2008 Annual Report
One problem with developing safe strategies for nematode control is that the number of nematode molecular targets vulnerable to being exploited by control strategies is very small. Therefore, ARS scientists at Beltsville, Maryland have examined several such targets and have determined that members of a group of naturally occurring small molecules called neuropeptides, which control behaviors in the soybean cyst nematode and root-knot nematodes, are metabolized differently depending upon the type of specific neuropeptide and the species of nematode. Because these peptide molecules regulate the critical processes of movement, hatching and feeding, this discovery is important because it is the first indication that nematodes will not survive when the supply or action of these peptide molecules is altered. Therefore, this information is expected to impact scientists who are developing highly specific inhibitors and new strategies for controlling plant-parasitic nematodes for the eventual benefit of growers. This research directly addresses Component 2 (Biology, Ecology, Epidemiology, and Spread of Plant Pathogens and Their Relationships with Hosts and Vectors) of National Program 303 (Plant Diseases); specifically, Problem Statement 2A (Pathogen Biology, Virulence Determinants, and Genetics of the Pathogen.)
5.Significant Activities that Support Special Target Populations
Masler, E.P. 2008. Invertebrate Neuropeptides. In: Meyers, R.A., editor. Neurobiology. From Molecular Basis to Disease. Vol. 1. Weinheim: Wiley-VCH Verlag. p. 257-271.
Masler, E.P. 2007. Responses of Heterodera glycines and Meloidogyne incognita to exogenously applied neuromodulators. Journal of Helminthology. 81:421-427.
Masler, E.P. 2007. Characterization of aminopeptidase in the free-living nematode Panagrellus redivivus: subcellular distribution and possible role in neuropeptide metabolism. Journal of Nematology. 39(2):153-160.
Pridannikov, M.V., Petelina, G.G., Palchuk, M.V., Masler, E.P., Dzhavakhiya, V.G. 2007. Influence of components of Globodera rostochiensis cysts on the in vitro hatch of second-stage juveniles. Nematology. 9(6):837-844.
Masler, E.P., Donald, P.A., Sardanelli, S.S. 2008. Stability of Heterodera glycines (Tylenchida: Heteroderidae) juvenile hatching from eggs obtained from different sources of soybean, Glycine max. Nematology. 10(2):271-278.
Masler, E.P., Zasada, I.A., Sardanelli, S. 2008. Hatching behavior in Heterodera glycines in response to low temperature. Comparative Parasitology. 75(1):76-81.