Publications (Clicking on the reprint icon will take you to the publication reprint.)

Methylation and in vivo expression of the surface-exposed Leptospira interrogans outer membrane protein OmpL32 - (Peer Reviewed Journal)

Eshghi, A., Pinne, M., Haake, D.A., Zuerner, R.L., Frank, A.T., Cameron, C.E. 2012. Methylation and in vivo expression of the surface-exposed Leptospira interrogans outer-membrane protein OmpL32. Microbiology. 158(Pt. 3):622-635.

Development of Chronic and Acute Golden Syrian Hamster Infection Models with Leptospira borgpetersenii serovar Hardjo - (Peer Reviewed Journal)

Zuerner, R.L., Alt, D.P., Palmer, M.V. 2011. Development of chronic and acute Golden Syrian Hamster infection models with Leptospira borgpetersenii serovar Hardjo. Veterinary Pathology. 49(2):403-411.

Diagnostic testing for Leptospirosis in California sea lions (Zalophus californianus) - (Abstract Only)

(15-Mar-11)

A Leptospira borgpetersenii Serovar Hardjo vaccine induces a Th1 response, activates NK cells, and reduces renal colonization - (Peer Reviewed Journal)

Zuerner, R.L., Alt, D.P., Palmer, M.V., Thacker, T.C., Olsen, S.C. 2011. A Leptospira borgpetersenii Serovar Hardjo vaccine induces a Th1 response, activates NK cells, and reduces renal colonization. Clinical and Vaccine Immunology. 18(4):684-691.

Transcriptional response of Leptospira interrogans to iron limitation and characterization of a PerR homolog - (Peer Reviewed Journal)

Lo, M., Murray, G., Khoo, C.A., Haake, D., Zuerner, R.L., Adler, B. 2010. Transcriptional response of Leptospira interrogans to iron limitation and characterization of a PerR homolog. Infection and Immunity. 78(11):4850-4859.

Global Proteome Analysis of Leptospira interrogans     - (Peer Reviewed Journal)

Eshghi, A.A., Cullen, Paul, Cowen, L., Zuerner, R.L., Cameron, C.E. 2009. Global Proteome Analysis of Leptospira interrogans. Journal of Proteome Research. 8(10):4564-4578.

Dissecting the Influences of Climate and Demography on the Dynamics of Leptospirosis in California Sea Lions - (Abstract Only)

Lloyd-Smith, J.O., Pepin, K., Greig, D., Melin, S., Laake, J., Lowry, M., Nutter, F., Zuerner, R.L., Delong, R.D., Gulland, F., Grenfell, B.T. 2009. Dissecting the Influences of Climate and Demography on the Dynamics of Leptospirosis in California Sea Lions [abstract]. Poster No. 6B.2.

Transcriptional Response of Leptospira interrogans to Different Iron Sources - (Abstract Only)

Lo, M., Ellis, K., Murray, G., Haake, D., Matsunaga, J., Zuerner, R.L., Adler, B. 2009. Transcriptional Response of Leptospira interrogans to Different Iron Sources [abstract].

Development of Hamster Models for Acute and Chronic Infections with Leptospira borgpetersenii serovar Hardjo - (Abstract Only)

Zuerner, R.L., Alt, D.P., Palmer, M.V. 2009. Development of Hamster Models for Acute and Chronic Infections with Leptospira borgpetersenii serovar Hardjo. Meeting Abstract.

Molecular Markers, MAT and Modeling: New Evidence for Leptospirosis Being Endemic in California Sea Lions, with Periodic Epizootics that Defy the Host-adapted Strain Paradigm - (Abstract Only)

Gulland, F., Greig, D., Lloyd-Smith, J., Zuerner, R.L. 2009. Molecular Markers, MAT and Modeling: New Evidence for Leptospirosis Being Endemic in California Sea Lions, with Periodic Epizootics that Defy the Host-adapted Strain Paradigm [abstract].

Bovine Immune Response to Papillomatous Digital Dermatitis (PDD)-associated Spirochetes is Skewed in Isolate Reactivity and Subclass Elicitation     - (Peer Reviewed Journal)

Elliott, M.K., Alt, D.P. 2009. Bovine Immune Response to Papillomatous Digital Dermatitis (PDD)-associated Spirochetes is Skewed in Isolate Reactivity and Subclass Elicitation. Veterinary Immunology and Immunopathology. 130(3-4):256-261.

Variable Nucleotide Tandem-Repeat Analysis Revealing a Unique Group of Leptospira interrogans Serovar Pomona Isolates Associated with California Sea Lions - (Peer Reviewed Journal)

Zuerner, R.L., Alt, D.P. 2009. Variable Nucleotide Tandem-Repeat Analysis Revealing a Unique Group of Leptospira interrogans Serovar Pomona Isolates Associated with California Sea Lions. Journal of Clinical Microbiology. 47(4):1202-1205.

Genus II. Leptonema Hovind-Hougen 1983, 439AL - (Book / Chapter)

Zuerner, R.L. 2011. Genus II. Leptonema Hovind-Hougen 1983, 439VP. In: Krieg, N., Staley, J., Brown, D., Hedlund, B., Paster, B., Ward, N., Wolfgang, L., Whitman, W., editors. Bergey's Manual of Systematic Bacteriology. 2nd edition. New York, Dordrecht, Heidelberg, London: Springer. p. 556-557.

Genus III. Turneriella Levett, Morey, Galloway, Steigerwalt, Ellis 2005, 1497AL - (Book / Chapter)

Zuerner, R.L. 2011. Genus III. Turneriella Levett, Morey, Galloway, Steigerwalt and Ellis 2005, 1499 VP. In: Krieg, N., Staley, J., Brown, D., Hedlund, B., Paster, B., Ward, N., Wolfgang, L., Whitman, W., editors. Bergey's Manual of Systematic Bacteriology. 2nd edition. New York, Dordrecht, Heidelberg, London: Springer. p. 558-560.

Genus I. Leptospira - (Book / Chapter)

Zuerner, R.L. 2011. Genus I. Leptospira Noguchi 1917, 755AL emend. Faine and Stallman 1982, 461. In: Krieg, N., Staley, J., Brown, D., Hedlund, B., Paster, B., Ward, N., Wolfgang, L., Whitman, W., editors. Bergey's Manual of Systematic Bacteriology. 2nd edition. New York, Dordrecht, Heidelberg, London: Springer. p. 546-555.

Family II. Leptospiraceae Hovind-Hougen 1979, 245AL - (Book / Chapter)

Zuerner, R.L. 2011. Family II. Leptospiraceae Hovind-Hougen 1979, 245AL. In: Krieg, N., Staley, J., Brown, D., Hedlund, B., Paster, B., Ward, N., Wolfgang, L., Whitman, W., editors. Bergey's Manual of Systematic Bacteriology. 2nd edition. New York, Dordrecht, Heidelberg, London: Springer. p. 556.

Geographical Dissemination of Leptospira interrogans serovar Pomona During Seasonal Migration of California Sea Lions - (Peer Reviewed Journal)

Zuerner, R.L., Cameron, C.E., Raverty, S., Robinson, J., Colegrove, K., Norman, S.A., Lambourn, D., Jeffries, S., Alt, D.P., Gulland, F. 2009. Geographical Dissemination of Leptospira interrogans serovar Pomona During Seasonal Migration of California Sea Lions. Veterinary Microbiology. 137(1-2):105-110.

Genetic Diversity of the Leptospiral Immunoglobulin-like (Lig) Genes in Pathogenic Leptospira spp. - (Peer Reviewed Journal)

Mcbride, A.J., Cerqueira, G.M., Suchard, M.A., Moreira, A.N., Zuerner, R.L., Reis, M.G., Haake, D.A., Ko, A.I., Dellagostin, O.A. 2009. Genetic Diversity of the Leptospiral Immunoglobulin-like (Lig) Genes in Pathogenic Leptospira spp.. Infection, Genetics and Evolution. 9(2):196-205.

Conservation of the S10-spc-alpha Locus within Otherwise Highly Pastic Genomes Provides Phylogenetic Insight into the Genus Leptospira     - (Peer Reviewed Journal)

Victoria, B., Ahmed, A., Zuerner, R.L., Ahmed, N., Bulach, D.M., Quinteiro, J., Hartskeerl, R.A. 2008. Conservation of the S10-spc-alpha Locus within Otherwise Highly Plastic Genomes Provides Phylogenetic Insight into the Genus Leptospira. PLoS One. 3(7):1-9. Available: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0002752.

Transcriptional Response of Leptospira interrogans to Different Iron Sources - (Abstract Only)

Lo, M., Ellis, K., Murray, G., Haake, D., Matsunaga, J., Zuerner, R.L., Adler, B. 2008. Transcriptional Response of Leptospira interrogans to Different Iron Sources [abstract]. GENOMES 2008: Functional Genomics of Microorganisms. Poster No. L16.

Detection of Pathogenic Leptospira Bacteria in Pinniped Populations via PCR and Identification of a Source of Transmission for Zoonotic Leptospirosis in the Marine Environment - (Peer Reviewed Journal)

Cameron, C.E., Zuerner, R.L., Raverty, S., Colegrove, K.M., Norman, S., Lambourn, D.M., Jeffries, S.J., Gulland, F.M. 2008. Detection of Pathogenic Leptospira Bacteria in Pinniped Populations via PCR and Identification of a Source of Transmission for Zoonotic Leptospirosis in the Marine Environment. Journal of Clinical Microbiology. 46(5):1728-1733.

Leptospira Protein Expression During Infection - (Abstract Only)

Zuerner, R.L. 2008. Leptospira Protein Expression During Infection [abstract]. Gordon Research Conference: Biology of Spirochetes. Poster No. 2-46.

Genome Sequence of the Saprophyte Leptospira Biflexa Provides Insights into the Evolution of Leptospira and the Pathogenesis of Leptospirosis     - (Peer Reviewed Journal)

Picardeau, M., Bulach, D.M., Bouchier, C., Zuerner, R.L., Zidane, N., Wilson, P.J., Creno, S., Kuczek, E.S., Bommezzadri, S., Davis, J.C., Mcgrath, A., Roche, D., Johnson, M.J., Boursaux-Eude, C., Seemann, T., Rouy, Z., Coppel, R.L., Rood, J.I., Lajus, A., Davies, J.K., Medigue, C., Adler, B. 2008. Genome Sequence of the Saprophyte Leptospira Biflexa Provides Insights into the Evolution of Leptospira and the Pathogenesis of Leptospirosis. PLoS One. 3(2):e1607. Available: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0001607.

Antigenic Targets of the Bovine Humoral Response to PDD-associated Spirochetes Change with Subsequent Exposure - (Abstract Only)

(14-Sep-07)

Whole-genome Sequencing of the Saprophyte L. biflexa and Comparative Genomics of Pathogoenic and Saprophytic Leptospira Species - (Abstract Only)

Picardeau, M., Bulach, D.M., Bouchier, C., Zuerner, R.L., Zidane, N., Wilson, P.J., Creno, S., Kuczek, E.S., Bommezzadri, S., Davis, J.C., Mcgrath, A., Roche, D., Johnson, M.J., Boursaux-Etude, C., Seemann, T., Rouy, Z., Coppel, R.L., Rood, J.I., Lajus, A., Davies, J.K., Medigue, C., Adler, B. 2007. Whole-genome Sequencing of the Saprophyte L. biflexa and Comparative Genomics of Pathogoenic and Saprophytic Leptospira Species [abstract]. International Leptospirosis Society. p. 114.

Lesion Formation and Antibody Response Induced by Papillomatous Digital Dermatitis-Associated Spirochetes in a Murine Abscess Model - (Peer Reviewed Journal)

Elliott, M.K., Alt, D.P., Zuerner, R.L. 2007. Lesion Formation and Antibody Response Induced by Papillomatous Digital Dermatitis (PDD)-associated spirochetes in a Murine Abscess Model. Infection and Immunity. 75(9):4400-4408.

Papillomatous Digital Dermatitis Spirochetes Suppress the Bovine Macrophage Innate Immune Response     - (Peer Reviewed Journal)

Zuerner, R.L., Heidari, M., Elliott, M.K., Alt, D.P., Neill, J.D. 2007. Papillomatous Digital Dermatitis Spirochetes Suppress the Bovine Macrophage Innate Immune Response. Veterinary Microbiology. 125(2007):256-264.

Role for Msh5 in the Regulation of Ig Class Switch Recombination     - (Peer Reviewed Journal)

Sekine, H., Ferreira, R., Pan-Hammarstrom, Q., Graham, R.R., Ziemba, B., De Vries, S.S., Liu, J., Hippen, K., Koeuth, T., Ortmann, W., Iwahori, A., Elliott, M.K., Offer, S., Skon, C., Du, L., Novitzke, J., Lee, A.T., Zhao, N., Tompkins, J.D., Altshuler, D., Gregersen, P.K., Cunningham-Rundles, C., Harris, R.S., Her, C., Nelson, D.L., Hammarstrom, L., Gilkeson, G.S., Behrens, T.W. 2007. Role for Msh5 in the Regulation of lg Class Switch Recombination. Proceedings of the National Academy of Sciences. 104(17):7193-7198.

Bovine Immune Response to Papillomatous Digital Dermatitis (PDD)-Associated Spirochetes are Skewed in Isolate Reactivity and Subclass Elicitation - (Abstract Only)

Elliott, M.K. 2006. Bovine Immune Response to Papillomatous Digital Dermatitis (PDD)-Associated Spirochetes are Skewed in Isolate Reactivity and Subclass Elicitation [abstract]. American Society for Microbiology 107th General Meeting. p. 233.

Role of MHC-Linked Genes in Autoantigen Selection and Renal Disease in a Murine Model of Systemic Lupus Erythematosus - (Peer Reviewed Journal)

Sekine, H., Graham, K.L., Zhao, S., Elliott, M., Ruiz, P., Utz, P.J., Gilkeson, G.S. 2006. Role of MHC-Linked Genes in Autoantigen Selection and Renal Disease in a Murine Model of Systemic Lupus Erythematosus. Journal of Immunology. 177(10):7423-34.