2009 Annual Report 1a.Objectives (from AD-416) To evaluate the adjuvant effects of Seppic's immunomodulators in poultry immune system. 1b.Approach (from AD-416) Broiler chickens will be treated with Seppic's immunomodulators and the effects on avian immune response to mucosal pathogens will be evaluated using established disease parameters and various immunological assays. 3.Progress Report Using novel immunoadjuvant formulations to elicit anti-viral, cell-mediated immunity, ARS scientists demonstrated the immunogenicity of the company’s proprietary adjuvant formulation using an in vivo disease challenge model with avian influenza.