2008 Annual Report 1a.Objectives (from AD-416) Evaluate the immunomodulatory effect of Pfizer's proprietary adjuvants in a poultry disease model. 1b.Approach (from AD-416) Investigate the efficacy of Pfizer's new adjuvant in formulation in Eimeria. 3.Progress Report This trust was established to develop methods for delivering recombinant poultry vaccines to chickens. Using novel immunomodulators, various delivery methods to activate local immunity against poultry pathogens are to be investigated. ARS provides expertise in immunology and vaccine delivery technology. This trust agreement is monitored by monthly teleconference and written progress reports.