1a.Objectives (from AD-416):
Enhance communication and interaction between the ARS/BHNRC and the NIH's National Center for Complementary and Alternative Medicine reseach communities to facilitate research on probiotics in human subjects, and to integrate results from that research into an improved understanding of the mechanism of action of probiotics and their effects on human health.
1b.Approach (from AD-416):
Each Agency has existing programs and resources for facilitating reearch and technology development. Research facilitated by this MOU will be complementary to studies supported by the ARS/BHNRC and NIH/NCCAM at the agencies' intramural and extramural laboratories.
During FY 2013, transcriptomic analysis of whole blood cells from 14 elderly subjects from an open label study consuming probiotic strain Lactobacillus rhamnossus (LGG) were analyzed. This clinical study was conducted at Massachusetts General Hospital and funded through an Administrative Supplement from Consortium/contractual USDA/ARS and University of MD.