Publications (Clicking on the reprint icon will take you to the publication reprint.)

Apo-10'-lycopenoic acid, a lycopene 1 metabolite, increases sirtuin 1 mRNA and protein levels and decreases hepatic fat accumulation in ob/ob mice - (Peer Reviewed Journal)

Chung, J., Koo, K., Lian, F., Hu, K., Ernst, H., Wang, X. 2012. Apo-10'-lycopenoic acid, a lycopene 1 metabolite, increases sirtuin 1 mRNA and protein levels and decreases hepatic fat accumulation in ob/ob mice. Journal of Nutrition. 142(3):405-410.

Consumption of lycopene inhibits the growth and progression of colon cancer in a mouse xenograft model - (Peer Reviewed Journal)

Tang, F., Pai, M., Wang, X. 2011. Consumption of lycopene inhibits the growth and progression of colon cancer in a mouse xenograft model. Journal of Agricultural and Food Chemistry. 59(16):9011-9021.

Combined alpha-tocopherol and ascorbic acid protects against smoke-induced lung squamous metaplasia in ferrets - (Peer Reviewed Journal)

Kim, Y., Chongviriyaphana, N., Liu, C., Russel, R., Wang, X. 2012. Combined alpha-tocopherol and ascorbic acid protects against smoke-induced lung squamous metaplasia in ferrets. Lung Cancer. 75:15-23.

Long term ethanol consumption promotes hepatic tumorigenesis but impairs normal hepatocyte proliferation in rats - (Peer Reviewed Journal)

Chavez, P., Chung, J., Liu, C., Paiva, S., Seitz, H., Wang, X., Lian, F. 2011. Long term ethanol consumption promotes hepatic tumorigenesis but impairs normal hepatocyte proliferation in rats. Journal of Nutrition. 141(6):1049-1055 PMID 21490289.

Beta-Cryptoxanthin supplementation prevents cigarette smoke-induced lung inflammation, oxidative damage and squamous metaplasia in ferrets - (Peer Reviewed Journal)

Liu, C., Bronson, R.T., Russell, R., Wang, X. 2011. Beta-Cryptoxanthin supplementation prevents cigarette smoke-induced lung inflammation, oxidative damage and squamous metaplasia in ferrets. Cancer Prevention Research. PMID:21421799.

Enzymatic formation of apo-carotenoids from the xanthophyll carotenoids lutein, zeaxanthin and b-cryptoxanthin by ferret carotene-9, 10-monooxygenase - (Peer Reviewed Journal)

Mein, J., Dolnikowski, G., Hansgeorg, E., Russel, R., Wang, X. 2011. Enzymatic formation of apo-carotenoids from the xanthophyll carotenoids lutein, zeaxanthin and b-cryptoxanthin by ferret carotene-9, 10-monooxygenase. Archives Of Biochemistry and Biophysics. 506:109-121 PMID 21081106.

Chronic alcohol intake up-regulates hepatic expressions of carotenoid cleavage enzymes and peroxisomal proliferator-activated receptors in rats - (Peer Reviewed Journal)

Luvizotto, R., Nascimento, A., Veeramachnei, S., Liu, C., Wang, X. 2010. Chronic alcohol intake up-regulates hepatic expressions of carotenoid cleavage enzymes and peroxisomal proliferator-activated receptors in rats. Journal of Nutrition. 140(10):1808-1814. PMID 20702748.

Cyanidin-3-O-beta-glucoside inhibits LPS-induced expression of inflammatory mediators through decreasing IkBa Phosphorylation in THP-1 Cells - (Peer Reviewed Journal)

Zhang, Y., Lian, F., Zhu, Y., Xia, M., Wang, Q., Ling, W., Wang, X. 2010. Cyanidin-3-O-beta-glucoside inhibits LPS-induced expression of inflammatory mediators through decreasing IkBa Phosphorylation in THP-1 Cells. Inflammation Research. 59(9):723-730.

Biological activities of carotenoid metabolites - (Book / Chapter)

Wang, X. 2009. Biological activities of carotenoid metabolites. In: Britton, A., Jensen, B., Pfander, D., editors. Carotenoids. 5th edition. Basel, Switzerland: Verlag Press. p.383-408.

Nonalcoholic steatohepatitis induced by a high-fat diet promotes diethylnitrosamine initiated early hepatocarcinogenesis in rats - (Peer Reviewed Journal)

Wang, Y., Ausman, L.M., Greenberg, A.S., Russell, R.M., Wang, X. 2009. Nonalcoholic steatohepatitis induced by a high-fat diet promotes diethylnitrosamine initiated early hepatocarcinogenesis in rats. International Journal of Cancer. 124(3):540-546.

Oxidative metabolites of lycopene and their biological functions - (Book / Chapter)

Mein, J., Wang, X. 2009. Oxidative metabolites of lycopene and their biological functions. In: Landrum, M., editor. Carotenoids. New York, NY: Taylor and Francis. p.417-436.