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Research Project:
LINKING FOODS, BEHAVIOR AND METABOLISM TO PROMOTE A HEALTHY BODY WEIGHT
Location: Obesity and Metabolism Research Unit
Publications
(Clicking on the reprint icon
will take you to the publication reprint.)
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Plasma oxylipin profiling identifies polyunsaturated vicinal diols as responsive to arachidonic acid and docosahexaenoic acid intake in growing piglets
- (Peer Reviewed Journal)
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| Bruins, M.J., Dane, A.D., Strassburg, K., Vreeken, R.J., Newman, J.W., Salem, Jr, N., Tyburczy, C., Brenna, J.T. 2013. Plasma oxylipin profiling identifies polyunsaturated vicinal diols as responsive to arachidonic acid and docosahexaenoic acid intake in growing piglets. Journal of Lipid Research. PMID: 23543770. |
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Regulation of adipose branched chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity
- (Peer Reviewed Journal)
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| (13-Mar-13) |
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Structured variable selection with q-values
- (Peer Reviewed Journal)
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| (04-Mar-13) |
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Having your cake and eating it too: A habit of comfort food may link chronic social stress exposure and acute stress-induced cortisol hyporesponsiveness.
- (Peer Reviewed Journal)
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| (25-Feb-13) |
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Leucine and protein metabolism in obese zucker rats
- (Peer Reviewed Journal)
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| (14-Feb-13) |
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Estimating dietary costs of low-income women in California: A comparison of two approaches
- (Peer Reviewed Journal)
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| (10-Dec-12) |
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Executive function and emotional arousal are related to eating in the absence of hunger in preschool children
- (Peer Reviewed Journal)
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| (26-Nov-12) |
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Increased lipolysis and altered lipid homeostasis protect
y-synuclein null mutant mice from diet-induced obesity
- (Peer Reviewed Journal)
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| (12-Nov-12) |
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Dairy food consumption and meal-induced cortisol response interact to influence weight loss in overweight women undergoing a 12-week meal-controlled weight loss intervention
- (Peer Reviewed Journal)
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| (22-Oct-12) |
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Type 2 diabetes associated changes in the plasma non-esterified fatty acids, oxylipins and endocannabinoids.
- (Peer Reviewed Journal)
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| (01-Oct-12) |
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Increased Phosphoenolpyruvate Carboxykinase (PEPCK) Gene Expression and Steatosis During Hepatitis C Virus (HCV) Subgenome Replication: Role of Nonstructural Component-5A (NS5A) and CCAAT/Enhancer Binding Protein ß (C/EBPß)
- (Peer Reviewed Journal)
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| Qadri, I., Choudhury, M., Rahman, S.M., Knotts, T.A., Janssen, R.C., Schaack, J., Iwahashi, M., Puljak, L., Simon, F.R., Kilic, G., Fitz, J.G., Friedman, J.E. 2012. Increased Phosphoenolpyruvate Carboxykinase (PEPCK) Gene Expression and Steatosis During Hepatitis C Virus (HCV) Subgenome Replication: Role of Nonstructural Component-5A (NS5A) and CCAAT/Enhancer Binding Protein ß (C/EBPß). Journal of Biological Chemistry. 10.1074. |
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Energy assessment: physical activity
- (Book / Chapter)
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| (31-Aug-12) |
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Daily consumption of orange-fleshed sweet potato with added fat tends to increase total body vitamin A pool size in vitamin A depleted Bangladeshi women
- (Peer Reviewed Journal)
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| (09-Aug-12) |
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IRF-1 and miRNA126 modulate inflammatory VCAM-1 expression in response to a high fat meal
- (Peer Reviewed Journal)
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| (07-Aug-12) |
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A dairy-based high calcium diet improves glucose homeostasis and reduces steatosis in the context of pre-existing obesity
- (Peer Reviewed Journal)
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| (13-Jul-12) |
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imDEV: a graphical user interface to R multivariate analysis tools in Microsoft Excel
- (Peer Reviewed Journal)
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| Grapov, D., Newman, J.W. 2012. imDEV: a graphical user interface to R multivariate analysis tools in Microsoft Excel. Oxford University Press. doi:10.1093. |
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Quantitative profiling of oxylipins through comprehensive lc-ms/ms analysis: Application in cardiac surgery
- (Peer Reviewed Journal)
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| Strassburg, K., Pedersen, T.L., Huijbrechts, A.M., Kortekaas, K., Lindeman, J., Dane, A., Berger, R., Brenkman, A., Hankemeier, T., Van Duynhoven, J., Kalkhoven, E., Newman, J.W., Vreeken, R. 2012. Quantitative profiling of oxylipins through comprehensive lc-ms/ms analysis: Application in cardiac surgery . Analytical and Bioanalytical Chemistry. 1413-26. |
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Basal omega-3 fatty acid status affects fatty acid and oxylipin responses to high-dose n3-HUFA in healthy volunteers
- (Peer Reviewed Journal)
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| Keenan, A.H., Pedersen, T.L., Fillaus, K., Larson, M.K., Shearer, G.C., Newman, J.W. 2012. Basal omega-3 fatty acid status affects fatty acid and oxylipin responses to high-dose n3-HUFA in healthy volunteers. Journal of Lipid Research. doi: 10.1194. |
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Variations in metabolic responses to meal challenges differing in glycemic index in healthy women: Is it meaningful?
- (Peer Reviewed Journal)
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| Krishnan, S., Newman, J.W., Hembrooke, T.A., Keim, N.L. 2012. Variations in metabolic responses to meal challenges differing in glycemic index in healthy women: Is it meaningful?. Nutrition and Metabolism. 9:26. |
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Variation in metabolic responses to meal challenges differing in glycemic index in healthy women: Is it meaningful?
- (Peer Reviewed Journal)
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| Krishnan, S., Newman, J.W., Hembrooke, T.A., Keim, N.L. 2012. Variation in metabolic responses to meal challenges differing in glycemic index in healthy women: Is it meaningful?. Journal of Nutrition and Metabolism. 9(1):26. |
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Skipping breakfast is associated with lower physical activity energy expenditure in young healthy women
- (Abstract Only)
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| Marquez, A.P., Forester, S., Witbracht, M., Campbell, C., Gustafson, M., Keim, N.L. 2012. Skipping breakfast is associated with lower physical activity energy expenditure in young healthy women. Journal of Federation of American Societies for Experimental Biology. 820.21. |
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Increased dietary saturated fat intake is negatively associated
with compliance to exercise regimen and improvement in
fitness parameters.
- (Abstract Only)
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| Krishnan, S., Gustafson, M., Sheets, C., Souza, E., Keim, N.L. 2012. Increased dietary saturated fat intake is negatively associated with compliance to exercise regimen and improvement in fitness parameters.. Journal of Federation of American Societies for Experimental Biology. 257.4. |
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Within subject variation of satiety hormone responses to a
standard lunch
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| Forester, S.M., Witbracht, M., Horn, W.F., Keim, N.L., Laugero, K.D. 2012. Within subject variation of satiety hormone responses to a standard lunch. Journal of Federation of American Societies for Experimental Biology. 639.5. |
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A high calcium diet containing nonfat dry milk reduces weight gain and associated adipose tissue inflammation in diet-induced obese mice when compared to high calcium alone
- (Peer Reviewed Journal)
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| Thomas, A.P., Dunn, T.N., Drayton, J.B., Oort, P.J., Adams, S.H. 2012. A high calcium diet containing nonfat dry milk reduces weight gain and associated adipose tissue inflammation in diet-induced obsed mice when comparated to high calcium alone. Nutrition and Metabolism. 9:3. |
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A dairy-based high calcium diet improves glucose homeostasis and reduces further weight gain in high fat fed mice in the context of pre-existing obesity
- (Peer Reviewed Journal)
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| Thomas, A.P., Dunn, T.N., Drayton, J.B., Oort, P.J., Adams, S.H. 2012. A dairy-based high calcium diet improves glucose homeostasis and reduces further weight gain in high fat fed mice in the context of pre-existing obesity. Nutrition and Metabolism. 10.1186/1743-7075-9-3. |
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Stress and food intake: What's the deal with your meal?
- (Peer Reviewed Journal)
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| Laugero, K.D., Tryon, M.S. 2011. Stress and food intake: What's the deal with your meal?. CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources. doi: 10.1079/PAVSNNR20116034. |
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Circulating concentrations of monocyte chemoattranctant protein-1, plasminogen activator inhibitor-1, & soluble leukocyte adhesion molecule-1 in overweight/obese men/women consuming fructose-or glucose-sweetened beverages
- (Peer Reviewed Journal)
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| Cox, C.L., Stanhope, K.L., Marc Schwarz, J., Graham, J.L., Griffen, S.C., Bremer, A.A., Berglund, L., Mcgahan, J.P., Beysen, C., Keim, N.L., Havel, P.J. 2011. Circulating concentrations of monocyte chemoattranctant protein-1, plasminogen activator inhibitor-1, & soluble leukocyte adhesion molecule-1 in overweight/obese men/women consuming fructose-or glucose-sweetened beverages. Journal of Clinical Endocrinology and Metabolism. 96(12):E2034-E2038. |
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Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant states
- (Peer Reviewed Journal)
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| Adams, S.H. 2011. Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant states 1,2. Advances in Nutrition. doi:10.3945. |
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Comparative effects of fructose and glucose on lipogenic gene expression and intermediary metabolism in HepG2 liver cells
- (Peer Reviewed Journal)
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| Hirahatake, K.M., Meissen, J., Fiehn, O., Adams, S.H. 2011. Comparative effects of fructose and glucose on lipogenic gene expression and intermediary metabolism in HepG2 liver cells. PLoS One. 10.1371. |
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Assessing face validity of a physical activity questionnaire for Spanish-speaking women in California
- (Peer Reviewed Journal)
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| Banna, J.C., Keim, N.L., Townsend, M.S. 2011. Assessing face validity of a physical activity questionnaire for Spanish-speaking women in California. Journal of Extension. Vol.49:5. |
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Consumption of fructose-sweetened beverages for 10 weeks reduces net fat oxidation and energy expenditure in overweight/obese men and women
- (Peer Reviewed Journal)
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| Cox, C., Stanhope, K.L., Schwarz, J.M., Graham, J.L., Havel, P.J., Keim, N.L. 2011. Consumption of fructose-sweetened beverages for 10 weeks reduces net fat oxidation and energy expenditure in overweight/obese men and women. American Journal of Clinical Nutrition. Eur J Clin Nutr. 2012 Feb;66(2):201-8. |
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Consumption of fructose and high fructose corn syrup increase postprandial triglycerides, LDL-cholestrol, and apolipoprotein-b in young men and women
- (Peer Reviewed Journal)
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| Stanhope, K., Bremer, A.A., Natkajima, K., Ito, Y., Nakano, T., Chen, G., Fong, T.H., Lee, V., Menorca, R., Keim, N.L., Havel, P.J. 2011. DIFFERENTIAL EFFECTS OF CONSUMING GLUCOSE-, FRUCTOSE-, AND HIGH FRUCTOSE CORN SYRUP-SWEETENED BEVERAGES FOR 2 WEEKS ON FASTING AND POSTPRANDIAL LIPID AND LIPOPROTEIN PROFILES IN YOUNG MEN AND WOMEN. Journal of Clinical Endocrinology and Metabolism. 96(10):E1596-1605. |
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Performance on the Iowa gambling task is related to magnitude of weight loss and salivary cortisol in a diet-induced weight loss intervention in overweight women
- (Peer Reviewed Journal)
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| Witbracht, M.G., Laugero, K.D., Van Loan, M.D., Adams, S.H., Keim, N.L. 2011. PERFORMANCE ON THE IOWA GAMBLING TASK IS RELATED TO MAGNITUDE OF WEIGHT LOSS AND SALIVARY CORTISOL IN A DIET-INDUCED WEIGHT LOSS INTERVENTION IN OVERWEIGHT WOMEN. Physiology and Behavior. 10.1016/j.physbeh.2011.04.035. |
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A null-mutation in the Znt7 gene accelerates prostate tumor formation in a transgenic adenocarcinoma mouse prostate model
- (Peer Reviewed Journal)
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| Tepaamorndech, S., Huang, L., Kirschke, C.P. 2011. A null-mutation in the Znt7 gene accelerates prostate tumor formation in a transgenic adenocarcinoma mouse prostate model. Cancer Letters. 308 (2011) 33-42. |
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Metabolic responses to prolonged consumption of glucose- and fructose-sweetened beverages are not associated with postprandial or 24-hour glucose and insulin excursions
- (Peer Reviewed Journal)
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| Stanhope, K., Griffin, S.C., Bremer, A.A., Schaefer, E., Natkajima, K., Schwarz, J.M., Beysen, C., Berglund, L., Keim, N.L., Havel, P.J. 2011. METABOLIC RESPONSES TO PROLONGED CONSUMPTION OF GLUCOSE- AND FRUCTOSE-SWEETENED BEVERAGES ARE NOT ASSOCIATED WITH POSTPRANDIAL OR 24-HOUR GLUCOSE AND INSULIN EXCURSIONS. American Journal of Clinical Nutrition. 94:112-119. |
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Decreased expression of adipose CD36 and FATP1 are associated with increased plasma nonesterified fatty acids during prolonged fasting in northern elephant seal pups (Mirounga angustirostris)
- (Peer Reviewed Journal)
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| Viscarra, J.A., Vazquez-Medina, J.P., Rodriguez, R., Champagne, C.D., Adams, S.H., Crocker, D.E., Ortiz, R.M. 2012. Decreased expression of adipose CD36 and FATP1 are associated with increased plasma nonesterified fatty acids during prolonged fasting in northern elephant seal pups (Mirounga angustirostris) . Experimental Biology. 215(Pt 14):2455-64. |
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An optimized method for measuring methylmalonic acid in low volumes of serum using UPLC-MS/MS
- (Peer Reviewed Journal)
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| Pedersen, T.L., Keyes, W.R., Shahab-Ferdows, S., Allen, L.H., Newman, J.W. 2011. An Optimized Method for Measuring Methylmalonic Acid in Low Volumes of Serum Using UPLC-MS/MS. Journal of Chromatography. B. 879, 1502-6. |
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Effects of industrially produced trans fat on markers of systemic inflammation: evidence from a randomized trial in women
- (Peer Reviewed Journal)
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| Bendensen, N.T., Stender, S., Szecsi, P.B., Pedersen, S.B., Basu, S., Hellgren, L.I., Newman, J.W., Larsen, T.M., Haugaard, S.B., Astrup, A. 2011. Effects of industrially produced trans fat on markers of systemic inflammation: evidence from a randomized trial in women. Journal of Lipid Research. doi 10.1194/jlr.M014738. |
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Inflammatory phenotyping identifies CD11d as a gene markedly induced in white adipose tissue in obesity
- (Peer Reviewed Journal)
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| Thomas, A.P., Dunn, T.N., Oort, P.J., Grino, M., Adams, S.H. 2011. Inflammatory phenotyping identifies CD11d as a gene markedly induced in white adipose tissue in obesity. Journal of Nutrition. 1172-1180. |
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The human serum metabolome
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| Psychogios, N., Hau, D.D., Peng, J., Guo, A., Mandal, R., Bouatra, S., Sinelnikov, I., Krishnamurthy, R., Eisner, R., Gautam, B., Young, N., Xia, J., Knox, C., Dong, E., Huang, P., Hollander, Z., Pedersen, T.L., Smith, S.R., Bamforth, F., Greiner, R., Mcmanus, B., Newman, J.W., Goodfriend, T., Wishart, D.S. 2011. THE HUMAN SERUM METABOLOME. PLoS One. 6(2): e16957. |
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Translating the Dietary Guidelines for Americans 2010 to Bring About Real Behavior Change
- (Peer Reviewed Journal)
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| Rowe, S., Alexander, N., Almeida, N., Black, R., Burns, R., Bush, L., Crawford, P., Keim, N.L., Kris-Etherton, P., Weaver, C. 2011. Translating the Dietary Guidelines for Americans 2010 to Bring About Real Behavior Change. Journal of American Dietetic Association. 111(1):28-39. |
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Food science challenge: Translating the Dietary Guidelines for Americans to Bring About Real Behavior Change
- (Peer Reviewed Journal)
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| 2011. Food science challenge: Translating the dietary guidelines for americans to bring about real behavior change. Journal of Food Science. 76:R29-37. |
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Effects of dynamic exercise on plasma arachidonic acid epoxides and diols in human volunteers
- (Peer Reviewed Journal)
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| Giordano, R.M., Newman, J.W., Pedersen, T.L., Ramos, M.I., Stebbins, C. 2011. Effects of dynamic exercise on plasma arachidonic acid epoxides and diols in human volunteers. American Journal of Clinical Nutrition. doi: 21, 471-479. |
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Plasma omega 3 polyunsaturated fatty acid status and monounsaturated fatty acids are altered by chronic social stress and predict endocrine responses to acute stress in titi monkeys
- (Peer Reviewed Journal)
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| Laugero, K.D., Smilowitz, J.T., German, J.B., Jarcho, M.R., Mendoza, S.P., Bales, K.L. 2011. Plasma omega 3 polyunsaturated fatty acid status and monounsaturated fatty acids are altered by chronic social stress and predict endocrine responses to acute stress in titi monkeys. Prostaglandins Leukotrienes and Essential Fatty Acids. 84(3-4):71-8. |
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Relationship between perceived stress and dietary and activity patterns in older adults participating in the Boston Puerto Rican Health Study
- (Peer Reviewed Journal)
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| Laugero, K.D., Falcon, L.M., Tucker, K.L. 2011. Relationship between perceived stress and dietary and activity patterns in older adults participating in the Boston Puerto Rican Health Study. Appetite. 56:194-204. |
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Associations between life stress and patterns of food intake and physical activity in the Boston Puerto Rican health study
- (Peer Reviewed Journal)
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| Laugero, K.D., Falcon, L.M., Tucker, K.L. 2010. Associations Between Life Stress and Patterns of Food Intake and Physical Activity in the Boston Puerto Rican Health Study. American Journal of Clinical Nutrition. 56(1):194-204. |
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Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and Type 2 diabetic obese African-American women
- (Peer Reviewed Journal)
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| Fiehn, O., Garvey, W., Newman, J.W., Lok, K.H., Hoppel, C.L., Adams, S.H. 2010. Plasma Metabolomic Profiles Reflective of Glucose Homeostasis in Non-Diabetic and Type 2 Diabetic Obese African-American Women. PLoS One. Vol.5(12): e15234. |
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Brain functional magnetic resonance imaging response to glucose and fructose infusions in humans
- (Peer Reviewed Journal)
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| Purnell, J.Q., Klopfenstein, B.A., Stevens, A.A., Havel, P.J., Adams, S.H., Dunn, T.N., Krisky, C., Rooney, W.D. 2011. Brain fMRI response to glucose and fructose infusions in humans. Diabetes Obesity and Metabolism. 13(3):229-34. |
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Web-enabled and improved software tools and data are needed to measure nutrient intakes and physical activity for personalized health research
- (Peer Reviewed Journal)
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| Stumbo, P.J., Weiss, R., Newman, J.W., Pennington, J.A., Tucker, K.L., Wiesenfield, P., Illner, A., Klurfeld, D.M., Kaput, J. 2010. Web-enabled and improved software tools and data are needed to measure nutrient intakes and physical activity for personalized health research. Journal of Nutrition. 140:2104-2115. |
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Conjugated Linoleic Acids and Inflammation: Isomer and Tissue Specific Responses
- (Review Article)
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| (26-Jul-10) |
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Over-expression of ZnT7 increases insulin synthesis and secretion in pancreatic beta-cells by promoting insulin gene transcription
- (Peer Reviewed Journal)
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| Huang, L., Mi, Y., Kirschke, C.P. 2010. Over-expression of ZnT7 increases insulin synthesis and secretion in pancreatic beta-cells by promoting insulin gene transcription. Experimental Cell Research. 2010 Volume 316, Issue 16 2630-2643 |
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Obesity, the Economic Meltdown, and the Gut Feeling for the Foods We Choose to Eat
- (Review Article)
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| Laugero, K.D. 2010. Obesity, the Economic Meltdown, and the Gut Feeling for the Foods We Choose to Eat. Clinical Nutrition Insight. |
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Trans fatty acids adversely affect blood lipids but not intra-abdominal and liver fat deposition - a randomized trial in overweight postmenopausal women
- (Peer Reviewed Journal)
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| Bendsen, N.T., Chabanova, E., Thomsen, H.S., Larsen, T.M., Newman, J.W., Stender, S., Dyerberg, J., Haugaard, S.B., Astrup, A. 2010. Trans fatty acids adversely affect blood lipids but not intra-abdominal and liver fat deposition - a randomized trial in overweight postmenopausal women. Nutrition and Diabetes. 1:e4; 10.1038. |
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Molecular Characterization of the Tumor Suppressor Candidate 5 Gene: Regulation by PPARg and Identification of TUSC5 Coding Variants in Lean and Obese Humans
- (Peer Reviewed Journal)
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| Knotts, T.A., Lee, H., Kim, J., Oort, P.J., Mcpherson, R., Dent, R., Tachibana, K., Doi, T., Yu, S., Reddy, J.K., Uno, K., Katagiri, H., Pasarica, M., Smith, S.R., Sears, D.S., Grino, M., Adams, S.H. 2009. Molecular Characterization of the Tumor Suppressor Candidate 5 Gene: Regulation by PPARg and Identification of TUSC5 Coding Variants in Lean and Obese Humans. Trade Journal Publication. PPAR Research Vol. Article ID 867678. 1-13, 2009. |
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Davalintide (AC2307), a Novel Amylin Mimetic Peptide: Enhanced Pharmacological Properties over Native Amylin to Reduce Food Intake and Body Weight
- (Peer Reviewed Journal)
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| Mack, C.M., Soares, C.J., Wilson, J.K., Athanacio, B.A., Turek, V., Trevaskis, J., Roth, J., Smith, P.A., Gedulin, B., Jodka, C.M., Roland, B.L., Adams, S.H., Lwin, A., Herich, J., Laugero, K.D., Vu, C., Pittner, R., Paterniti, J.R., Hanley, M., Ghosh, S., Parkes, D.G. 2009. Davalintide (AC2307), a Novel Amylin Mimetic Peptide: Enhanced Pharmacological Properties over Native Amylin to Reduce Food Intake and Body Weight. International Journal of Obesity. 34, 385-395, 2010. |
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Impact of circulating esterified eicosanoids and other oxylipins on endothelial function
- (Peer Reviewed Journal)
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| Shearer, G., Newman, J.W. 2009. Impact of circulating esterified eicosanoids and other oxylipins on endothelial function. Current Atherosclerosis Reports. Vol. 11:403-410. |
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Costs of pair-bonding and paternal care in male prairie voles (Microtus ochrogaster)
- (Peer Reviewed Journal)
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| Campbell, J.C., Laugero, K.D., Van Westerhuyzen, J.A., Hostetler, C.M., Cohen, J.D., Bales, K.L. 2009. Energetic costs of pair bonding and parental care in male prairie voles (Microtus ochrogaster). Physiology and Behavior. 98:367-373. |
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In polycystic ovary syndrome, adrenal steroids are regulated differently in the morning versus in response to nutrient intake
- (Peer Reviewed Journal)
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| Gurusinghe, D., Gill, S., Almario, R.U., Lee, J., Horn, W.F., Keim, N.L., Kim, K., Kasim-Karakas, S.E. 2009. In polycystic ovary syndrome, adrenal steroids are regulated differently in the morning versus in response to nutrient intake. Fertility and Sterility, 93(4):1192-1193, 2009. |
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Neuromedin and FN-38 Peptides for Treating Psychiatric Diseases
- (Other)
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| Laugero, K.D., Hanley, M.R., Parkes, D.G., Mcgonicle, P. 2010. Neuromedin and FN-38 Peptides for Treating Psychiatric Diseases. Patent Application. |
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