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United States Department of Agriculture

Agricultural Research Service

Research Project: IMMUNOLOGIC AND PHARMACOLOGICAL INTERVENTIONS OF VECTOR-BORNE BABESIOSIS

Location: Animal Diseases Research

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)

Characterization of acyl carrier protein and LytB in Babesia bovis apicoplast - (Peer Reviewed Journal)
Caballero, M.C., Pedroni, M.J., Palmer, G.H., Suarez, C.E., Davitt, C., Lau, A.T. 2012. Characterization of acyl carrier protein and LytB in Babesia bovis apicoplast. Molecular and Biochemical Parasitology. (2):125-33.
Protective effects of passively transferred merozoite-specific antibodies against Theileria equi in horses with severe combined immunodeficiency     Reprint Icon - (Peer Reviewed Journal)
Mealey, R.H., Kappmeyer, L.S., Ueti, M.W., Wagner, B., Knowles Jr, D.P. 2011. Protective effects of passively transferred merozoite-specific antibodies against Theileria equi in horses with severe combined immunodeficiency. Clinical and Vaccine Immunology. 19(1):100-4.
Expression and strain variation of the novel “Small Open Reading Frame” 3 (smorf) multigene family in Babesia bovis - (Peer Reviewed Journal)
Ferreri, L.M., Brayton, K.A., Sondergoth, K.S., Lau, A.T., Suarez, C.E., Mcelwain, T.F. 2012. Expression and strain variation of the novel “Small Open Reading Frame” 3 (smorf) multigene family in Babesia bovis. International Journal for Parasitology. 42(2):131-8.
Equine Piroplasmosis Associated with Amblyomma cajennense Ticks, Texas, USA     Reprint Icon - (Peer Reviewed Journal)
Scoles, G.A., Hutcheson, H.J., Schlater, J.L., Hennager, S.G., Pelzel, A.M., Knowles Jr, D.P. 2011. Equine Piroplasmosis Associated with Amblyomma cajennense Ticks, Texas, USA. Emerging Infectious Diseases. 17(10)1903-1905.
A novel neutralization sensitive and subdominant RAP-1-related antigen (RRA) is expressed by babesia bovis merozoites - (Peer Reviewed Journal)
Suarez, C.E., Laughery, J., Bastos, R., Johnson, W.C., Norimine, J., Asenzo, G., Brown, W.C., Florin-Christensen, M., Goff, W.L. 2011. A novel neutralization sensitive and subdominant RAP-1-related antigen (RRA) is expressed by Babesia bovis merozoites. Parasitology. 10.1017/S0031182011000321.
Emerging perspectives in the research of bovine Babesiosis and Anaplasmosis - (Peer Reviewed Journal)
Suarez, C.E., Noh, S.M. 2011. Emerging perspectives in the research of bovine Babesiosis and Anaplasmosis. Veterinary Parasitology. 180(102):109-25.
Bovipain-2, the falcipain-2 ortholog, is expressed in intraerythrocytic stages of the tick-transmitted hemoparasite Babesia bovis - (Peer Reviewed Journal)
Mesplet, M., Echaide, I., Dominguez, M., Mosqueda, J.J., Suarez, C.E., Schnittger, L., Florin-Christensen, M. 2010. Bovipain-2, the falcipain-2 ortholog, is expressed in intraerythrocytic stages of the tick-transmitted hemoparasite Babesia bovis. Parasites & Vectors. 10.1186/1756-3305-3-113.
Babesia bovis expresses Bbo-6cys-E, a member of a novel gene family that is homologous to the 6-cys family of Plasmodium - (Peer Reviewed Journal)
(19-Sep-10)
The novel protein BboRhop68 is expressed by intraerytrhocytic stages of Babesia bovis - (Peer Reviewed Journal)
(26-Jul-10)
Dynamics of bovine spleen cell populations during the response to acute Babesia bovis infection: an immunohistological study     Reprint Icon - (Peer Reviewed Journal)
Schneider, D.A., Yan, H., Bastos, R.G., Johnson, W.C., Gavin, P.R., Allen, A.J., Barrington, G.M., Hoesing, L.M., Knowles Jr, D.P., Goff, W.L. 2010. Dynamics of bovine spleen cell populations during the response to acute Babesia bovis infection: an immunohistological study. Parasite Immunology. Available: onlinelibrary.wiley.com/doi/10.1111/j.1365-3024.2010.01249.x/pdf.
Understanding Piroplasmosis - (Review Article)
Knowles Jr, D.P. 2010. Understanding Piroplasmosis. Equine Disease Quarterly. 19(3):4-5.
Babesia bovis expresses a neutralization-sensitive antigen that contains a microneme adhesive repeat (MAR) domain     Reprint Icon - (Peer Reviewed Journal)
Silva, M.G., Ueti, M., Norimine, J., Florin-Christensen, M., Bastos, R., Goff, W.L., Brown, W.C., Oliva, A., Suarez, C.E. 2010. Babesia bovis expresses a neutralization-sensitive antigen that contains a microneme adhesive repeat (MAR) domain. Parasitology International. Available: doi:10.1016/j.parint.2010.03.004
Silencing of a putative immunophilin gene in the cattle tick Rhipicephalus (Boophilus) microplus increases the infection rate of Babesia bovis in larval progeny     Reprint Icon - (Peer Reviewed Journal)
Bastos, R., Ueti, M.W., Guerrero, F., Knowles Jr, D.P., Scoles, G.A. 2009. Silencing of a putative immunophilin gene in the cattle tick Rhipicephalus (Boophilus) microplus increases the infection rate of Babesia bovis in larval progeny. BioMed Central (BMC) Vectors and Parasites. 2(1):57.
Babesia bovis: a comprehensive phylogenetic analysis of plastid-encoded genes supports green algal origin of apicoplasts - (Peer Reviewed Journal)
Lau, A.O., Mcelwain, T.F., Brayton, K.A., Knowles Jr, D.P., Roalson, E.H. 2009. Babesia bovis: a comprehensive phylogenetic analysis of plastid-encoded genes supports green algal origin of apicoplasts. Experimental Parasitology. 123(3):236-243.
First survey for Babesia bovis and Babesia bigemina infection in cattle from Central and Southern regions of Portugal using serological and DNA detection methods - (Peer Reviewed Journal)
Silva, M., Henriques, G., Sanchez, C., Marques, P.X., Suarez, C.E., Oliva, A. 2009. First survey for Babesia bovis and Babesia bigemina infection in cattle from Central and Southern regions of Portugal using serological and DNA detection methods. Veterinary Parasitology. 166(1-2):66-72.
Imidocarb dipropionate clears persistent Babesia caballi infection with elimination of transmission potential     Reprint Icon - (Peer Reviewed Journal)
Schwint, O.N., Ueti, M.W., Palmer, G.H., Kappmeyer, L.S., Hines, M.T., Cordes, R.T., Knowles Jr, D.P., Scoles, G.A. 2009. Imidocarb dipropionate clears persistent Babesia caballi infection with elimination of transmission potential. Antimicrobial Agents and Chemotherapy. 53(10):4327-4332.
Prevalence of equine Piroplasmosis and its association with tick infestation in the State of Sao Paulo, Brazil - (Peer Reviewed Journal)
Kerber, C.E., Labruna, M.B., Ferreira, F., De Waal, D.T., Knowles Jr, D.P., Gennari, S.M. 2009. Prevalence of equine Piroplasmosis and its association with tick infestation in the State of Sao Paulo, Brazil. Brazilian Journal of Veterinary Parasitology. 18(4):1-8.
Babesia bovis: Transcriptional analysis of rRNA gene unit expression     Reprint Icon - (Peer Reviewed Journal)
Laughery, J.M., Lau, A.O., White, S.N., Howell, J.M., Suarez, C.E. 2009. Babesia bovis: Transcriptional analysis of rRNA gene unit expression. Experimental Parasitology. 123(1):45-50.
Quantification of Theileria parva in Rhipicephalus appendiculatus (Acari: Ixodidae) Confirms Differences in Infection Between Selected Tick Strains     Reprint Icon - (Peer Reviewed Journal)
Odongo, D., Ueti, M.W., Mwaura, S., Knowles Jr, D.P., Bishop, R., Scoles, G.A. 2009. Quantification of Theileria parva in Rhipicephalus appendiculatus (Acari: Ixodidae) Confirms Differences in Infection Between Selected Tick Strains. Journal of Medical Entomology. 46(4):888-894.
Development of a tandem repeat-based multilocus typing system distinguishing Babesia bovis geographic isolates     Reprint Icon - (Peer Reviewed Journal)
Perez-Llaneza, A., Caballero, M., Baravalle, E., Mesplet, M., Mosqueda, J., Suarez, C.E., Echaide, I., Katzer, F., Pacheco, G.M., Florin-Christensen, M., Schnittger, L. 2010. Development of a tandem repeat-based multilocus typing system distinguishing Babesia bovis geographic isolates. Veterinary Parasitology. 167(2-4):196-204.
In silico predicted conserved B-cell epitopes in the Merozoite Surface Antigen -2 family of B. bovis are neutralization-sensitive     Reprint Icon - (Peer Reviewed Journal)
Dominguez, M., Echaide, I., Torioni De Echaide, S., Mosqueda, J., Cetra, B., Suarez, C.E., Florin-Christensen, M. 2010. In silico predicted conserved B-cell epitopes in the Merozoite Surface Antigen -2 family of B. bovis are neutralization-sensitive. Veterinary Parasitology. 167(2-4):216-226.
Transfection systems for Babesia bovis: a review of methods for the transient and stable expression of exogenous genes     Reprint Icon - (Peer Reviewed Journal)
Suarez, C.E., Mcelwain, T.F. 2010. Transfection systems for Babesia bovis: a review of methods for the transient and stable expression of exogenous genes. Veterinary Parasitology. 167(2-4):205-215.
An impedance spectroscopy method for the detection and evaluation of Babesia bovis antibodies in cattle     Reprint Icon - (Peer Reviewed Journal)
Silva, M., Helali, S., Esseghaierb, C., Suarez, C.E., Oliva, A., Abdelghani, A. 2008. An impedance spectroscopy method for the detection and evaluation of Babesia bovis antibodies in cattle. Sensors and Actuators B: Chemical. 135:206-213.
Stable expression of a GFP-BSD fusion protein in Babesia bovis merozoites     Reprint Icon - (Peer Reviewed Journal)
Suarez, C.E., Mcelwain, T. 2009. Stable expression of a GFP-BSD fusion protein in Babesia bovis merozoites. International Journal for Parasitology. 39(3):289-297.
Validation of a Competitive Enzyme-Linked Immunosorbent Assay for Detection of Babesia bigemina Antibodies in Cattle     Reprint Icon - (Peer Reviewed Journal)
Goff, W.L., Johnson, W.C., Molloy, J.B., Jorgensen, W.K., Waldron, S.J., Figueroa, J.V., Matthee, O., Adams, D.S., Mcguire, T.C., Pino, I., Mosqueda, J., Palmer, G.H., Suarez, C.E., Knowles Jr, D.P., Mcelwain, T.F. 2008. Validation of a Competitive Enzyme-Linked Immunosorbent Assay for Detection of Babesia bigemina Antibodies in Cattle. Clinical and Vaccine Immunology. 15(9):1316-1321.
Bovine NK cells acquire cytotoxic activity and produce IFN-gamma after stimulation by Mycobacterium bovis BCG- or Babesia bovis-exposed splenic dendritic cells - (Peer Reviewed Journal)
Bastos, R.G., Johnson, W.C., Mwangi, W., Brown, W.C., Goff, W.L. 2008. Bovine NK cells acquire cytotoxic activity and produce IFN-gamma after stimulation by Mycobacterium bovis BCG- or Babesia bovis-exposed splenic dendritic cells. Veterinary Immunology and Immunopathology. 124:302-312.
Bovine WC1- gamma delta T-cells incubated with IL-15 express the natural cytotoxicity receptor CD335 (NKp46) and produce IFN-gamma in response to exogenous IL-12 and IL-18 - (Peer Reviewed Journal)
Johnson, W.C., Bastos, R.G., Davis, W.C., Goff, W.L. 2008. Bovine WC1- gamma delta T-cells incubated with IL-15 express the natural cytotoxicity receptor CD335 (NKp46) and produce IFN-gamma in response to exogenous IL-12 and IL-18. Developmental and Comparative Immunology. 32:1002-1010.
Molecular Characterization of Babesia bovis Strains Using PCR Restriction Fragment Length Polymorphism Analysis of the msa2-a/b Genes     Reprint Icon - (Peer Reviewed Journal)
Wilcowsky, S., Farber, M., Gil, G., Echaide, I., Mosqueda, J., Alcaraz, E., Suarez, C.E., Florin-Christensen, M. 2008. Molecular Characterization of Babesia bovis strains using PCR restriction length polymorphism analysis of the msa2s/b genes. Annals of the New York Academy of Sciences. 1149:141-144.
Transient transfection of purified Babesia bovis merozoites - (Peer Reviewed Journal)
Suarez, C.E., Mcelwain, T.F. 2008. Transient transfection of purified Babesia bovis merozoites. Experimental Parasitology. 118(4):498-504.
Genome Sequence of Babesia bovis and Camparative Analysis of Apicomplexan Hemoprotozoa - (Peer Reviewed Journal)
Brayton, K., Lau, A.O., Herndon, D.R., Hannick, L., Kappmeyer, L.S., Berens, S.J., Bidwell, S.L., Brown, W.C., Crabtree, J., Fadrosh, D., Feldblum, T., Forberger, H.A., Haas, B.J., Howell, J.M., Khouri, H., Koo, H., Mann, D.J., Norimine, J., Paulsen, I.T., Radune, D., Ren, Q., Smith, R.K., Suarez, C.E., White, O., Wortman, J.R., Knowles Jr, D.P., Mcelwain, T.F., Nene, V.M. 2007. Genome Sequence of Babesia bovis and Camparative Analysis of Apicomplexan Hemoprotozoa. PLoS Pathogens. 3(10):1401-1413.
Persistently Infected Calves as Reservoirs for Acquisition and Transovarial Transmission of Babesia bovis by Rhipicephalus (Boophilus) microplus - (Peer Reviewed Journal)
Howell, J.M., Ueti, M.W., Palmer, G.H., Scoles, G.A., Knowles Jr, D.P. 2007. Persistently Infected Calves as Reservoirs for Acquisition and Transovarial Transmission of Babesia bovis by Rhipicephalus (Boophilus) microplus. Journal of Clinical Microbiology. 45(10):3155-3159
Evidence for a relationship between bovine erythrocyte lipid membrane peculiarities and immune pressure from ruminal ciliates     Reprint Icon - (Peer Reviewed Journal)
Gimenez, G., Florin-Christensen, M., Belaunzaran, M.L., Isola, E.L., Suarez, C.E., Florin-Christensen, J. 2007. Evidence for a relationship between bovine erythrocyte lipid membrane peculiarities and immune pressure from ruminal ciliates. Veterinary Immunology and Immunopathology. 119(3-4):171-179.
Optimizacion of Babesia bovis transfection methods - (Monograph)
Suarez, C.E., Laughery, J., Gonzalez, M.G., Mcelwain, T. 2007. Optimizacion of Babesia bovis transfection methods. Parassitologia. 49(Suppl. 1):67-70.
Search for Babesia bovis vaccine candidates - (Monograph)
Florin-Christensen, M., Schnittger, L., Dominguez, M., Mesplet, M., Rodriguez, A., Ferreri, L., Asenzo, G., Wilkowsky, S., Farber, M., Echaide, I., Suarez, C.E. 2007. Search for Babesia bovis vaccine candidates. Parassitologia. 49(Suppl. 1):9-12.
Taking advantage of the polymorphism of the MSA-2 family for Babesia bovis strain characterization - (Monograph)
Wilkowsky, S., Farber, M., Echaide, I., Mosqueda, J., Alcaraz, E., Suarez, C.E., Florin-Christensen, M. 2007. Taking advantage of the polymorphism of the MSA-2 family for Babesia bovis strain characterization. Parassitologia. 49(Suppl. 1):63-66.
Stable expression of a GFP-BSD fusion protein in transfected and blasticidin-selected B. bovis merozoites - (Abstract Only)
Suarez, C.E., Mcelwain, T.F. 2007. Stable expression of a GFP-BSD fusion protein in transfected and blasticidin-selected B. bovis merozoites. Molecular Parasitology Meeting XVIII, September 16-20, Woods Hole, MA.
Bovine Spongiform Encephalopathy - (Book / Chapter)
Knowles Jr, D.P. 2008. Bovine Spongiform Encephalopathy. In: Brown, C., Torres, A., editors. The United States Animal Health Association - Foreign Animal Diseases. Seventh Edition. Boca Raton, FL: Boca Publications Group, Inc. p. 185-188.
Last Modified: 8/30/2014
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