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Research Project:
GENOMIC AND FUNCTIONAL ANALYSIS OF THE MUCOSAL IMMUNE RESPONSE AND ITS ROLE IN PROTECTION AGAINST RESPIRATORY PATHOGENS IN POULTRY
Location: Exotic and Emerging Avian Viral Diseases Research Unit
Publications
(Clicking on the reprint icon
will take you to the publication reprint.)
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Protection from clinical disease against three highly virulent strains of Newcastle disease virus following in ovo application of an antibody-antigen complexed vaccine in maternally-antibody positive chickens
- (Peer Reviewed Journal)
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| Kapczynski, D.R., Martin, A., Haddad, E.E., King, D.J. 2012. Protection from clinical disease against three highly virulent strains of Newcastle disease virus following in ovo application of an antibody-antigen complexed vaccine in maternally-antibody positive chickens. Avian Diseases. 56(3):555-560. |
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Molecular signatures associated with Mx-1 mediated resistance to highlyl pathogenic influenza virus infections: mechanisms of survival
- (Peer Reviewed Journal)
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| Cilloniz, C., Pantin Jackwood, M.J., Ni, C., Carter, V.S., Korth, M.J., Swayne, D.E., Tumpey, T.M., Katze, M.G. 2012. Molecular signatures associated with Mx-1 mediated resistance to highlyl pathogenic influenza virus infections: mechanisms of survival. Journal of Virology. 86:2437-2446. |
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Chicken interferon alpha pretreatment reduces virus replication of pandemic H1N1 and H5N9 avian influenza viruses in different avian species lung cell cultures
- (Peer Reviewed Journal)
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| Jiang, H., Yang, H., Kapczynski, D.R. 2011. Chicken interferon alpha pretreatment reduces virus replication of pandemic H1N1 and H5N9 avian influenza viruses in different avian species lung cell cultures. Virology Journal.8:447. |
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Pandemic H1N1 influenza virus in Chilean commercial turkeys with genetic and serologic comparisons to U.S. H1N1 avian influenza vaccine isolates
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| Kapczynski, D.R., Gonder, E., Tilley, B., Hernandez, A., Hodgson, J., Wojcinski, H., Jiang, H., Suarez, D.L. 2011. Pandemic H1N1 influenza virus in Chilean commercial turkeys with genetic and serologic comparisons to U.S. H1N1 avian influenza vaccine isolates. Avian Diseases. 55(4):633-41. |
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Pathogenicity of reassortant H5N1 highly pathogenic avian influenza viruses in domestic ducks
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| Pantin Jackwood, M.J., Wasilenko, J.L., Cagle, C.A., Jadhao, S. 2011. Pathogenicity of reassortant H5N1 highly pathogenic avian influenza viruses in domestic ducks [abstract]. American Association of Avian Pathologists Annual Meeting, St. Louis, Missouri, July 16-19, 2011. CD-ROM. |
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Evaluation of cytokine gene expression after avian influenza virus infection in avian cell lines and primary cell cultures
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| Shepherd, E.M., Cagle, C.A., Pantin Jackwood, M.J., Faulkner, O.B., Wasilenko, J.L., Smith, D.M. 2011. Evaluation of cytokine gene expression after avian influenza virus infection in avian cell lines and primary cell cultures [abstract]. American Association of Avian Pathologists Annual Meeting, July 16-19, 2011, St. Louis, Missouri. CD-ROM. |
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Cross reactive cellular immune responses in chickens previously exposed to low pathogenic avian influenza
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| Kapczynski, D.R., Liljebjelke, K.A., Kulkarni, G., Hunt, H.D., Jiang, H., Petkov, D. 2011. Cross reactive cellular immune responses in chickens previously exposed to low pathogenic avian influenza. Biomed Central (BMC) Genomics. 5(4):S13. |
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Association of Mx1 Asn 631 variant alleles with enhanced resistance and altered cytokine response in chickens infected with a highly pathogenic avian influenza virus
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| Ewald, S.J., Kapczynski, D.R., Livant, E.J., Suarez, D.L., Ralph, J., Mcleod, S., Miller, C. 2011. Association of Mx1 Asn 631 variant alleles with enhanced resistance and altered cytokine response in chickens infected with a highly pathogenic avian influenza virus. Immunogenetics. 63(6):363-375. |
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The pathogenicity of H7 subtype avian influenza viruses in chickens, turkeys and ducks
- (Peer Reviewed Journal)
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| Spackman, E., Gelb, J., Preskenis, L., Ladman, B., Pope, C., Pantin Jackwood, M.J., Mckinley, E.T. 2010. The pathogenesis of low pathogenicity H7 avian influenza viruses in chickens, ducks and turkeys. Virology Journal. 7:331. |
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Intranasal application of alpha interferon reduces morbidity associated with low pathogenic avian influenza infection
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| (27-Aug-10) |
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Mucosal vaccination with a codon-optimized hemagglutinin gene expressed by attenuated Salmonella elicits a protective immune response in chickens against highly pathogenic avian influenza
- (Peer Reviewed Journal)
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| Liljebjelke, K.A., Petkov, D., Kapczynski, D.R. 2010. Mucosal vaccination with a codon-optimized hemagglutinin gene expressed by attenuated Salmonella elicits a protective immune response in chickens against highly pathogenic avian influenza. Vaccine. 28(27):4430-4437. |
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Cross reactive cytotoxic T lymphocytes from MHC-defined birds against homologous and heterologous avian influenza subtypes
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| Kapczynski, D.R., Liljebjelke, K.A., Kulkarni, G., Hunt, H.D., Jiang, H., Petkov, D. 2010. Cross reactive cytotoxic T lymphocytes from MHC-defined birds against homologous and heterologous avian influenza subtypes [abstract]. International Symposium on Animal Genomics for Animal Health, May 31-June 2, 2010, Paris, France. p. 18. |
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Serologic cross reactivity of avian influenza H1 vaccinated commercial U.S. turkeys to the emergent H1N1 influenza virus
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| (18-Feb-10) |
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Serologic cross reactivity of serum samples from avian influenza vaccinated commercial U.S. turkeys to the emergent H1N1 influenza virus
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| Kapczynski, D.R., Gonder, E., Tilley, B., Suarez, D.L., Swayne, D.E. 2010. Serologic cross reactivity of serum samples from avian influenza vaccinated commercial U.S. turkeys to the emergent H1N1 influenza virus [abstract]. Western Poultry Disease Conference. April 18-21, 2010, Vancouver, BC, Canada. CDROM. |
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Vaccination of SPF chickens with recombinant HVT expressing the HA from H5N1 highly pathogenic avian influenza protects against lethal challenge
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| Kapczynski, D.R., Esaki, M., Jackwood, M.W., Moore, K.M. 2010. Vaccination of SPF chickens with recombinant HVT expressing the HA from H5N1 highly pathogenic avian influenza protects against lethal challenge [abstract]. Western Poultry Disease Conference. April 18-21, 2010, Vancouver, BC, Canada. CDROM. |
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Innate resistance to avian influenza: Of MHC's and Mx proteins
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| Kapczynski, D.R., Ewald, S., Livant, E., Suarez, D.L., Swayne, D.E. 2009. Innate resistance to avian influenza: Of MHC's and Mx proteins [abstract]. NE-1034 Annual Technical Committee Meeting: Genetic Bases for Resistance and Immunity to Avian Diseases. October 4-5, 2009, Fayetteville, Arkansas. CDROM. |
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Salmonella expression of the avian influenza HA and M2e genes for protection of poultry from lethal challenge
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| (09-Sep-09) |
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Vaccination of chickens with recombinant salmonella expressing the M2e and CD154 increase protection and decrease viral shedding following low pathogenic avian influenza challenge
- (Peer Reviewed Journal)
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| Layton, S.L., Kapczynski, D.R., Cox, M.M., Higgins, S., Higgins, J., Wolfenden, A.D., Liljebjelke, K.A., Bottje, W.G., Swayne, D.E., Berghman, L.R., Kwon, Y.M., Hargis, B.M., Cole, K. 2009. Vaccination of chickens with recombinant salmonella expressing the M2e and CD154 increase protection and decrease viral shedding following low pathogenic avian influenza challenge. Poultry Science. 88(11):2244-2252. |
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Identification and characterization of two distinct bursal B-cell subpopulations following infectious bursal disease virus infection of White Leghorn chickens
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| Petkov, D.I., Linneman, E.G., Kapczynski, D.R., Sellers, H.S. 2009. Identification and characterization of two distinct bursal B-cell subpopulations following infectious bursal disease virus infection of White Leghorn chickens. Avian Diseases. 53(3):347-355. |
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Cross reactive immunity derived from chickens infected with H9N2 low pathogenic avian influenza against homologous and heterosubtypic challenge
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| Kapczynski, D.R., Petkov, D., Kulkarni, G., Hunt, H.D., Liljebjelke, K.A. 2009. Cross reactive immunity derived from chickens infected with H9N2 low pathogenic avian influenza against homologous and heterosubtypic challenge [abstract]. 5th Orthomyxovirus Research Conference, September 9-12, 2009, Freiburg, Germany. p. 32. |
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In vitro comparison of the cytokine response to avian influenza virus from peripheral blood lymphocyles isolated from chickens differing in Mx631 gene polymorphism
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| Kapczynski, D.R., Ewald, S., Livant, E., Kaltenboeck, L., Suarez, D.L. 2009. In vitro comparison of the cytokine response to avian influenza virus from peripheral blood lymphocyles isolated from chickens differing in Mx631 gene polymorphism [abstract]. Abstracts of the 146th American Veterinary Medical Association Annual Convention, July 12-15, 2009, Seattle, Washington. 2009 CDROM. |
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Differences in sialic acid repertoire provides a molecular platform for replication of both avian and mammalian influenza viruses in turkeys but not chickens
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| Kapczynski, D.R., Tilley, B., Gonder, E., Smith, C., Jackson, S., Liljebjelke, K.A., Petkov, D. 2009. Differences in sialic acid repertoire provides a molecular platform for replication of both avian and mammalian influenza viruses in turkeys but not chickens [abstract]. 7th International Avian Influenza Symposium, April 5-8, 2009, Athens, Georgia. p. 87. |
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Cross reactive antibody and cytotoxic T lymphocytes from avian influenza H9N2 infected chickens against homologous and heterologous avian influenza isolates
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| Kapczynski, D.R., Liljebjelke, K.A., Kulkarni, G., Hunt, H.D., Petkov, D. 2009. Cross reactive antibody and cytotoxic T lymphocytes from avian influenza H9N2 infected chickens against homologous and heterologous avian influenza isolates [abstract]. 7th International Avian Influenza Symposium, April 5-8, 2009, Athens, Georgia. p. 87. |
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Vaccine induced protection from egg production losses in commercial turkey breeder hens following experimental challenge with a triple reassortant H3N2 avian influenza virus
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| Kapczynski, D.R., Gonder, E., Liljebjelke, K.A., Lippert, R., Petkov, D., Tilley, B. 2009. Vaccine induced protection from egg production losses in commercial turkey breeder hens following experimental challenge with a triple reassortant H3N2 avian influenza virus. Avian Diseases. 53:7-15. |
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Influenza vaccines for avian species
- (Book / Chapter)
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| Kapczynski, D.R., Swayne, D.E. 2009. Influenza vaccines for avian species. In: Compans, R.W., Orenstein, W.A., editors. Vaccines for Pandemic Influenza, Current Topics in Microbiology and Immunology. Berlin: Springer-Verlag. p. 133-152. |
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The role of vaccines and biosecurity in control of H3N2 swine influenza infection in turkey breeder flocks
- (Proceedings)
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| Tilley, B., Kapczynski, D.R., Gonder, E., Smith, C., Jackson, S. 2008. The role of vaccines and biosecurity in control of H3N2 swine influenza infection in turkey breeder flocks. In: Proceedings of the American Association of Avian Pathologists Annual Meeting, July 19-23, 2008, New Orleans, Lousiana. CDROM. |
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The influence of immunogenomics on the innate immune response to avian influenza-comparison of toll-like receptor 7 and cytokine responses between chickens and ducks
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| Kapczynski, D.R., Smith, A.L., Philbin, V., Liljebjelke, K.A., Pantin Jackwood, M.J. 2008. The influence of immunogenomics on the innate immune response to avian influenza-comparison of toll-like receptor 7 and cytokine responses between chickens and ducks [abstract]. In: Proceedings of the American Association of Avian Pathologists annual meeting, July 19-23, 2008, New Orleans, Louisiana. p. 85. |
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Development and evaluation of a potential universal Salmonella-vectored avian influenza vaccine
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| Hargis, B.M., Layton, S.L., Kapczynski, D.R., Cole, K., Cox, M.M., Ywon, Y.M., Bergham, L.R., Liljebjelke, K.A., Bottje, W.J. 2008. Development and evaluation of a potential universal Salmonella-vectored avian influenza vaccine [abstract]. Poultry Science Association Centennial Meeting, July 20-23, 2008, Ontario, Canada. CDROM. |
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Transcriptional analysis of the innate immune response using the avian innate immunity microarray
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| Chung, I.T., Keeler, C.L., Kapczynski, D.R., Doughtery, L., Maughan, M.N. 2008. Transcriptional analysis of the innate immune response using the avian innate immunity microarray [abstract]. Immunobiology and Pathogenesis of Influenza Infection meeting, June 1-3, 2008, Atlanta, Georgia. CDROM. |
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Microarray analysis following infection with highly pathogenic avian influenza H5N1 virus in naive and vaccinated SPF chickens
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| Kapczynski, D.R., Afonso, C.L., Pantin Jackwood, M.J., Liljebjelke, K.A., Sarmento, L., Suarez, D.L., Swayne, D.E. 2008. Microarray analysis following infection with highly pathogenic avian influenza H5N1 virus in naive and vaccinated SPF chickens [abstract]. In: Proceedings of Avian Immunology Research Group Conference, June 24-27, 2008, Queensland, Australia. p. 22. |
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Polymorphism in chicken Mx gene influences susceptibility to avian influenza virus infection
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| Ewald, S.J., Livant, E.J., Kaltenboeck, L., Kapczynski, D.R., Suarez, D.L., Ralph, J., Mcleod, S., Miller, C. 2008. Polymorphism in chicken Mx gene influences susceptibility to avian influenza virus infection [abstract]. Avian Immunology Research Group. p. 1. |
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Comparison of inactivated H3 avian influenza vaccines to protect turkey hens against egg production losses following challenge with a recent H3N2 field isolate
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| Kapczynski, D.R., Liljebjelke, K.A., Gonder, E., Lippert, R., Tilley, B. 2008. Comparison of inactivated H3 avian influenza vaccines to protect turkey hens against egg production losses following challenge with a recent H3N2 field isolate [abstract]. In: Proceedings of the 23rd World Poultry Congress, June 29-July 4, 2008, Brisbane, Australia. CDROM. |
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