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United States Department of Agriculture

Agricultural Research Service

Research Project: GENETIC AND BIOLOGICAL DETERMINANTS OF RESPIRATORY DISEASE SUSCEPTIBILITY Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)

Development and characterization of two porcine monocyte-derived macrophage cell lines - (Peer Reviewed Journal)
Chitko McKown, C.G., Chapes, S.K., Miller, L.C., Riggs, P.K., Ortega, M.T., Green, B.T., McKown, R.D. 2013. Development and characterization of two porcine monocyte-derived macrophage cell lines. Results in Immunology. 3:26-31.
Genome wide analysis of the world's sheep breeds reveals high levels of historic mixture and strong recent selection     Reprint Icon - (Peer Reviewed Journal)
Kijas, J.W., Lenstra, J.A., Porto Neto, L., Mcculloch, R., Whan, V., Gietzen, K., Paiva, S., Gill, C., Barendse, W., Ciani, E., Raadsma, H., Mcewan, J., Dalrymple, B., Heaton, M.P., et al. 2012. Genome wide analysis of the world's sheep breeds reveals high levels of historic mixture and strong recent selection. PLoS Biology. 10(2): e1001258. DOI:10.1371/journal.pbio.1001258.
Reduced lentivirus susceptibility in sheep with TMEM154 mutations - (Peer Reviewed Journal)
Heaton, M.P., Clawson, M.L., Chitko-Mckown, C.G., Leymaster, K.A., Smith, T.P.L., Harhay, G.P., White, S.N., Herrmann-Hoesing, L.M., Mousel, M.R., Lewis, G.S., Kalbfleisch, T.S., Keen, J.E., Laegreid, W.W. 2012. Reduced lentivirus susceptibility in sheep with TMEM154 mutations. PLoS Genetics. 8(1): e1002467. DOI: 10.1371/journal.pgen.1002467.
Innate immune responses of porcine macrophage cell line (Cdelts2+) to virus-associated virulence determinants - (Abstract Only)
Joseph, J., Chitko-Mckown, C.G., Kaushik, R.S. 2011. Innate immune responses of porcine macrophage cell line (Cdelts2+) to virus-associated virulence determinants [abstract]. Prodeedings of the 71st Annual Meeting of the North Central Branch of the American Society of Microbiology, October 7-8, 2011, Des Moines, Iowa. Page 118. Abstract #34.
A case report describing detection of Rhodoturola minuta fungemia in an ewe lamb - (Abstract Only)
Chitko Mckown, C.G., Leymaster, K.A., Heaton, M.P., Griffin, D.D., Veatch, J.K., Jones, S.A., Clawson, M.L. 2011. A case report describing detection of Rhodoturola minuta fungemia in an ewe lamb [Abstract]. Proceeding of the 2011 Conference of Research Workers in Animal Diseases, December 4-6, 2011, Chicago, Illinois. p. 95.
Discovery of a lentivirus susceptibility gene in sheep - (Abstract Only)
Heaton, M.P. 2011. Discovery of a lentivirus susceptibility gene in sheep. Queenstown Molecular Biology 2011 Meeting Abstracts.
Evolution of Shiga toxin-producing Escherichia coli O157: eight major lineages of human and cattle origin strain signature genotypes - (Abstract Only)
Clawson, M.L., Bono, J.L. 2011. Evolution of Shiga toxin-producing Escherichia coli O157: eight major lineages of human and cattle origin strain signature genotypes [abstract]. Proceedings of the BIT's 1st Annual World Congress of Microbes - 2011, July 30 - August 1, 2011, Beijing, China. p. 195.
Biosurveillance at the United States Meat Animal Research Center - (Abstract Only)
Harhay, G.P., Harhay, D.M., Chitko Mckown, C.G., Smith, T.P. 2011. Biosurveillance at the United States Meat Animal Research Center [abstract]. Global Biosurveillance: Enabling Science and Technology 2nd Biothreat Nonproliferation Conference. Abstract No. 12.
An atlas of bovine gene expression reveals novel distinctive tissue characteristics and evidence for improving genome annotation - (Peer Reviewed Journal)
Harhay, G.P., Smith, T.P.L., Alexander, L.J., Haudenschild, C.D., Keele, J.W., Matukumalli, L.K., Schroeder, S.G., Van Tassell, C.P., Gresham, C.R., Bridges, S.M., Burgess, S.C., Sonstegard, T.S. 2010. An atlas of bovine gene expression reveals novel distinctive tissue characteristics and evidence for improving genome annotation. Genome Biology [online serial]. 11:R102.
Survival of Mycobacterium avium subsp. paratuberculosis in bovine monocyte-derived macrophages - (Abstract Only)
McVey, D.S., Chitko-Mckown, C.G., Kuszak, J.A., Barletta, R.G. 2010. Survival of Mycobacterium avium subsp. paratuberculosis in bovine monocyte-derived macrophages [abstract]. Annual Conference of Research Workers in Animal Diseases. Abstract No. 113 [on-line].
Characterization of two porcine macrophage cell lines for the expression of pathogen-recognition receptors, defensins, cytokines, chemokines, and surface sialic acid - (Abstract Only)
Joseph, J., Sreenivasan, C., Chitko Mckown, C.G., Kaushik, R.S. 2010. Characterization of two porcine macrophage cell lines for the expression of pathogen-recognition receptors, defensins, cytokines, chemokines, and surface sialic acid [abstract]. American Society for Microbiology 70th Annual Meeting of the North Central Branch. Poster No. P-10.
Ovine Reference Materials and Assays for Prion Genetic Testing     Reprint Icon - (Peer Reviewed Journal)
Heaton, M.P., Leymaster, K.A., Kalbfleisch, T.S., Freking, B.A., Smith, T.P., Clawson, M.L., Laegreid, W.W. 2010. Ovine Reference Materials and Assays for Prion Genetic Testing. BioMed Central (BMC) Veterinary Research [serial online]. 6:23. Available: http://www.biomedcentral.com/1746-6148/6/23.
A 2cM Genome-Wide Scan of European Holstein Cattle Affected by Classical BSE     Reprint Icon - (Peer Reviewed Journal)
Murdoch, B.M., Clawson, M.L., Laegreid, W.W., Stothard, P., Settles, M., McKay, S., Prasad, A., Wang, Z., Moore, S.S., Williams, J.L. 2010. A 2cM Genome-Wide Scan of European Holstein Cattle Affected by Classical BSE. BioMed Central (BMC) Genetics [serial online]. 11:20. Available: http://www.biomedcentral.com/1471-2156/11/20.
A Digital Gene Expression-Based Bovine Gene Atlas Evaluating 92 Adult, Juvenile and Fetal Cattle Tissues - (Abstract Only)
Harhay, G.P., Alexander, L.J., Smith, T.P.L., Matukumalli, L.K., Schroeder, S.G., Sonstegard, T.S. 2010. A Digital Gene Expression-Based Bovine Gene Atlas Evaluating 92 Adult, Juvenile and Fetal Cattle Tissues [abstract]. In: Proceedings of the Advances in Genome Biology & Technology Conference, February 24-27, 2010, Marco Island, Florida. p. 67.
Development of Fibroblast Cell Lines From the Cow Used to Sequence the Bovine Genome     Reprint Icon - (Peer Reviewed Journal)
Chitko Mckown, C.G., Macneil, M.D. 2010. Development of Fibroblast Cell Lines From the Cow Used to Sequence the Bovine Genome. Animal Genetics. 41(4):445.
Ovine Reference Materials and Assays for Prion Genetic Testing - (Abstract Only)
Heaton, M.P., Leymaster, K.A., Kalbfleisch, T.S., Freking, B.A., Smith, T.P., Clawson, M.L., Laegreid, W.W. 2009. Ovine Reference Materials and Assays for Prion Genetic Testing [abstract]. Plant and Animal Genomes XVIII Conference. Abstract No. P577. Available: http://www.intl-pag.org/18/abstracts/
Discovery, Validation and Characterization of 1039 Cattle Single Nucleotide Polymorphisms     Reprint Icon - (Peer Reviewed Journal)
Donthu, R., Larkin, D.M., Heaton, M.P., Lewin, H.A. 2010. Discovery, Validation and Characterization of 1039 Cattle Single Nucleotide Polymorphisms. Animal Genetics. 41(4):421-423.
Associations Between Haemonchus contortus Infection in Lambs and Blood Traits - (Abstract Only)
Chitko-McKown, C.G., Leymaster, K.A. 2009. Associations Between Haemonchus contortus Infection in Lambs and Blood Traits. Proceeding of the 90th Conference of Research Workers in Animal Diseases, December 5-8, 2009, Chicago, Illinois. Poster No. 105P. p. 112.
Resolving the Evolution of Extant and Extinct Ruminants With High-Throughput Phylogenomics     Reprint Icon - (Peer Reviewed Journal)
Decker, J.E., Pires, J.C., Conant, G.C., McKay, S.D., Heaton, M.P., Chen, K., Cooper, A., Vilkki, J., Seabury, C.M., Caetano, A.R., Johnson, G.S., Brenneman, R.A., Hanotte, O., Eggert, L.S., Wiener, P., Kim, J.J., Kim, K.S., Sonstegard, T.S., Van Tassell, C.P., Neibergs, H.L., McEwan, J.C., Brauning, R., Coutinho, L.L., Babar, M.E., Wilson, G.A., McClure, M.C., Rolf, M.M., Kim, J., Schnabel, R.D., Taylor, J.F. 2009. Resolving the Evolution of Extant and Extinct Ruminants With High-Throughput Phylogenomics. Proceedings of the National Academy of Sciences. 106(44):18644-18649.
Frequent Missense and Insertion/Deletion Polymorphisms in the Ovine Shadoo Gene Parallel Species-Specific Variation in PrP     Reprint Icon - (Peer Reviewed Journal)
Daude, N., Wohlgemuth, S., Rogaeva, E., Farid, A.H., Heaton, M.P., Westaway, D. 2009. Frequent Missense and Insertion/Deletion Polymorphisms in the Ovine Shadoo Gene Parallel Species-Specific Variation in PrP. PLoS One [serial online]. 4(8):e6538.
A Genome Wide Survey of SNP Variation Reveals the Genetic Structure of Sheep Breeds     Reprint Icon - (Peer Reviewed Journal)
Kijas, J.W., Townley, D., Dalrymple, B.P., Heaton, M.P., Maddox, J.F., McGrath, A., Wilson, P., Ingersoll, R.G., McCulloch, R., McWilliam, S., Tang, D., McEwan, J., Cockett, N., Oddy, V.H., Nicholas, F.W., Raadsma, H. 2009. A Genome Wide Survey of SNP Variation Reveals the Genetic Structure of Sheep Breeds. PLoS One [serial online]. 4(3):e4668. Available: http://www.plosone.org.
Association of a bovine prion gene haplotype with atypical BSE - (Abstract Only)
Clawson, M.L. 2009. Association of a bovine prion gene haplotype with atypical BSE [abstract]. Plant and Animal Genomes XVII Conference. Abstract No. W091. Available: http://www.intl-pag.org/17/abstracts/
A web-based genome browser for 'SNP-aware' assay design - (Abstract Only)
Morris, J.P., Heaton, M.P., Kalbfleisch, T.S. 2009. A web-based genome browser for 'SNP-aware' assay design [abstract]. Plant and Animal Genomes XVII Conference. Abstract No. CP843. Available: http://www.intl-pag.org/17/abstracts/
Effects of PRRSV infection on TLR-dependent induction of NOS - (Abstract Only)
Chitko McKown, C.G., Miller, L.C., Lager, K.M., Kehrli Jr, M.E. 2008. Effects of PRRSV infection on TLR-dependent induction of NOS (abstract). Proceedings of the 89th Conference of Research Workers in Animal Health. Poster No. 104P. p. 122.
Characterization of the porcine monocyte-derived cell lines Cdelta2- and Cdelta2+ - (Abstract Only)
Chitko Mckown, C.G., Chapes, S.K., Miller, L.C., Green, B.T. 2008. Characterization of the porcine monocyte-derived cell lines Cdelta2+ and Cdelta2+ [abstract]. Society for Leukocyte Biology. Poster No. 45.
Scrapie resistance in ARQ sheep - (Peer Reviewed Journal)
Laegreid, W.W., Clawson, M.L., Heaton, M.P., Green, B.T., Orourke, K.I., Knowles Jr, D.P. 2008. Scrapie resistance in ARQ sheep. Journal of Virology. 82(20):10318-10320. Available: DOI:10.1128/JVI.00710-08.
A sequencing strategy for identifying variation throughout the prion gene of BSE-affected cattle - (Peer Reviewed Journal)
Clawson, M.L., Heaton, M.P., Keele, J.W., Smith, T.P., Harhay, G.P., Richt, J., Laegreid, W.W. 2008. A sequencing strategy for identifying variation throughout the prion gene of BSE-affected cattle. BMC Research Notes [journal online]. 1:32. Available: http://www.biomedcentral.com/1756-0500/1/32.
Development of cell lines from the sheep used to construct the CHORI-243 ovine BAC library - (Peer Reviewed Journal)
Chitko Mckown, C.G., Leonard, J.C., Moscatello, D., Miller, L.C., Freking, B.A. 2008. Development of cell lines from the sheep used to construct the CHORI-243 ovine BAC library. Animal Biotechnology. 19(2):84-88.
Prevalence of the prion gene E211K variant in U.S. cattle - (Abstract Only)
Heaton, M.P., Keele, J.W., Harhay, G.P., Richt, J., Koohmaraie, M., Wheeler, T.L., Shackelford, S.D., Casas, E., King, D.A., Sonstegard, T.S., Van Tassell, C.P., Neibergs, H.L., Chase, C.C., Kalbfleisch, T.S., Smith, T.P., Clawson, M.L., Laegreid, W.W. 2008. Prevalence of the prion gene E211K variant in U.S. cattle (abstract). Plant and Animal Genome XVI Conference. Poster No. P538.
Scrapie resistance in ARQ sheep - (Abstract Only)
Laegreid, W.W., Clawson, M.L., Heaton, M.P., Green, B.T., Orourke, K.I., Knowles Jr, D.P. 2008. Scrapie resistance in ARQ sheep (abstract). Plant and Animal Genome XVI Conference. Poster No. P550.
Localization of thioredoxin in Fasciola hepatica - (Abstract Only)
Mckown, R.D., Chitko Mckown, C.G., Richardson, C.D., Wojcieszyn, J.W., Craig, T.M., Rice-Ficht, A.C. 2007. Localization of thioredoxin in Fasciola hepatica [abstract]. Proceedings of the 88th Conference of Research Workers in Animal Diseases. Presentation No. 124.
The role of CD163 for PRRSV infection - (Abstract Only)
Song, C., Chang, K., Chitko Mckown, C.G., Bienzle, D., Zuckermann, F.A., Yoo, D. 2007. The role of CD163 for PRRSV infection [abstract]. Proceedings of the 88th Conference of Research Workers in Animal Health. Poster No. 131P.
Last Modified: 9/20/2014
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