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Research Project: NUTRITION, OBESITY, CARDIOVASCULAR HEALTH AND GENOMICS

Location: Human Nutrition Research Center on Aging

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)

Advances in technologies and study design - (Book / Chapter)
Parnell, L.D. 2012. Advances in technologies and study design. In: Bouchard, C., Ordovas, J.M., editors. Progress in Molecular Biology and Translational Science. New York, NY: Elsevier Inc. 108:17-50.
BioStar: an online question & answer resource for the bioinformatics community - (Peer Reviewed Journal)
Parnell, L.D., Lindenbaum, P., Shameer, K., Dall'Olio, G.M., Swan, D.C., Jensen, L.J., Cockell, S.J., Pedersen, B.P., Mangan, M.E., Miller, C., Albert, I. 2011. BioStar: an online question & answer resource for the bioinformatics community. PLoS Computational Biology. 7:e1002216.
Glucokinase regulatory proten genetic variant interacts with omega-3 PUFA to influence insulin resistance and inflammation in metabolic syndrome - (Peer Reviewed Journal)
Perez-Martinez, P., Delgado-Lista, J., Garcia-Rios, A., Mcmonagle, J., Gulseth, H.L., Ordovas, J.M., Shaw, D.I., Karlstrom, B., Kiec-Wilk, B., Blaak, E.E., Helal, O., Malczewska-Malec, M., Defoort, C., Riserus, U., Saris, W., Lovegrove, J.A., Drevon, C.A., Roche, H.M., Lopez-Miranda, J. 2011. Glucokinase regulatory proten genetic variant interacts with omega-3 PUFA to influence insulin resistance and inflammation in metabolic syndrome. PLoS One. 6(6):e20555.
A database of gene-environment interactions pertaining to blood lipid traits, cardiovascular disease and type 2 diabetes - (Peer Reviewed Journal)
Lee, Y., Lai, C., Ordovas, J.M., Parnell, L.D. 2011. A database of gene-environment interactions pertaining to blood lipid traits, cardiovascular disease and type 2 diabetes. Journal of Data Mining in Genomics & Proteomics. 2:106. DOI:10.4172/2153-0602.1000106.
Interactions between genetic variants of folate metabolism genes and lifestyle affect plasma homocysteine concentrations in the Boston Puerto Rican Population - (Peer Reviewed Journal)
Huang, T., Tucker, K., Lee, Y., Crott, J., Parnell, L.D., Shen, J., Smith, C., Ordovas, J., Li, D., Lai, C. 2011. Interactions between genetic variants of methionine metabolism genes and lifestyle affect plasma homocysteine concentrations in the Boston Puerto Rican Population. Molecular Nutrition and Food Research. DOI: 10.1017/S1368980011000140.
Gene variations of nitric oxide synthase regulate the effects of a saturated fat rich meal on endothelial function - (Peer Reviewed Journal)
Delgado-Lista, J., Fuentes, F., Jimenez-Gomez, Y., Perez-Martinez, P., Gomez-Luna, M.J., Parnell, L.D., Marin, C., Lai, C., Perez-Jimenez, F., Ordovas, J.M., Lopez-Miranda, J. 2010. Gene variations of nitric oxide synthase regulate the effects of a saturated fat rich meal on endothelial function. Clinical Nutrition. 30(2):234-238.
Apolipoprotein B genetic variants modify the response to fenofibrate: a GOLDN study - (Peer Reviewed Journal)
Wojczynski, M.K., Gao, G., Borecki, I., Hopkins, P.N., Parnell, L.D., Lai, C., Ordovas, J.M., Arnett, D.K. 2010. Apolipoprotein B genetic variants modify the response to fenofibrate: a GOLDN study. Journal of Lipid Research. 51(11):3316-3323.
Drosophila lacks C20 and C22 polyunsaturated fatty acids - (Peer Reviewed Journal)
Shen, L., Lai, C., Feng, X., Parnell, L.D., Wang, J., Li, D., Ordovas, J.M., Kang, J. 2010. Drosophila lacks C20 and C22 polyunsaturated fatty acids. Journal of Lipid Research. 51(10)2985-2992.
ABCA1 gene variants regulate posprandial lipid metabolism in healthy men - (Peer Reviewed Journal)
Delgado-Lista, J., Perez-Martinez, P., Perez-Jiminez, F., Garcia-Rios, A., Fuentes, F., Marin, C., Gomez-Luna, P., Camargo, A., Parnell, L.D., Ordovas, J.M., Lopez-Miranda, J. 2010. ABCA1 gene variants regulate posprandial lipid metabolism in healthy men. Arteriosclerosis Thrombosis and Vascular Biology. 30(5):1051-1057.
Adaptive genetic variation and heart disease risk - (Review Article)
Parnell, L.D., Lee, Y., Lai, C. 2010. Adaptive genetic variation and heart disease risk. Current Opinion in Lipidology. 21(2):116-122.
PER2 variants are associated with abdominal obesity, psycho-behavioral factors and attrition in the dietary treatment of obesity - (Peer Reviewed Journal)
Garaulet, M., Corbalan-Tutau, D., Madrid, J.A., Baraza, J.C., Parnell, L.D., Lee, Y., Ordovas, J.M. 2010. PER2 variants are associated with abdominal obesity, psycho-behavioral factors and attrition in the dietary treatment of obesity. Journal of American Dietetic Association. 110(6):917-921.
Gene-environment interactions and the impact on obesity and lipid profile phenotypes - (Review Article)
Parnell, L.D. 2009. Gene-environment interactions and the impact on obesity and lipid profile phenotypes. Clinical Lipidology. 4:104-107.

   

 
Project Team
Swietlik, Dariusz
Lai, Chao Qiang
Parnell, Laurence
 
Project Annual Reports
  FY 2012
  FY 2011
  FY 2010
  FY 2009
 
Publications
   Publications
 
Related National Programs
  Human Nutrition (107)
 
Related Projects
   NUTRITION, OBESITY, CARDIOVASCULAR HEALTH AND GENOMICS
   GENE EXPRESSION AND SYSTEMS-BASED ANALYSIS TO PREDICT GENE-ENVIRONMENT INTERACTIONS
   COMBINING GENE EXPRESSION DATA AND SYSTEMS-BASED NETWORK ANALYSIS TO PREDICT GENE-ENVIRONMENT INTERACTIONS
 
 
Last Modified: 05/18/2013
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