a novel miR-522 seed site. PLoS One. 6(4):e17944.
Dietary carbohydrate modifies the inverse association between saturated fat intake and cholesterol on very low-density lipoproteins - (Peer Reviewed Journal)
Frazier-Wood, A.C., Kabagambe, E.K., Borecki, I.B., Tiwari, H.K., Ordovas, J.M., Arnett, D.K. 2011. Dietary carbohydrate modifies the inverse association between saturated fat intake and cholesterol on very low-density lipoproteins. Lipid Insights. 4:7-15.
Short-term fenofibrate treatment reduces elevated plasma Lp-PLA2 mass and sVCAM-1 levels in a subcohort of hypertriglyceridemic GOLDN participants - (Peer Reviewed Journal)
Tsai, A.K., Steffen, B.T., Ordovas, J.M., Straka, R.J., Zhou, X., Hanson, N.Q., Arnett, D.K., Tsai, M.Y. 2011. Short-term fenofibrate treatment reduces elevated plasma Lp-PLA2 mass and sVCAM-1 levels in a subcohort of hypertriglyceridemic GOLDN participants. Translational Research. 58(2):99-105.
Prevalence of cardiovascular disease risk factors among older Puerto Rican adults living in Massachusetts - (Peer Reviewed Journal)
Van Rompay, M., Castaneda-Sceppa, C., Mckeown, N., Ordovas, J., Tucker, K. 2011. Prevalence of cardiovascular disease risk factors among older Puerto Rican adults living in Massachusetts. Journal of Immigrant and Minority Health. 13(5):825-833.
Interleukin 1B variant -1473G/C (rs1143623) influences triglyceride and interleukin 6 metabolism - (Peer Reviewed Journal)
Delgado-Lista, J., Garcia-Rios, A., Perez-Martinez, P., Solivera, J., Yubero-Serrano, E.M., Fuentes, F., Parnell, L.D., Shen, J., Gomez, P., Jimenez-Gomez, Y., Gomez-Luna, M.J., Marin, C., Belisle, S.E., Rodriguez-Cantalejo, F., Meydani, S.N., Ordovas, J.M., Perez-Jimenez, F., Lopez-Miranda, J. 2011. Interleukin 1B variant -1473G/C (rs1143623) influences triglyceride and interleukin 6 metabolism. Journal of Clinical Endocrinology and Metabolism. 96(5):E816-820.
Association of gene variants with lipid levels in response to fenofibrate is influenced by metabolic syndrome status - (Peer Reviewed Journal)
Feitosa, M., An, P., Ordovas, J., Ketkar, S., Hopkins, P., Straka, R., Arnett, D., Borecki, I. 2011. Association of gene variants with lipid levels in response to fenofibrate is influenced by metabolic syndrome status. Atherosclerosis. 215(2):435-439.
Apolipoprotein A-II polymorphism: relationships to behavioural and hormonal mediators of obesity - (Peer Reviewed Journal)
Smith, C.E., Ordovas, J.M., Sanchez-Moreno, C., Lee, Y., Garaulet, M. 2012. Apolipoprotein A-II polymorphism: relationships to behavioural and hormonal mediators of obesity. International Journal of Obesity. 36(1):130-136.
Apolipoprotein A-II polymorphism: relationships to behavioural and hormonal mediators of obesity - (Peer Reviewed Journal)
Smith, C., Ordovas, J., Sanchez-Moreno, C., Lee, Y., Garaulet, M. 2011. Apolipoprotein A-II polymorphism: relationships to behavioural and hormonal mediators of obesity. International Journal of Obesity. DOI: 10.1038/ijo.2011.24.
The folate hydrolase 1561 C>T polymorphism is associated with depressive symptoms in Puerto Rican adults - (Peer Reviewed Journal)
Ye, X., Lai, C., Crott, J., Troen, A., Ordovas, J., Tucker, K. 2011. The folate hydrolase 1561 C>T polymorphism is associated with depressive symptoms in Puerto Rican adults. Psychosomatic Medicine. 73(5):385-392.
Circulating plasma cholesteryl ester transfer protein activity and blood pressure tracking in the community - (Peer Reviewed Journal)
Zachariah, J.P., Pencina, M.J., Lyass, A., Kaur, G., D'Agostino, R.B., Ordovas, J.M., Vasan, R.S. 2011. Circulating plasma cholesteryl ester transfer protein activity and blood pressure tracking in the community. Journal of Hypertension. 29(5):863-868.
Apoa5 Gene Variation Interacts with Dietary Fat Intake to Modulate Obesity and Circulating Triglycerides in a Mediterranean Population - (Peer Reviewed Journal)
Sanchez-Moreno, C., Ordovas, J.M., Smith, C.E., Baraza, J.C., Lee, Y., Garaulet, M. 2011. APOA5 gene variation interacts with dietary fat intake to modulate obesity and circulating triglycerides in a Mediterranean population. Journal of Nutrition. 141(3):380-385.
Apoa5 Gene Variation Interacts with Dietary Fat Intake to Modulate Obesity and Circulating Triglycerides in a Mediterranean Population - (Peer Reviewed Journal)
Sanchez-Moreno, C., Ordovas, J., Smith, C., Baraza, J., Lee, Y., Garaulet, M. 2011. APOA5 gene variation interacts with dietary fat intake to modulate obesity and circulating triglycerides in a Mediterranean population. Journal of Nutrition. 141(3):380-385.
Association of the LCT-13910C>T polymorphism with obesity and its modulation by dairy products in a Mediterranean population - (Peer Reviewed Journal)
Corella, D., Arregui, M., Coltell, O., Portoles, O., Guillem-Saiz, P., Carrasco, P., Sorli, J., Ortega-Azorin, C., Gonzalez, J., Ordovas, J. 2011. Association of the LCT-13910C>T polymorphism with obesity and its modulation by dairy products in a Mediterranean population. Obesity. 19(8):1707-1714.
Association of the LCT-13910C>T polymorphism with obesity and its modulation by dairy products in a Mediterranean population - (Peer Reviewed Journal)
Corella, D., Arregui, M., Coltell, O., Portoles, O., Guillem-Saiz, P., Carrasco, P., Sorli, J.V., Ortega-Azorin, C., Gonzalez, J.I., Ordovas, J.M. 2011. Association of the LCT-13910C>T polymorphism with obesity and its modulation by dairy products in a Mediterranean population. Obesity. 19(8):1707-1714.
An approximation to the temporal order in endogenous circadian rhythms of genes implicated in human adipose tissue metabolism - (Peer Reviewed Journal)
Garaulet, M., Ordovas, J.M., Gomez-Abellan, P., Martinez, J.A., Madrid, J.A. 2011. An approximation to the temporal order in endogenous circadian rhythms of genes implicated in human adipose tissue metabolism. Journal of Cellular Physiology. 226(8):2075-2080.
Fads Gene Polymorphisms in Koreans: Association with _6 Polyunsaturated Fatty Acids in Serum Phospholipids, Lipid Peroxides, and Coronary Artery Disease - (Peer Reviewed Journal)
Kwak, J., Paik, J., Kim, O., Jang, Y., Lee, S., Ordovas, J., Lee, J. 2011. FADS gene polymorphisms in Koreans: association with _6 polyunsaturated fatty acids in serum phospholipids, lipid peroxides, and coronary artery disease. Atherosclerosis. 214(1):94-100.
Gene-gene and gene-environment interactions defining lipid-related traits - (Review Article)
Ordovas, J., Robertson, R., Cleirigh, E. 2011. Gene-gene and gene-environment interactions defining lipid-related traits. Current Opinion in Lipidology. 22(2):129-136.
Perilipin polymorphism interacts with saturated fat and carbohydrates to modulate insulin resistance - (Peer Reviewed Journal)
Smith, C.E., Arnett, D.K., Corella, D., Tsai, M.Y., Lai, C., Parnell, L.D., Lee, Y., Ordovas, J.M. 2012. Perilipin polymorphism interacts with saturated fat and carbohydrates to modulate insulin resistance. Nutrition, Metabolism and Cardiovascular Diseases. 22(5):449-455.
Epigenetics and cardiovascular disease - (Review Article)
Ordovas, J., Smith, C. 2010. Epigenetics and cardiovascular disease. Nature Reviews Cardiology. 7(9):510-519.
Association between the APOA2 promoter polymorphism and body weight in Mediterranean and Asia populations: replication of a gene-saturated fat interaction - (Peer Reviewed Journal)
Corella, D., Tai, E., Sorli, J., Chew, S., Coltell, O., Sotos-Prieto, M., Garcia-Rios, A., Estruch, R., Ordovas, J. 2011. Association between the APOA2 promoter polymorphism and body weight in Mediterranean and Asia populations: replication of a gene-saturated fat interaction. International Journal of Obesity. 35(5):666-675.
Apolipoprotein E polymorphisms and postprandial triglyceridemia before and after fenofibrate treatment in the Genetics of Lipid Lowering and Diet Network (GOLDN) Study - (Peer Reviewed Journal)
Irvin, M.R., Kabagambe, E.K., Tiwari, H.K., Parnell, L.D., Straka, R.J., Tsai, M., Ordovas, J.M., Arnett, D.K. 2010. Apolipoprotein E polymorphisms and postprandial triglyceridemia before and after fenofibrate treatment in the Genetics of Lipid Lowering and Diet Network (GOLDN) Study. Circulation: Cardiovascular Genetics. 3(5):462-467.
Urinary 8-hydroxy-2-deoxyguanosine and cognitive function in Puerto Rican adults - (Peer Reviewed Journal)
Gao, X., Lai, C., Scott, T., Shen, J., Cai, T., Ordovas, J.M., Tucker, K. 2010. Urinary 8-hydroxy-2-deoxyguanosine and cognitive function in Puerto Rican adults. American Journal of Epidemiology. 172(3):271-278.
The chronobiology, etiology and pathophysiology of obesity - (Review Article)
Garaulet, M., Ordovas, J., Madrid, J. 2010. The chronobiology, etiology and pathophysiology of obesity. International Journal of Obesity. 34(12):1667-1683.
Polymorphism at the TRIB1 gene modulates plasma lipid levels: insight from the Spanish familial hypercholesterolemia cohort study - (Peer Reviewed Journal)
Garcia-Rios, A., Perez-Martinez, P., Mata, P., Fuentes, F., Lopez-Miranda, J., Alonso, R., Caballero, J., Mata, N., Perez-Jimenez, F., Ordovas, J.M. 2010. Polymorphism at the TRIB1 gene modulates plasma lipid levels: insight from the Spanish familial hypercholesterolemia cohort study. Nutrition Metabolism and Cardiovascular Disease. 21(12):957-963.
The APOA1/C3/A4/A5 cluster and markers of allostatic load in the Boston Puerto Rican Health Study - (Peer Reviewed Journal)
Mattei, J., Demissie, S., Tucker, K.L., Ordovas, J.M. 2011. The APOA1/C3/A4/A5 cluster and markers of allostatic load in the Boston Puerto Rican Health Study. Nutrition Metabolism and Cardiovascular Disease. 21(11):862-870.
Expression of recombinant AccMRJP1 protein from royal jelly of Chinese honeybee in Pichia pastoris and its proliferation activity in an insect cell line - (Peer Reviewed Journal)
Shen, L., Zhang, W., Jin, F., Zhang, L., Chen, Z., Liu, L., Parnell, L.D., Lai, C., Li, D. 2010. Expression of recombinant AccMRJP1 protein from royal jelly of Chinese honeybee in Pichia pastoris and its proliferation activity in an insect cell line. Journal of Agricultural and Food Chemistry. 58(4):2266-2273.
Fatty acid interactions with genetic polymorphisms for cardiovascular disease - (Review Article)
Smith, C.E., Ordovas, J.M. 2010. Fatty acid interactions with genetic polymorphisms for cardiovascular disease. Current Opinion in Clinical Nutrition and Metabolic Care. 13(2):139-144.
Leptin receptor polymorphisms interact with polyunsaturated fatty acids to augment risk of insulin resistance and metabolic syndrome in adults - (Peer Reviewed Journal)
Phillips, C.M., Goumidi, L., Bertrais, S., Field, M.R., Ordovas, J.M., Cupples, L., Defoort, C., Lovegrove, J.A., Drevon, C.A., Blaak, E.E., Gibney, M.J., Kiec-Wilk, B., Karlstrom, B., Lopez-Miranda, J., Mcmanus, R., Hercberg, S., Lairon, D., Planells, R., Roche, H.M. 2010. Leptin receptor polymorphisms interact with polyunsaturated fatty acids to augment risk of insulin resistance and metabolic syndrome in adults. Journal of Nutrition. 140(2):238-244.
Association of vitamin B-6 status with inflammation, oxidative stress, and chronic inflammatory conditions: the Boston Puerto Rican Health Study - (Peer Reviewed Journal)
Shen, J., Lai, C., Mattei, J., Ordovas, J.M., Tucker, K.L. 2010. Association of vitamin B-6 status with inflammation, oxidative stress, and chronic inflammatory conditions: the Boston Puerto Rican Health Study. American Journal of Clinical Nutrition. 91(2):337-342.
Higher selenium status is associated with adverse blood lipid profile in British adults - (Peer Reviewed Journal)
Stranges, S., Laclaustra, M., Ji, C., Cappuccio, F.P., Vavas-Acien, A., Ordovas, J.M., Rayman, M., Guallar, E. 2010. Higher selenium status is associated with adverse blood lipid profile in British adults. Journal of Nutrition. 140(1):81-87.
Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms - (Peer Reviewed Journal)
Sofat, R., Hingorani, A.D., Smeeth, L., Humphries, S.E., Talmud, P.J., Cooper, J., Shah, T., Sandhu, M.S., Ricketts, S.L., Boekholdt, S., Wareham, N., Khaw, K., Kumari, M., Kivimaki, M., Marmot, M., Asselbergs, F.W., Van Der Harst, P., Dullaart, R.P., Navis, G., Van Veldhuisen, D.J., Van Gilst, W.H., Thompson, J.F., Mccaskie, P., Palmer, L.J., Arca, M., Quagliarini, F., Gaudio, C., Cambien, F., Nicaud, V., Poirer, O., Gudnason, V., Isaacs, A., Witteman, J.C., Van Duijn, C.M., Pencina, M., Vasan, R.S., D'Agostino, R.B., Ordovas, J.M., Li, T.Y., Kakko, S., Kauma, H., Savolainen, M.J., Kesaniemi, Y., Sandhofer, A., Paulweber, B., Sorli, J.V., Goto, A., Yokoyama, S., Okumura, K., Horne, B.D., Packard, C., Freeman, D., Ford, I., Sattar, N., Mccormack, V., Lawlor, D.A., Ebrahim, S., Smith, G.D., Kastelein, J.J., Deanfield, J., Casas, J.P. 2010. Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms. Circulation. 11(1):52-62.
Clock Gene Is Implicated in Weight Reduction in Obese Patients Participating in a Dietary Programme Based on the Mediterranean Diet - (Peer Reviewed Journal)
Garaulet, M., Corbalan, M., Madrid, J., Morales, E., Baraza, J.C., Lee, Y., Ordovas, J.M. 2010. CLOCK gene is implicated in weight reduction in obese patients participating in a dietary programme based on the Mediterranean diet. International Journal of Obesity. 34(3):516-523.
Circadian expression of adiponectin and its receptors in human adipose tissue - (Peer Reviewed Journal)
Gomez-Abellan, P., Gomez-Santos, C., Madrid, J., Milagro, F.I., Campion, J., Martinez, J., Ordovas, J.M., Garaulet, M. 2010. Circadian expression of adiponectin and its receptors in human adipose tissue. Endocrinology. 151(1):115-122.
Consumption of diets with different type of fat influences triacylglycerols-rich lipoproteins particle number and size during the postprandial state - (Peer Reviewed Journal)
Perez-Martinez, P., Ordovas, J.M., Garcia-Rios, A., Delgado-Lista, J., Delgado-Casado, N., Cruz-Teno, C., Camargo, A., Yubero-Serrano, E., Rodriguez, F., Perez-Jimenez, F., Lopez-Miranda, J. 2011. Consumption of diets with different type of fat influences triacylglycerols-rich lipoproteins particle number and size during the postprandial state. Nutrition Metabolism and Cardiovascular Disease. 21(1):39-45.
Serum selenium concentrations and diabetes in U.S. adults: National Health and Nutrition Examination Survey (NHANES) 2003-2004 - (Peer Reviewed Journal)
Laclaustra, M., Navas-Acien, A., Stranges, S., Ordovas, J., Guallar, E. 2009. Serum selenium concentrations and diabetes in U.S. adults: National Health and Nutrition Examination Survey (NHANES) 2003-2004. Environmental Health Perspectives. 117(9):1409-1413.
The effects of ABCG5/G8 polymorphisms on HDL-cholesterol concentrations depend on ABCA1 genetic variants in the Boston Puerto Rican health study - (Peer Reviewed Journal)
Junyent, M., Tucker, K., Smith, C., Lane, J., Mattei, J., Lai, C., Parnell, L.D., Ordovas, J. 2010. The effects of ABCG5/G8 polymorphisms on HDL-cholesterol concentrations depend on ABCA1 genetic variants in the Boston Puerto Rican health study. Nutrition Metabolism and Cardiovascular Disease. 20(8):558-566.
Genetic APOC3 mutation, serum triglyceride concentrations, and coronary heart disease - (Review Article)
Tsai, M.Y., Ordovas, J. 2009. Genetic APOC3 mutation, serum triglyceride concentrations, and coronary heart disease. Clinical Chemistry. 55(7):1274-1276.
Integrating environment and disease into "omic" analysis - (Review Article)
Ordovas, J. 2009. Integrating environment and disease into "omic" analysis. Revista Espanola De Cardiologia. 62(2):17-22.
A composite scoring of genotypes discriminates coronary heart disesase risk beyond conventional risk factors in the Boston Puerto Rican Health Study - (Peer Reviewed Journal)
Junyent, M., Tucker, K., Shen, J., Lee, Y., Smith, C., Mattei, J., Lai, C., Parnell, L.D., Ordovas, J. 2010. A composite scoring of genotypes discriminates coronary heart disesase risk beyond conventional risk factors in the Boston Puerto Rican Health Study. Nutrition Metabolism and Cardiovascular Disease. 20(3):157-164.
Genetic influences on blood lipids and cardiovascular disease risk: tools for primary prevention - (Review Article)
Ordovas, J. 2009. Genetic influences on blood lipids and cardiovascular disease risk: tools for primary prevention. American Journal of Clinical Nutrition. 89:1509S-1507S.
Impact of genetic and environmental factors on hsCRP concentrations and response to therapeutic agents - (Review Article)
Shen, J., Ordovas, J.M. 2008. Impact of genetic and environmental factors on hsCRP concentrations and response to therapeutic agents. Clinical Chemistry. 55:256-264.
Serum lipid and antioxidant responses in hypercholesterolemic men and women receiving plant sterol esters vary by apolipoprotein E genotype - (Peer Reviewed Journal)
Sanchez-Muniz, F., Schaefer, E.J., Ordovas, J. 2008. Serum lipid and antioxidant responses in hypercholesterolemic men and women receiving plant sterol esters vary by apolipoprotein E genotype. Journal of Nutrition. 139:13-19.
Last Modified: 8/19/2014
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