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United States Department of Agriculture

Agricultural Research Service

Research Project: STUDY OF INFLUENZA AND NEWCASTLE DISEASE VIRUSES CIRCULATING IN ASIA
2009 Annual Report


1a.Objectives (from AD-416)
The objective of this cooperative reearch project is to jointly study avian influenza viruses and paramyxoviruses (Newcastle disease) of poultry and wild birds that potentially can cross between birds and humans.


1b.Approach (from AD-416)
The tasks to be performed will include collection and analysis of field samples (cloacal/tracheal swabs, sera and organ samples) obtained from apparently healthy and diseased animals. Viruses will be isolated in cell cultures and embryonating chicken eggs. Antigenic and serological studies as well as molecular-epidemiological evaluation of newly isolated influenza and Newcastle disease virus strains will be done. Genomic analysis of influenza and Newcastle disease viruses isolates will include sequencing (full length or partial) of surface glycoproteins and internal genes and phylogenetic studies.


3.Progress Report

The project is related to objective 4 of the in-house project: Use molecular epidemiologic techniques and viral genomics to understand virus transmission and spread of avian influenza outbreaks in poultry and wild birds.

Some strains of avian influenza virus have been zoonotic agents necessitating joint research between veterinary medicine and human health to solve the problems including the H5N1 high pathogenicity avian influenza (HPAI) virus. The objective of this cooperative research project is to jointly study avian influenza viruses and paramyxoviruses (Newcastle disease) of poultry and wild birds that potential can cross between birds and humans. During 2009, two face-to-face planning sessions were held between ARS and the Cooperator during international scientific conferences Bangkok, Thailand and Athens, Georgia, U.S.A. Animal pathogenesis studies were planned for the cooperator laboratory and virus isolate exchanges were initiated.

Monitoring: The Principal Investigator had regular email and telephone conversations with the cooperator on research progress. Two face-to-face meetings occurred in 2009.


Last Modified: 10/23/2014
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