AVIAN GENOMIC AND IMMUNOLOGIC APPROACHES FOR CONTROLLING MUCOSAL PATHOGENS
Project Number: 1265-32000-086-00
Start Date: Apr 14, 2008
End Date: Oct 12, 2011
* Identify host nucleic acid and protein markers and functional genetic variations associated with disease susceptibility and resistance to mucosal pathogens of economic importance.
* Discover effective immune interventions strategies to prevent and control mucosal pathogens of poultry.
* Determine the host-pathogen interactions that result in immune evasion or protective immunity to avian mucosal pathogens.
High throughput genomic approaches will be interfaced with disease modeling studies to decipher genetic and biological determinants of disease susceptibility. This approach will lead to the discovery of innovative tools to prevent and control avian mucosal pathogens such as avian coccidiosis, avian influenza, infectious bronchitis, and other important mucosal pathogens of poultry. BSL-1 Recertified 4/15/11.